The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. (Q33958592)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10881170%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

review article

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title

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10881170%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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M L Dustin

1

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30 July 2017

J A Cooper

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 July 2000

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8 November 2019

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8 November 2019

volume

1

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8 November 2019

page(s)

23-29

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8 November 2019

issue

1

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Ligand-induced movement of lymphocyte membrane macromolecules. I. Analysis by immunofluorescence and ultrastructural radioautography

8 November 2019

cites work

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Transmembrane interactions and the mechanism of capping of surface receptors by their specific ligands

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Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. I. Relationship to cytoplasmic myosin

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A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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The immunological synapse: a molecular machine controlling T cell activation

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Three-dimensional segregation of supramolecular activation clusters in T cells

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Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

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Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response

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Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

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Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

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Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

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A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

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Membrane compartmentation is required for efficient T cell activation.

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation

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7 January 2021

Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

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LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes

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Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration

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Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors

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Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses

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Adhesion receptors of the immune system

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Making the T cell receptor go the distance: a topological view of T cell activation

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The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation

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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

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Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area.

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The structure and ligand interactions of CD2: implications for T-cell function

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Adhesive bond dynamics in contacts between T lymphocytes and glass-supported planar bilayers reconstituted with the immunoglobulin-related adhesion molecule CD58

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Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complex

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Effect of lengthening lymphocyte function-associated antigen 3 on adhesion to CD2

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The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus

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Leukocyte polarization in cell migration and immune interactions

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A central role for microvillous receptor presentation in leukocyte adhesion under flow

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Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes.

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Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1.

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7 January 2021

LFA-1-mediated adhesion is regulated by cytoskeletal restraint and by a Ca2+-dependent protease, calpain

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7 January 2021

Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin

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Biology of chemokine and classical chemoattractant receptors: differential requirements for adhesion-triggering versus chemotactic responses in lymphoid cells

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GlyCAM-1, a physiologic ligand for L-selectin, activates beta 2 integrins on naive peripheral lymphocytes

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Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

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Activation of mechanical responses in leukocytes

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Mapping the sensitivity of T cells with an optical trap: polarity and minimal number of receptors for Ca(2+) signaling

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Preferential attachment of membrane glycoproteins to the cytoskeleton at the leading edge of lamella

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7 January 2021

Ligand binding regulates the directed movement of beta1 integrins on fibroblasts

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7 January 2021

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

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7 January 2021

Crawling movements of lymphocytes on and beneath fibroblasts in culture

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7 January 2021

Cell migration: a physically integrated molecular process

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7 January 2021

Actin machinery: pushing the envelope.

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7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho.

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7 January 2021

Role of Rho in chemoattractant-activated leukocyte adhesion through integrins

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7 January 2021

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

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7 January 2021

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

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7 January 2021

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

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7 January 2021

Directed actin polymerization is the driving force for epithelial cell-cell adhesion

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7 January 2021

Polarity of T cell shape, motility, and sensitivity to antigen

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7 January 2021

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

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7 January 2021

The duration of antigenic stimulation determines the fate of naive and effector T cells.

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7 January 2021

Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

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7 January 2021

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

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7 January 2021

The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction

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7 January 2021

Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling

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7 January 2021

Regulation of the p70zap tyrosine protein kinase in T cells by the CD45 phosphotyrosine phosphatase

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7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

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7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

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7 January 2021

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

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7 January 2021

Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function

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7 January 2021

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

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7 January 2021

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

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7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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7 January 2021

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

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7 January 2021

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

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7 January 2021

WIP, a protein associated with wiskott-aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells

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7 January 2021

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

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7 January 2021

Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes

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7 January 2021

Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation

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7 January 2021

Reconstitution of actin-based motility of Listeria and Shigella using pure proteins

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7 January 2021

Control of actin assembly and disassembly at filament ends

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7 January 2021

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

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7 January 2021

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation.

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7 January 2021

The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization

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7 January 2021

Molecular mechanisms of nonmuscle myosin-II regulation

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7 January 2021

Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocation

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7 January 2021

Self-polarization and directional motility of cytoplasm

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7 January 2021

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

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7 January 2021

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

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7 January 2021

Congenital nephrotic syndrome in mice lacking CD2-associated protein

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7 January 2021

Lymphocyte responses and cytokines

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7 January 2021

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

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7 January 2021

CD8 Expression Allows T Cell Signaling by Monomeric Peptide-MHC Complexes

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7 January 2021

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

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7 January 2021

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

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7 January 2021

Dynamic interactions of macrophages with T cells during antigen presentation.

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7 January 2021

Detection of dimers of dimers of human leukocyte antigen (HLA)-DR on the surface of living cells by single-particle fluorescence imaging

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7 January 2021

Direct observation of single kinesin molecules moving along microtubules

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7 January 2021

Understanding the mechanisms of sustained signaling and T cell activation

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7 January 2021

T cell activation determined by T cell receptor number and tunable thresholds.

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7 January 2021

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

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7 January 2021

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.

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7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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7 January 2021

Selective modulation of protein kinase C-theta during T-cell activation

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7 January 2021

Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein

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7 January 2021

Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein

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7 January 2021

In vivo detection of dendritic cell antigen presentation to CD4(+) T cells.

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7 January 2021

Visualization of specific B and T lymphocyte interactions in the lymph node.

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7 January 2021

TCR-Mediated internalization of peptide-MHC complexes acquired by T cells

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7 January 2021

Identifiers

DOI

10.1038/76877

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10881170%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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