Advances in osmotic opening of the blood-brain barrier to enhance CNS chemotherapy (Q33956666)

30 July 2017

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title

Advances in osmotic opening of the blood-brain barrier to enhance CNS chemotherapy (English)

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30 July 2017

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1

Rapoport SI

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PubMed ID

11772287

30 July 2017

language of work or name

English

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publication date

1 October 2001

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Expert Opinion on Investigational Drugs

30 July 2017

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30 July 2017

10

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30 July 2017

10

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30 July 2017

1809-1818

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Use of recombinant vectors derived from herpes simplex virus 1 mutant tsK for short-term expression of transgenes encoding cytoplasmic and membrane anchored proteins in postmitotic polarized cortical neurons and glial cells in vitro

30 July 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Cellular and molecular neurosurgery: pathways from concept to reality--part II: vector systems and delivery methodologies for gene therapy of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Modulation of blood-brain barrier permeability

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Cell adhesion, cell junctions and the blood-brain barrier

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Tight-junctional modification as the basis of osmotic opening of the blood-brain barrier.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Osmotic opening of tight junctions in cerebral endothelium

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Hyperosmotic arabinose solutions open the tight junctions between brain capillary endothelial cells in tissue culture

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Osmotic opening of the blood-brain barrier in the monkey without associated neurological deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Reversible osmotic blood-brain barrier disruption in humans: implications for the chemotherapy of malignant brain tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Neurotoxicity of chemotherapeutic agents after blood-brain barrier modification: neuropathological studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Structural changes in the rat brain after carotid infusions of hyperosmolar solutions. An electron microscopic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

A mathematical model for vasogenic brain edema

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Distribution of intracranial contents after hypertonic urea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Mechanosensitive Ca2+ transients in endothelial cells from human umbilical vein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Pathway across blood-brain barrier opened by the bradykinin agonist, RMP-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Size-dependent blood-brain barrier opening demonstrated with [14C]sucrose and a 200,000-Da [3H]dextran

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Entry of neutralizing antibody to measles into brain and cerebrospinal fluid of immunized monkeys after osmotic opening of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Enhanced delivery improves the efficacy of a tumor-specific doxorubicin immunoconjugate in a human brain tumor xenograft model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Entry of [3H]norepinephrine, [125I]albumin and evans blue from blood into brain following unilateral osmotic opening of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Modification of the blood-brain barrier: increased concentration and fate of enzymes entering the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Pharmacokinetics of methotrexate in cerebrospinal fluid and serum after osmotic blood-brain barrier disruption in patients with brain lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Clearance of bilirubin from rat brain after reversible osmotic opening of the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Neurotoxicity of gadolinium contrast agents for magnetic resonance imaging in rats with osmotically disrupted blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Enhanced delivery of boronophenylalanine for neutron capture therapy by means of intracarotid injection and blood-brain barrier disruption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Enhanced delivery of [125I]glial cell line-derived neurotrophic factor to the rat CNS following osmotic blood-brain barrier modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Neurotoxicity of vincristine after the osmotic opening of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

The effects of the Na(+)/Ca(++) exchange blocker on osmotic blood-brain barrier disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Chemotherapy of brain tumors. Uptake of tritiated methotrexate by a transplantable intracerebral ependymoblastoma in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

The effect of hyperosmotic blood-brain barrier disruption on blood-to-tissue transport in ENU-induced gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Opening the blood-brain and blood-tumor barriers in experimental rat brain tumors: the effect of intracarotid hyperosmolar mannitol on capillary permeability and blood flow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Osmotic opening of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Model for drug uptake by brain tumors: effects of osmotic treatment and of diffusion in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Effect of hyperosmotic solutions on human brain tumour vasculature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Absence of contrast enhancement on CT brain scans of patients with supratentorial malignant gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

A randomized comparison of intra-arterial versus intravenous BCNU, with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Receptor-mediated transcytosis of transferrin across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Blood-brain barrier penetration and in vivo activity of an NGF conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

A new function for the LDL receptor: transcytosis of LDL across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Threshold Methotrexate Concentration for In Vivo Inhibition of DNA Synthesis in Normal and Tumorous Target Tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Chemotherapeutic implications of growth fraction and cell cycle time in glioblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Association of total dose intensity of chemotherapy in primary central nervous system lymphoma (human non-acquired immunodeficiency syndrome) and survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Applications of genetically manipulated mice in pharmacogenetics and pharmacogenomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

Reversible osmotic opening of the blood-brain barrier in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.10.10.1809

10.1517/13543784.10.10.1809

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

11772287