Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein (Q33959609)

30 July 2017

Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein (English)

1 reference

30 July 2017

R Fenrick

1

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30 July 2017

J M Amann

2

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30 July 2017

B Lutterbach

3

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30 July 2017

L Wang

4

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30 July 2017

J J Westendorf

5

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30 July 2017

J R Downing

6

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30 July 2017

S W Hiebert

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30 July 2017

language of work or name

English

0 references

publication date

1 October 1999

1 reference

Molecular and Cellular Biology

30 July 2017

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30 July 2017

19

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30 July 2017

6566-6574

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30 July 2017

10

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describes a project that uses

30 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC84626/fullTextXML

inferred from PubMed Central ID database lookup

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ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

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28 July 2018

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The ets family member Tel binds to the Fli-1 oncoprotein and inhibits its transcriptional activity

28 July 2018

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Ets transcription factors: nuclear effectors of the Ras-MAP-kinase signaling pathway

28 July 2018

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Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

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The partner gene of AML1 in t(16;21) myeloid malignancies is a novel member of the MTG8(ETO) family.

28 July 2018

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The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

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Groucho-dependent and -independent repression activities of Runt domain proteins

28 July 2018

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Analysis of ETV6 and ETV6-AML1 proteins in acute lymphoblastic leukaemia

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Deletions of CDKN1B and ETV6 in acute myeloid leukemia and myelodysplastic syndromes without cytogenetic evidence of 12p abnormalities

28 July 2018

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Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

28 July 2018

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Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters

28 July 2018

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Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression

28 July 2018

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

28 July 2018

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

28 July 2018

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

28 July 2018

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Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter

28 July 2018

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28 July 2018

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The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways

28 July 2018

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Molecular cloning of Elk-3, a new member of the Ets family expressed during mouse embryogenesis and analysis of its transcriptional repression activity

28 July 2018

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The TEL gene and human leukemia

28 July 2018

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Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

28 July 2018

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The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

28 July 2018

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The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1

28 July 2018

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The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript

28 July 2018

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How does the GAL4 transcription factor recognize the appropriate DNA binding sites in vivo?

28 July 2018

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WAF1, a potential mediator of p53 tumor suppression

28 July 2018

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Repression of AP-1-stimulated transcription by c-Ets-1.

28 July 2018

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

28 July 2018

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The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

28 July 2018

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Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

28 July 2018

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The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Repression of I-A beta gene expression by the transcription factor PU.1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Use of eukaryotic expression technology in the functional analysis of cloned genes

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

The c-ets-1 proto-oncogene has oncogenic activity and is positively autoregulated

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Molecular analysis of the ets genes and their products

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Analysis of TEL proteins in human leukemias

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Distinct requirements for chromatin assembly in transcriptional repression by thyroid hormone receptor and histone deacetylase.

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Non-killer cell-specific transcription factors silence the perforin promoter

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Deletion of the short arm of chromosome 12 is a secondary event in acute lymphoblastic leukemia with t(12;21)

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Molecular Cytogenetics of t(12;21)(p13;q22)

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84626

Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia

29 October 2018

1 reference

12 December 2020

ETV6-NTRK3 gene fusions and trisomy 11 establish a histogenetic link between mesoblastic nephroma and congenital fibrosarcoma

1 reference

12 December 2020

Frequent deletion of chromosome 12p12.3 in children with acute lymphoblastic leukaemia

1 reference

12 December 2020

Functional interference between retinoic acid or steroid hormone receptors and the oncoprotein Fli-1

1 reference

12 December 2020

Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

1 reference

12 December 2020

Gene splicing by overlap extension

1 reference

12 December 2020

Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood

1 reference

12 December 2020

TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor

1 reference

12 December 2020

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

1 reference

12 December 2020

TEL is one of the targets for deletion on 12p in many cases of childhood B-lineage acute lymphoblastic leukemia

1 reference

12 December 2020

TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.19.10.6566

1 reference

30 July 2017

1 reference

30 July 2017

1 reference