Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase (Q33974599)

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English	Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase (English)

1 reference

Europe PubMed Central

30 July 2017

3

object named as

Michael Karin

1 reference

Europe PubMed Central

30 July 2017

Aaron Ciechanover

4

object named as

Aaron Ciechanover

1 reference

Europe PubMed Central

30 July 2017

author name string

Ruthie E Amir

1

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30 July 2017

Hans Haecker

2

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Europe PubMed Central

30 July 2017

language of work or name

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publication date

1 April 2004

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Europe PubMed Central

30 July 2017

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Europe PubMed Central

30 July 2017

23

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Europe PubMed Central

30 July 2017

14

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Europe PubMed Central

30 July 2017

2540-2547

1 reference

Europe PubMed Central

30 July 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207366

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The NEDD8 pathway is essential for SCF(beta -TrCP)-mediated ubiquitination and processing of the NF-kappa B precursor p105.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

NF-kappaB in cancer: a marked target

1 reference

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21 January 2018

Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

1 reference

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21 January 2018

The involvement of the candidate proto-oncogene NFKB2/lyt-10 in lymphoid malignancies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207366

21 January 2018

Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

1 reference

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21 January 2018

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

1 reference

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21 January 2018

The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34

1 reference

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21 January 2018

Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway.

1 reference

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7 January 2021

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B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-kappa B p50

1 reference

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The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

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Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

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Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase

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11 October 2022

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Evolution and function of ubiquitin-like protein-conjugation systems

1 reference

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NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

1 reference

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NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

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SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

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Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

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Regulatory functions of ubiquitination in the immune system

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Series introduction: the transcription factor NF-kappaB and human disease

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A new NEDD8-ligating system for cullin-4A

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NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

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Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

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10.1038/SJ.ONC.1207366

1 reference

Europe PubMed Central

30 July 2017

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1 reference

Europe PubMed Central

30 July 2017

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