TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer (Q33965228)

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English	TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

author name string

Ji Yeon Baek

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Shelli M Morris

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Jean Campbell

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Nelson Fausto

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Matthew M Yeh

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

William M Grady

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

0 references

publication date

1 September 2010

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

International Journal of Cancer

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

127

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1060-1071

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

From molecular biology to targeted therapies for hepatocellular carcinoma: the future is now.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation.

1 reference

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5 July 2018

The genetic and environmental basis of hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.

1 reference

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5 July 2018

Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Raf kinase inhibitor protein is downregulated in hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Dysregulation of growth factor signaling in human hepatocellular carcinoma.

1 reference

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5 July 2018

Transcription factor YY1: structure, function, and therapeutic implications in cancer biology.

1 reference

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5 July 2018

Molecular pathways in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations

1 reference

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5 July 2018

Stable overexpression of Smad7 in human melanoma cells inhibits their tumorigenicity in vitro and in vivo

1 reference

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5 July 2018

Liver transplantation for malignancy

1 reference

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5 July 2018

Molecular mechanisms of hepatocarcinogenesis in transgenic mouse models of liver cancer

1 reference

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5 July 2018

Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

The biology of a prostate cancer metastasis suppressor protein: Raf kinase inhibitor protein

1 reference

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5 July 2018

Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

The role of Raf kinase inhibitor protein (RKIP) in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Nuclear factor YY1 inhibits transforming growth factor beta- and bone morphogenetic protein-induced cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation

1 reference

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5 July 2018

Blocking oncogenic Ras signaling for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Enhanced expression of cyclin E and cyclin A in human hepatocellular carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Role of transforming growth factor beta in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

The Hallmarks of Cancer

1 reference

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5 July 2018

Smad4/DPC4 silencing and hyperactive Ras jointly disrupt transforming growth factor-beta antiproliferative responses in colon cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Acceleration of c-myc-induced hepatocarcinogenesis by Co-expression of transforming growth factor (TGF)-alpha in transgenic mice is associated with TGF-beta1 signaling disruption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

Introduction of a murine p53 mutation corresponding to human codon 249 into a murine hepatocyte cell line results in growth advantage, but not in transformation

1 reference

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ras oncogenes in human cancer: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

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Molecular and genetic analysis of liver oncogenesis in transforming growth factor alpha transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

5 July 2018

The expression of transforming growth factor-alpha in cirrhosis, dysplastic nodules, and hepatocellular carcinoma: an immunohistochemical study of 70 cases.

1 reference

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Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

1 reference

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Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

29 October 2018

Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

29 October 2018

Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

29 October 2018

Expression of HER2 and its association with AP-2 in breast cancer

1 reference

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29 October 2018

Expression of Smad7 in hepatocellular carcinoma and dysplastic nodules: resistance mechanism to transforming growth factor-beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

29 October 2018

Conditional inactivation of the TGF-beta type II receptor using Cre:Lox

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2897914

29 October 2018

TGF-beta and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20020490

12 December 2020

based on heuristic

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DNA excision in liver by an albumin-Cre transgene occurs progressively with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/20020490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transforming growth factor alpha/epidermal growth factor receptor, hepatocyte growth factor/c-met and acidic fibroblast growth factor/fibroblast growth factor receptors during hepatocarcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20020490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of transforming growth factor (TGF)-alpha/epidermal growth factor receptor, hepatocyte growth Factor/c-met,TGF-beta receptor type II, and p53 expression in human hepatocellular carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20020490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-alpha and epidermal growth factor receptor in chronic liver disease and hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20020490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification and overexpression of cyclin D1 in human hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20020490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta and cell cycle regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20020490

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/IJC.25127

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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