Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis (Q33958973)

30 July 2017

title

Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis (English)

1 reference

30 July 2017

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6

D L Longo

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30 July 2017

R K Srivastava

1

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30 July 2017

S J Sollott

2

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30 July 2017

L Khan

3

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30 July 2017

R Hansford

4

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30 July 2017

E G Lakatta

5

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30 July 2017

language of work or name

English

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publication date

1 August 1999

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Molecular and Cellular Biology

30 July 2017

published in

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30 July 2017

volume

19

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30 July 2017

issue

8

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30 July 2017

page(s)

5659-5674

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Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells

30 July 2017

cites work

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5 July 2018

Caspases: enemies within

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Regulation of Bcl-xl channel activity by calcium

5 July 2018

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Caspase activation is required for nitric oxide-mediated, CD95(APO-1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells.

5 July 2018

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Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

5 July 2018

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Production of nitric oxide by mitochondria

5 July 2018

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MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

5 July 2018

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Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway

5 July 2018

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Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

5 July 2018

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5 July 2018

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Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2

5 July 2018

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Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals.

5 July 2018

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The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis

5 July 2018

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Double identity for proteins of the Bcl-2 family

5 July 2018

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Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

5 July 2018

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

5 July 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

5 July 2018

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

5 July 2018

1 reference

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Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system.

5 July 2018

1 reference

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Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

5 July 2018

1 reference

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Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

5 July 2018

1 reference

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X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

5 July 2018

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

5 July 2018

1 reference

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Apoptosis suppression by bcl-2 is correlated with the regulation of nuclear and cytosolic Ca2+.

5 July 2018

1 reference

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Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to gamma-interferon and tumor necrosis factor-alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

5 July 2018

1 reference

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Pro-oxidants and mitochondrial Ca2+: their relationship to apoptosis and oncogenesis

5 July 2018

1 reference

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Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production

5 July 2018

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

5 July 2018

1 reference

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Bcl-2 and the regulation of programmed cell death

5 July 2018

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

5 July 2018

1 reference

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The stress-activated protein kinase subfamily of c-Jun kinases

5 July 2018

1 reference

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

5 July 2018

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Mitochondrial Ca2+ homeostasis in intact cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Bcl-2 overexpression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Apoptosis in the pathogenesis and treatment of disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Nitric oxide induces apoptosis in mouse thymocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Nitric oxide synthases: Roles, tolls, and controls

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Mitochondria: a historical review

5 July 2018

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Characterization of junD: a new member of the jun proto-oncogene family

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Phosphatidylinositol-derived precursors and signals

5 July 2018

1 reference

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The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

The oxidative inactivation of mitochondrial electron transport chain components and ATPase.

5 July 2018

1 reference

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Review of the current status of calcium and thiols in cellular injury

5 July 2018

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Calcium ions and oxidative cell injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Activation of stress-activated protein kinase/c-Jun NH2-terminal kinase and p38 kinase in calphostin C-induced apoptosis requires caspase-3-like proteases but is dispensable for cell death.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Injected cytochrome c induces apoptosis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Ordering the cell death pathway. Differential effects of BCL2, an interleukin-1-converting enzyme family protease inhibitor, and other survival agents on JNK activation in serum/nerve growth factor-deprived PC12 cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84418

Nitric oxide-mediated apoptosis in murine peritoneal macrophages

29 October 2018

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12 December 2020

Identification of a transitional preapoptotic population of thymocytes

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12 December 2020

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

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12 December 2020

Checkpoints of dueling dimers foil death wishes

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12 December 2020

Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation

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12 December 2020

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

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12 December 2020

Nitric oxide synthase activity in mitochondria

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12 December 2020

The overexpression of Bax produces cell death upon induction of the mitochondrial permeability transition

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12 December 2020

Nitric-oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome C release

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12 December 2020

Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis

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12 December 2020

Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry

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12 December 2020

Identifiers

DOI

10.1128/MCB.19.8.5659

1 reference

30 July 2017

1 reference

30 July 2017

1 reference