Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine [correction of pyrazolidinone-piperidine] growth hormone secretagogue (Q33944120)

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English	Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine [correction of pyrazolidinone-piperidine] growth hormone secretagogue	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Preclinical pharmacology of CP-424,391, an orally active pyrazolinone-piperidine [correction of pyrazolidinone-piperidine] growth hormone secretagogue (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

L C Pan

1

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30 July 2017

P A Carpino

2

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30 July 2017

B A Lefker

3

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30 July 2017

J A Ragan

4

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30 July 2017

S M Toler

5

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30 July 2017

J C Pettersen

6

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30 July 2017

D O Nettleton

7

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30 July 2017

O Ng

8

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30 July 2017

C M Pirie

9

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30 July 2017

K Chidsey-Frink

10

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30 July 2017

B Lu

11

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30 July 2017

D F Nickerson

12

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30 July 2017

D A Tess

13

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30 July 2017

M A Mullins

14

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30 July 2017

D B MacLean

15

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30 July 2017

P A DaSilva-Jardine

16

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30 July 2017

D D Thompson

17

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30 July 2017

publication date

1 February 2001

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30 July 2017

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30 July 2017

14

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30 July 2017

1

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30 July 2017

121-132

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30 July 2017

Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged oral treatment with MK-677, a novel growth hormone secretagogue, improves sleep quality in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protectant activity of hexarelin or growth hormone against postischemic ventricular dysfunction in hearts from aged rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroendocrine responses to a novel growth hormone secretagogue, L-692,429, in healthy older subjects

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https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of the growth hormone secretagogue MK-677 increases markers of bone turnover in healthy and functionally impaired elderly adults. The MK-677 Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of growth hormone supplementation on left ventricular morphology and myocyte function with the development of congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute cardiovascular and hormonal effects of GH and hexarelin, a synthetic GH-releasing peptide, in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human growth hormone and human aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of growth hormone (GH) releasing peptide-mimetic MK-677 stimulates the GH/insulin-like growth factor-I axis in selected GH-deficient adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac ischemia and impairment of vascular endothelium function in hearts from growth hormone-deficient rats: protection by hexarelin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C-dependent growth hormone releasing peptides stimulate cyclic adenosine 3',5'-monophosphate production by human pituitary somatotropinomas expressing gsp oncogenes: evidence for crosstalk between transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low basal and persistent pulsatile growth hormone secretion are revealed in normal and hyposomatotropic men studied with a new ultrasensitive chemiluminescence assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular growth-hormone-releasing peptide-6 stimulates eating without affecting plasma growth hormone responses in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A receptor in pituitary and hypothalamus that functions in growth hormone release

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoreactive Somatostatin in Rat Hypophyseal Portal Blood: Effects of Anesthetics*

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beneficial effects of growth hormone treatment in GH-deficient adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-677, an orally active growth hormone secretagogue, reverses diet-induced catabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GHRP-6 induces a biphasic calcium response in rat pituitary somatotrophs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidomimetic regulation of growth hormone secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular administration of the growth hormone-releasing peptide KP-102 increases food intake in free-feeding rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone secretagogue increases muscle strength during remobilization after canine hindlimb immobilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a new G-protein-linked receptor for growth hormone secretagogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a pituitary growth hormone-releasing peptide (GHRP) receptor subtype by photoaffinity labeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synergistic effects of His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 on growth hormone (GH)-releasing factor-stimulated GH release and intracellular adenosine 3',5'-monophosphate accumulation in rat primary pituitary cell culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of pulsatile growth hormone secretion by continuous infusion of a growth hormone-releasing peptide mimetic, L-692,429, in older adults--a clinical research center study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of a new growth hormone-releasing peptide receptor in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone secretagogues: characterization, efficacy, and minimal bioactive conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult growth hormone deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nonpeptidyl growth hormone secretagogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. I. An increase in potassium conductance is responsible for both the hyperpolarization and the decrease in intracellular free calcium produced by somatostatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Twenty-four-hour growth hormone (GH)-releasing peptide (GHRP) infusion enhances pulsatile GH secretion and specifically attenuates the response to a subsequent GHRP bolus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone-independent cardioprotective effects of hexarelin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptidomimetic Regulation of Growth Hormone Secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11322494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1385/ENDO:14:1:121

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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