NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia. (Q33947406)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

myelodysplastic syndrome

1 reference

Ying-Wei Lin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Zhenhua Zhang

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

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publication date

8 March 2005

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9 January 2020

number of pages

9

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inferred from page(s)

published in

Blood

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9 January 2020

volume

106

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9 January 2020

issue

1

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9 January 2020

page(s)

287-295

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The role of NUP98 gene fusions in hematologic malignancy

9 January 2020

cites work

1 reference

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EVI1 induces myelodysplastic syndrome in mice

5 July 2018

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Transformation of myelodysplastic syndrome to acute lymphoblastic leukemia: a case report and review of the literature

5 July 2018

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Anemia, thrombocytopenia, leukocytosis, extramedullary hematopoiesis, and impaired progenitor function in Pten+/-SHIP-/- mice: a novel model of myelodysplasia

5 July 2018

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5 July 2018

Myelodysplastic syndrome

1 reference

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The myelodysplastic syndrome(s): a perspective and review highlighting current controversies

5 July 2018

1 reference

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Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13).

5 July 2018

1 reference

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GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta

5 July 2018

1 reference

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The World Health Organization (WHO) classification of the myeloid neoplasms

5 July 2018

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Myelodysplastic syndrome overview

5 July 2018

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Bethesda proposals for classification of lymphoid neoplasms in mice

5 July 2018

1 reference

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A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9

5 July 2018

1 reference

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NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

Stromal inhibition of megakaryocytic differentiation correlates with blockade of signaling by protein kinase C-epsilon and ERK/MAPK.

5 July 2018

1 reference

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NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

5 July 2018

1 reference

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Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

t(9;11)(p22;p15) in acute myeloid leukemia results in a fusion between NUP98 and the gene encoding transcriptional coactivators p52 and p75-lens epithelium-derived growth factor (LEDGF).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

Frequent co-expression of the HOXA9 and MEIS1 homeobox genes in human myeloid leukemias

5 July 2018

1 reference

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The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in an NUP98-TOP1 fusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

NUP98 is fused to PMX1 homeobox gene in human acute myelogenous leukemia with chromosome translocation t(1;11)(q23;p15).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways

5 July 2018

1 reference

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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

Hematopathologic findings in the myeloproliferative disorders.

5 July 2018

1 reference

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Acute leukemia after a primary myelodysplastic syndrome: immunophenotypic, genotypic, and clinical characteristics.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

NUP98 is fused to adducin 3 in a patient with T-cell acute lymphoblastic leukemia and myeloid markers, with a new translocation t(10;11)(q25;p15).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

The (4;11)(q21;p15) translocation fuses the NUP98 and RAP1GDS1 genes and is recurrent in T-cell acute lymphocytic leukemia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1201424

Regulation of c-Myc and Max in megakaryocytic and monocytic-macrophagic differentiation of K562 cells induced by protein kinase C modifiers: c-Myc is down-regulated but does not inhibit differentiation

29 October 2018

1 reference

12 December 2020

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

1 reference

12 December 2020

Novel NUP98-HOXC11 fusion gene resulted from a chromosomal break within exon 1 of HOXC11 in acute myeloid leukemia with t(11;12)(p15;q13)

1 reference

12 December 2020

Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1

1 reference

12 December 2020

The WHO classification of MDS does make a difference

1 reference

12 December 2020

Progression of a myelodysplastic syndrome to pre-B acute lymphoblastic leukaemia with unusual phenotype

1 reference

12 December 2020

Initial (prefibrotic) stages of idiopathic (primary) myelofibrosis (IMF) - a clinicopathological study

1 reference

12 December 2020

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

1 reference

12 December 2020

Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment

1 reference

12 December 2020

10.1182/BLOOD-2004-12-4794

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15755899%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

PubMed publication ID

15755899

1 reference