The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection (Q33971309)

30 July 2017

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title

The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection (English)

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30 July 2017

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A M Saunders

1

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30 July 2017

M K Trowers

2

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30 July 2017

R A Shimkets

3

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30 July 2017

S Blakemore

4

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30 July 2017

D J Crowther

5

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30 July 2017

T A Mansfield

6

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30 July 2017

D M Wallace

7

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30 July 2017

W J Strittmatter

8

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30 July 2017

A D Roses

9

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30 July 2017

language of work or name

English

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publication date

1 July 2000

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Biochimica et Biophysica Acta

30 July 2017

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30 July 2017

1502

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30 July 2017

1

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30 July 2017

85-94

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Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

1 reference

7 January 2021

ApoE genotype and survival from intracerebral haemorrhage

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E epsilon4 associated with chronic traumatic brain injury in boxing.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

The apolipoprotein E epsilon4 allele and outcome in cerebrovascular disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Predictors of cognitive decline after cardiac operation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Head injury, amyloid β and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

ApoE as a prognostic factor for post–traumatic coma

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E: structure-function relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E synthesis in human kidney, adrenal gland, and liver

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Cerebrospinal fluid proteins studied by two-dimensional gel electrophoresis and immunoblotting technique.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Expression of apolipoprotein E during nerve degeneration and regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E in nerve injury and repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E restricts interleukin-dependent T lymphocyte proliferation at the G1A/G1B boundary.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Avid binding of beta A amyloid peptide to its own precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Linkage of late-onset Alzheimer's disease with apolipoprotein E type 4 on chromosome 19.

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https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E genotype and Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E polymorphism and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

A high frequency of apolipoprotein E4 isoprotein in Japanese patients with late-onset nonfamilial Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

ApoE genotype is a risk factor in nonpresenilin early-onset Alzheimer's disease families

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Predictive value of apolipoprotein E genotyping in Alzheimer's disease: results of an autopsy series and an analysis of several combined studies

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

ApoE-epsilon 4 and early-onset Alzheimer's

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Lack of an association between apolipoprotein E epsilon 4 and Alzheimer's disease in elderly Nigerians

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Confirmation of the epsilon 4 allele of the apolipoprotein E gene as a risk factor for late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E in Alzheimer's disease risk and case detection: a case-control study

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Association of apolipoprotein E phenotypes with late onset Alzheimer's disease: population based study

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E4: Phenotype in patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Association of apolipoprotein E4 with sporadic Alzheimer's disease is more pronounced in early onset type.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E polymorphism in Japanese patients with Alzheimer's disease or vascular dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Abnormal degradative pathway of mitochondrial ATP synthase subunit c in late infantile neuronal ceroid-lipofuscinosis (Batten disease).

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Human apolipoprotein E allele-specific brain expressing transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Human APOE protein localized in brains of transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Visualization of differential gene expression using a novel method of RNA fingerprinting based on AFLP: analysis of gene expression during potato tuber development.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Exploring the metabolic and genetic control of gene expression on a genomic scale

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Identifying differences in mRNA expression by representational difference analysis of cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Identification of differentially expressed genes by restriction endonuclease-based gene expression fingerprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Description of the entire mRNA population by a 3' end cDNA fragment generated by class IIS restriction enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Expression monitoring by hybridization to high-density oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Serial analysis of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Discovering distinct genes represented in 29,570 clones from infant brain cDNA libraries by applying sequencing by hybridization methodology

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Gene-representing cDNA clusters defined by hybridization of 57,419 clones from infant brain libraries with short oligonucleotide probes

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

DNA sequence recognition by hybridization to short oligomers: experimental verification of the method on the E. coli genome

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Clone clustering by hybridization.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

Positive selection of candidate tumor-suppressor genes by subtractive hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4439%2800%2900035-1

7 January 2021

10.1016/S0925-4439(00)00035-1

Identifiers

DOI

1 reference

30 July 2017

1 reference