The immune-modulatory role of apolipoprotein E with emphasis on multiple sclerosis and experimental autoimmune encephalomyelitis (Q33960847)

30 July 2017

1 reference

20 November 2019

The immune-modulatory role of apolipoprotein E with emphasis on multiple sclerosis and experimental autoimmune encephalomyelitis (English)

1 reference

experimental autoimmune encephalomyelitis

30 July 2017

1 reference

20 November 2019

1 reference

20 November 2019

1 reference

19 September 2019

1 reference

20 November 2019

Hong-Liang Zhang

1

1 reference

30 July 2017

Jiang Wu

series ordinal

2

1 reference

30 July 2017

Jie Zhu

series ordinal

3

1 reference

30 July 2017

language of work or name

1 reference

31 May 2010

8 references

Clinical and Developmental Immunology

30 July 2017

25 April 2019

20 June 2019

30 June 2019

25 June 2019

19 September 2019

19 November 2019

20 November 2019

8 references

30 July 2017

25 April 2019

20 June 2019

30 June 2019

25 June 2019

19 September 2019

19 November 2019

20 November 2019

2010

1 reference

30 July 2017

186813

1 reference

Creative Commons Attribution 3.0 Unported

30 July 2017

7 references

25 April 2019

20 June 2019

30 June 2019

25 June 2019

19 September 2019

19 November 2019

on focus list of Wikimedia project

20 November 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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Infection induces a positive acute phase apolipoprotein E response from a negative acute phase gene: role of hepatic LDL receptors

5 July 2018

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Comparative proteomics analysis of cerebrospinal fluid of patients with Guillain-Barré syndrome

5 July 2018

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Impact of apoE genotype on oxidative stress, inflammation and disease risk

5 July 2018

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APOE genotype-specific differences in the innate immune response

5 July 2018

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5 July 2018

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5 July 2018

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The APOE4 genotype alters the response of microglia and macrophages to 17beta-estradiol

5 July 2018

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Proteomic identification of potential protein markers in cerebrospinal fluid of GBS patients

5 July 2018

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The association between apolipoprotein E and multiple sclerosis

5 July 2018

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APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers

5 July 2018

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Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice

5 July 2018

1 reference

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Experimental allergic encephalomyelitis: a misleading model of multiple sclerosis

5 July 2018

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Apolipoprotein-mediated pathways of lipid antigen presentation

5 July 2018

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The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

5 July 2018

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Biological markers in CSF and blood for axonal degeneration in multiple sclerosis

5 July 2018

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Apolipoprotein E4 as a target for developing new therapeutics for Alzheimer's disease

5 July 2018

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Development of biomarkers in multiple sclerosis

5 July 2018

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CD1d-dependent activation of NKT cells aggravates atherosclerosis.

5 July 2018

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Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

5 July 2018

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The common polymorphism of apolipoprotein E: geographical aspects and new pathophysiological relations

5 July 2018

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Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide

5 July 2018

1 reference

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Apolipoprotein E: possible therapeutic target for atherosclerosis

5 July 2018

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Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites

5 July 2018

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Alternative activation of macrophages

5 July 2018

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Apolipoprotein-E allele-specific regulation of nitric oxide production.

5 July 2018

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Association of polymorphisms in the apolipoprotein E region with susceptibility to and progression of multiple sclerosis

5 July 2018

1 reference

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Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.

5 July 2018

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Apolipoprotein E: far more than a lipid transport protein

5 July 2018

1 reference

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Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E

5 July 2018

1 reference

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Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

APOE genotype is a major predictor of long-term progression of disability in MS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E genotype related differences in brain lesions of multiple sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Association of the APOE epsilon4 allele with disease activity in multiple sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E and multiple sclerosis: a biochemical and genetic investigation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Human apolipoprotein E: the Alzheimer's disease connection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E: structure-function relationships

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E restricts interleukin-dependent T lymphocyte proliferation at the G1A/G1B boundary.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E polymorphism and coronary artery disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Phosphatidylinositol turnover in mitogen-activated lymphocytes. Suppression by low-density lipoproteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Direct suppression of lymphocyte induction by the immunoregulatory human serum low density lipoprotein, LDL-In

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

A lymphocyte-inhibiting factor isolated from normal human liver.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Abnormal in vivo metabolism of apolipoprotein E4 in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Cerebrospinal fluid and plasma apolipoproteins in patients with multiple sclerosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E distribution among human plasma lipoproteins: role of the cysteine-arginine interchange at residue 112.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns, and prediction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein (apo) E inhibits the capacity of monosodium urate crystals to stimulate neutrophils. Characterization of intraarticular apo E and demonstration of apo E binding to urate crystals in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E polymorphism in a Danish population compared to findings in 45 other study populations around the world

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

A pathway-dependent on apoE, ApoAI, and ABCA1 determines formation of buoyant high-density lipoprotein by macrophage foam cells.

5 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: variation by use of antihypertensive medication?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E allele 4 is not a sufficient or a necessary predictor of the development of Mild Cognitive Impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E4 enhances brain inflammation by modulation of the NF-kappaB signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E suppresses the type I inflammatory response in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E protects against bacterial lipopolysaccharide-induced lethality. A new therapeutic approach to treat gram-negative sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E modulates immune activation by acting on the antigen-presenting cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Microglial function in human APOE3 and APOE4 transgenic mice: altered arginine transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein-mediated lipid antigen presentation in B cells provides a pathway for innate help by NKT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E epsilon 4 is associated with rapid progression of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Influence of apolipoprotein E epsilon4 genotype on brain tissue integrity in relapsing-remitting multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

APOE genotypes in African American female multiple sclerosis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Lower levels of N-acetylaspartate in multiple sclerosis patients with the apolipoprotein E epsilon4 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Genotypes at the APOE and SCA2 loci do not predict the course of multiple sclerosis in patients of Portuguese origin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Association of APOE polymorphisms with disease severity in MS is limited to women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein genotype does not influence MS severity, cognition, or brain atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

No major association of ApoE genotype with disease characteristics and MRI findings in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Disease severity in Danish multiple sclerosis patients evaluated by MRI and three genetic markers (HLA-DRB1*1501, CCR5 deletion mutation, apolipoprotein E).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Accelerated evolution of brain atrophy and "black holes" in MS patients with APOE-epsilon 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E genotype does not influence the progression of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Lack of apolipoprotein-E exacerbates experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Novel role for apolipoprotein E in the central nervous system. Modulation of sulfatide content

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

APOE 4 polymorphism results in early cognitive deficits in an EAE model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

The insertion polymorphism in angiotensin-converting enzyme gene associated with the APOE epsilon 4 allele increases the risk of late-onset Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

[Analysis of the association of allelic variants of apolypoprotein E and interleukin 1 beta genes with multiple sclerosis in ethnic Tatars]

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Apolipoprotein E and mimetic peptide initiate a calcium-dependent signaling response in macrophages

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896842

Localization and replication of the systemic lupus erythematosus linkage signal at 4p16: interaction with 2p11, 12q24 and 19q13 in European Americans

29 October 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Apo E in multiple sclerosis and optic neuritis: the Apo E-o4 allele is associated with progression of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

No effect of APOE and PVRL2 on the clinical outcome of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Association of apolipoprotein E polymorphism to clinical heterogeneity of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F186813

Alterations in plasma lipoproteins and apolipoproteins in experimental allergic encephalomyelitis

21 January 2018

1 reference

12 December 2020

APOE genotypes in Greek multiple sclerosis patients: no effect on the MS Severity Score

1 reference

12 December 2020

Apolipoprotein E intrathecal synthesis is decreased in multiple sclerosis patients

1 reference

12 December 2020

Apoprotein E suppresses phytohemagglutinin-activated phospholipid turnover in peripheral blood mononuclear cells

1 reference

12 December 2020

Immunoregulatory plasma lipoproteins. Role of apoprotein E and apoprotein B

1 reference

12 December 2020

Brain MRI lesions and atrophy are related to depression in multiple sclerosis

1 reference

12 December 2020

The relationship of APOE genetic polymorphism with susceptibility to multiple sclerosis and its clinical phenotypes in Kuwaiti Arab subjects

1 reference

12 December 2020

Lesion pattern in patients with multiple sclerosis and depression

1 reference

12 December 2020

Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein, LDL-In

1 reference

12 December 2020

No association of apolipoprotein E epsilon4 genotype with faster progression or less recovery of relapses in a Spanish cohort of multiple sclerosis

1 reference

12 December 2020

HLA-DR,DQ and APOE genotypes and gender influence in Sardinian primary progressive MS

1 reference

12 December 2020

Genetic control of human apolipoprotein E polymorphism: comparison of one- and two-dimensional techniques of isoprotein analysis

1 reference

12 December 2020

Polymorphisms of apolipoprotein E and Japanese patients with multiple sclerosis

1 reference

12 December 2020

MS and cognition and APOE: the ongoing conundrum about biomarkers

1 reference

12 December 2020

Altered immune responses in apolipoprotein E-deficient mice

1 reference

12 December 2020

APOE epsilon4 is associated with impaired verbal learning in patients with MS

1 reference

12 December 2020

Apolipoprotein E-deficient mice have impaired innate immune responses to Listeria monocytogenes in vivo

1 reference

12 December 2020

APOE genotypes and disease severity in multiple sclerosis

1 reference

12 December 2020

Apoliprotein E and multiple sclerosis: impact of the epsilon-4 allele on susceptibility, clinical type and progression rate

1 reference

12 December 2020

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group

1 reference

12 December 2020

APOE epsilon2-4 and -491 polymorphisms are not associated with MS

1 reference

12 December 2020

Apolipoprotein E knock-out mice are highly susceptible to endotoxemia and Klebsiella pneumoniae infection

1 reference

12 December 2020

Cognitive dysfunction in multiple sclerosis.: II. Impact on employment and social functioning

1 reference

12 December 2020

Serum lipoproteins: Trojan horses of the immune response?

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/186813

1 reference

30 July 2017

1 reference

30 July 2017

1 reference