Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis. (Q33958556)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043939%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis (English)

1 reference

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10 March 2020

0 references

4

1 reference

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10 March 2020

Daniel Krappmann

8

1 reference

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10 March 2020

Rudi Beyaert

10

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10 March 2020

9

Marco Prinz

1 reference

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10 March 2020

author name string

Conor Mc Guire

1

1 reference

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10 March 2020

Lynn Elton

2

1 reference

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10 March 2020

Peter Wieghofer

3

1 reference

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10 March 2020

Sofie Voet

5

1 reference

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10 March 2020

Annelies Demeyer

6

1 reference

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10 March 2020

Daniel Nagel

7

1 reference

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10 March 2020

Geert van Loo

11

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10 March 2020

publication date

21 July 2014

1 reference

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Journal of Neuroinflammation

10 March 2020

published in

1 reference

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10 March 2020

volume

11

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10 March 2020

page(s)

124

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Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase

10 March 2020

cites work

1 reference

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Malt1-induced cleavage of regnase-1 in CD4(+) helper T cells regulates immune activation

5 July 2018

1 reference

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Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.

5 July 2018

1 reference

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MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo

5 July 2018

1 reference

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Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines.

5 July 2018

1 reference

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T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.

5 July 2018

1 reference

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Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation

5 July 2018

1 reference

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Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma.

5 July 2018

1 reference

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Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells

5 July 2018

1 reference

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A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

How regulatory T cells work

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

Multiple sclerosis: an immune or neurodegenerative disorder?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

The clinical investigation of pacatal in open psychiatric settings.

5 July 2018

1 reference

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The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

Interactions between promazine and antidepressants at the level of cellular distribution

5 July 2018

1 reference

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The history of the psychopharmacology of schizophrenia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

Single dose kinetics of thioridazine and its two psychoactive metabolites in healthy humans: a dose proportionality study.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4112826

Drug distribution between blood and brain as a determinant of antipsychotic drug effects

5 July 2018

1 reference

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Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1742-2094-11-124

Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2F1742-2094-11-124

Commentary by a clinical scientist in psychopharmacological research.

21 January 2018

1 reference

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https://api.crossref.org/works/10.1186%2F1742-2094-11-124

Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS.

21 January 2018

1 reference

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Antipsychotic drugs and dopamine-mediated responses in Aplysia neurons

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1742-2094-11-124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043939%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

1 reference

https://scigraph.springernature.com/pub.10.1186/1742-2094-11-124

9 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043939%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

25043939

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043939%20AND%20SRC:MED&resulttype=core&format=json