Drosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation (Q33948478)

30 July 2017

Drosophila histone deacetylase 6 protects dopaminergic neurons against {alpha}-synuclein toxicity by promoting inclusion formation (English)

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30 July 2017

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Guiping Du

1

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30 July 2017

Xiang Liu

2

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30 July 2017

Xinping Chen

3

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30 July 2017

Mei Song

4

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30 July 2017

Yan Yan

5

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30 July 2017

Renjie Jiao

6

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30 July 2017

Chih-Chen Wang

7

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30 July 2017

5 May 2010

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Molecular Biology of the Cell

30 July 2017

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30 July 2017

21

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13

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30 July 2017

2128-2137

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describes a project that uses

30 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2893978/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models

1 reference

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Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein

5 July 2018

1 reference

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Genetic neuropathology of Parkinson's disease.

5 July 2018

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Formation of toxic oligomeric alpha-synuclein species in living cells

5 July 2018

1 reference

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Parkinson's disease: clinical features and diagnosis

5 July 2018

1 reference

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Visual pattern memory requires foraging function in the central complex of Drosophila

5 July 2018

1 reference

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Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster

5 July 2018

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HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

5 July 2018

1 reference

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HDAC6, at the crossroads between cytoskeleton and cell signaling by acetylation and ubiquitination

5 July 2018

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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease

5 July 2018

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

5 July 2018

1 reference

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The role of G-protein-coupled receptor kinase 5 in pathogenesis of sporadic Parkinson's disease.

5 July 2018

1 reference

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HDAC6-p97/VCP controlled polyubiquitin chain turnover

5 July 2018

1 reference

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A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification

5 July 2018

1 reference

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The biochemistry of Parkinson's disease

5 July 2018

1 reference

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

5 July 2018

1 reference

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

5 July 2018

1 reference

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alpha-Synuclein locus triplication causes Parkinson's disease

5 July 2018

1 reference

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Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease

5 July 2018

1 reference

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

5 July 2018

1 reference

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Aggresomes protect cells by enhancing the degradation of toxic polyglutamine-containing protein

5 July 2018

1 reference

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Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease

5 July 2018

1 reference

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The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Toxic proteins in neurodegenerative disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

A Drosophila model of Parkinson's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Parkinson's disease. Second of two parts

5 July 2018

1 reference

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Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

5 July 2018

1 reference

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

5 July 2018

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

5 July 2018

1 reference

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

5 July 2018

1 reference

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Mapping of a gene for Parkinson's disease to chromosome 4q21-q23

5 July 2018

1 reference

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Structural properties of pore-forming oligomers of alpha-synuclein

5 July 2018

1 reference

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Superoxide dismutase overexpression protects dopaminergic neurons in a Drosophila model of Parkinson's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo.

29 October 2018

1 reference

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Rifampicin protects PC12 cells against MPP+-induced apoptosis and inhibits the expression of an alpha-Synuclein multimer.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

29 October 2018

1 reference

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Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Targeted gene expression in Drosophila dopaminergic cells using regulatory sequences from tyrosine hydroxylase

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Targeted expression of dominant negative proteasome mutants in Drosophila melanogaster

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Neurodegenerative disease: amyloid pores from pathogenic mutations.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Heat Shock Protein 70 Inhibits α-Synuclein Fibril Formation via Interactions with Diverse Intermediates

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893978

Gene targeting by homologous recombination in Drosophila

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20444973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E10-03-0200

1 reference

30 July 2017

1 reference

30 July 2017

1 reference