The interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to interleukin-7. (Q33943574)

30 July 2017

title

The interaction of LCK and the CD4 co-receptor alters the dose response of T-cells to interleukin-7. (English)

1 reference

30 July 2017

author name string

Christina Kittipatarin

series ordinal

1

1 reference

30 July 2017

Nuska Tschammer

series ordinal

2

1 reference

30 July 2017

Annette R Khaled

series ordinal

3

1 reference

30 July 2017

publication date

28 April 2010

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30 July 2017

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30 July 2017

volume

131

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30 July 2017

issue

2

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30 July 2017

page(s)

170-181

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Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy

30 July 2017

cites work

1 reference

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Ex vivo expansion of memory CD8 T cells from lymph nodes or spleen through in vitro culture with interleukin-7

28 July 2018

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Engagement of the CD4 receptor affects the redistribution of Lck to the immunological synapse in primary T cells: implications for T-cell activation during human immunodeficiency virus type 1 infection.

28 July 2018

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Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets

28 July 2018

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IL-7 promotes T cell proliferation through destabilization of p27Kip1.

28 July 2018

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Cbp deficiency alters Csk localization in lipid rafts but does not affect T-cell development

28 July 2018

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Cytokine-driven cell cycling is mediated through Cdc25A.

28 July 2018

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Characterization of an interleukin-7-dependent thymic cell line derived from a p53(-/-) mouse

28 July 2018

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IL-7 is critical for homeostatic proliferation and survival of naive T cells

28 July 2018

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A potential role for interleukin-7 in T-cell homeostasis

28 July 2018

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IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation

28 July 2018

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Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis

28 July 2018

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Differential requirement of the cytoplasmic subregions of gamma c chain in T cell development and function

28 July 2018

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Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

28 July 2018

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Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

28 July 2018

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Structures of Src-family tyrosine kinases

28 July 2018

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The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

28 July 2018

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Distinct roles for CD4 and CD8 as co-receptors in antigen receptor signalling

28 July 2018

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Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

28 July 2018

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Activation of src family kinases in human pre-B cells by IL-7.

28 July 2018

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The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

28 July 2018

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Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

28 July 2018

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Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

28 July 2018

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Profound block in thymocyte development in mice lacking p56lck

28 July 2018

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Hepatic interleukin-7 expression regulates T cell responses

28 July 2018

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Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells.

29 October 2018

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Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.

29 October 2018

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IL-7R alpha gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes.

29 October 2018

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A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation

29 October 2018

1 reference

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Stat5a/b are essential for normal lymphoid development and differentiation

29 October 2018

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Cross-regulation of JAK and Src kinases

29 October 2018

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A dose effect of IL-7 on thymocyte development

29 October 2018

1 reference

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Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation

29 October 2018

1 reference

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Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+CD25+ regulatory T cells versus CD8+ memory T cells.

29 October 2018

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A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells

29 October 2018

1 reference

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TCR signals mediated by Src family kinases are essential for the survival of naive T cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

Cytokine-independent Jak3 activation upon T cell receptor (TCR) stimulation through direct association of Jak3 and the TCR complex

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

Interleukin‐7 activates p56lck and p59fyn, two tyrosine kinases associated with the p90 interleukin‐7 receptor in primary human T cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892797

Lymphoproliferative disorders in an IL-7 transgenic mouse line

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20433867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of increasing IL-7 availability on lymphocytes during and after lymphopenia-induced proliferation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20433867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell cycling through Cdc25A: transducer of cytokine proliferative signals

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20433867

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.IMLET.2010.04.007

1 reference

30 July 2017

1 reference

30 July 2017

1 reference