Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity (Q33965673)

30 July 2017

Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity. (English)

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30 July 2017

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Yun Sok Lee

1

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Jung-whan Kim

Jung-whan Kim

2

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Simon Schenk

Simon Schenk

6

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Anne N. Murphy

Anne Murphy

9

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Randall S. Johnson

Randall S Johnson

12

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Jerrold M. Olefsky

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Jerrold M Olefsky

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30 July 2017

Olivia Osborne

3

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Da Young Oh

4

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Roman Sasik

5

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Ai Chen

7

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Heekyung Chung

8

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Steven M Watkins

10

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Oswald Quehenberger

11

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30 July 2017

language of work or name

English

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publication date

1 June 2014

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157

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1339-1352

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6

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describes a project that uses

30 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4114226/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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Selective inhibition of hypoxia-inducible factor 1α ameliorates adipose tissue dysfunction.

5 July 2018

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Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system.

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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

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Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity

5 July 2018

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5 July 2018

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Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance

5 July 2018

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Disruption of hypoxia-inducible factor 1 in adipocytes improves insulin sensitivity and decreases adiposity in high-fat diet-fed mice

5 July 2018

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Deficiency of the leukotriene B4 receptor, BLT-1, protects against systemic insulin resistance in diet-induced obesity

5 July 2018

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Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

5 July 2018

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Cellular hypoxia of pancreatic beta-cells due to high levels of oxygen consumption for insulin secretion in vitro

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Adipose tissue-specific inhibition of hypoxia-inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice

5 July 2018

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5 July 2018

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Hypoxia-mediated expression of 5-lipoxygenase-activating protein involves HIF-1alpha and NF-kappaB and microRNAs 135a and 199a-5p

5 July 2018

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Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Alterations in adipocyte free fatty acid re-esterification associated with obesity and weight reduction in man.

5 July 2018

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Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

5 July 2018

1 reference

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Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4114226

Carboxyatractylate inhibits the uncoupling effect of free fatty acids

29 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24906151

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2014.05.012

1 reference

30 July 2017

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30 July 2017

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