The selective norepinephrine reuptake inhibitor antidepressant reboxetine: pharmacological and clinical profile. (Q33976127)

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24 November 2019

review article

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title

The selective norepinephrine reuptake inhibitor antidepressant reboxetine: pharmacological and clinical profile (English)

1 reference

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24 November 2019

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Mihály Hajós

1

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24 November 2019

Joseph C Fleishaker

2

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24 November 2019

Jacqueline K Filipiak-Reisner

3

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24 November 2019

Mark T Brown

4

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24 November 2019

Erik H F Wong

5

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24 November 2019

publication date

1 January 2004

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CNS Neuroscience & Therapeutics

24 November 2019

published in

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24 November 2019

volume

10

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24 November 2019

issue

1

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24 November 2019

page(s)

23-44

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A molecular and cellular theory of depression

24 November 2019

cites work

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Stress, synaptic plasticity, and psychopathology

21 January 2018

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Interaction between a selective 5-HT1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT

21 January 2018

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Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression

21 January 2018

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Simultaneous analyses of the neurochemical and behavioral effects of the norepinephrine reuptake inhibitor reboxetine in a rat model of antidepressant action

21 January 2018

1 reference

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Reboxetine, a selective norepinephrine reuptake inhibitor, is an effective and well-tolerated treatment for panic disorder

21 January 2018

2 references

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2004.TB00002.X

21 January 2018

12 December 2020

Inhibition of median and dorsal raphe neurones following administration of the selective serotonin reuptake inhibitor paroxetine

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Absolute bioavailability of reboxetine enantiomers and effect of gender on pharmacokinetics

21 January 2018

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12 December 2020

Reboxetine: a double-blind comparison with fluoxetine in major depressive disorder

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12 December 2020

Serotonergic mediation of DRL 72s behavior: receptor subtype involvement in a behavioral screen for antidepressant drugs

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12 December 2020

Reboxetine, a unique selective NRI, prevents relapse and recurrence in long-term treatment of major depressive disorder.

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12 December 2020

Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action

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12 December 2020

Activity of serotonergic neurons in behaving animals

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12 December 2020

Dose proportionality of reboxetine enantiomers in healthy male volunteers

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12 December 2020

Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat.

1 reference

12 December 2020

Hemodynamic effects of reboxetine in healthy male volunteers

1 reference

12 December 2020

No effect of the new antidepressant reboxetine on CYP2D6 activity in healthy volunteers

1 reference

12 December 2020

Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes

1 reference

12 December 2020

Ketoconazole inhibits the clearance of the enantiomers of the antidepressant reboxetine in humans

1 reference

12 December 2020

Molecular control of locus coeruleus neurotransmission

1 reference

12 December 2020

The role of norepinephrine in the pathophysiology of cognitive disorders: potential applications to the treatment of cognitive dysfunction in schizophrenia and Alzheimer's disease

1 reference

12 December 2020

Role of locus coeruleus in attention and behavioral flexibility

1 reference

12 December 2020

Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level

1 reference

12 December 2020

Studies on the acute and chronic effects of reboxetine on extracellular noradrenaline and other monoamines in the rat brain

1 reference

12 December 2020

Second messenger-regulated protein kinases in the brain: their functional role and the action of antidepressant drugs

1 reference

12 December 2020

Correlation of high-frequency oscillations with the sleep-wake cycle and cognitive activity in humans

1 reference

12 December 2020

Reboxetine versus imipramine in the treatment of elderly patients with depressive disorders: a double-blind randomised trial

1 reference

12 December 2020

Double-blind, placebo-controlled study with reboxetine in inpatients with severe major depressive disorder

1 reference

12 December 2020

Role of norepinephrine in depression

1 reference

12 December 2020

Pharmacokinetics of single-dose reboxetine in volunteers with renal insufficiency

1 reference

12 December 2020

Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor

1 reference

12 December 2020

Pharmacological profile of reboxetine, a representative of new class of antidepressant drugs, selective noradrenaline reuptake inhibitor (NARI), given acutely

1 reference

12 December 2020

Pharmacokinetics of reboxetine in elderly patients with depressive disorders

1 reference

12 December 2020

Reboxetine: tolerability and safety profile in patients with major depression.

1 reference

12 December 2020

Norepinephrine involvement in antidepressant action

1 reference

12 December 2020

Effect of a selective 5-hydroxytryptamine reuptake inhibitor on brain extracellular noradrenaline: microdialysis studies using paroxetine

1 reference

12 December 2020

Reboxetine in the treatment of bulimia nervosa: a report of seven cases

1 reference

12 December 2020

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

1 reference

12 December 2020

Effects of reboxetine and sertraline treatments alone and in combination on the binding properties of cortical NMDA and beta1-adrenergic receptors in an animal model of depression

1 reference

12 December 2020

Chronic treatment with reboxetine by osmotic pumps facilitates its effect on extracellular noradrenaline and may desensitize alpha(2)-adrenoceptors in the prefrontal cortex

1 reference

12 December 2020

Effects of chronic antidepressant drug administration and electroconvulsive shock on locus coeruleus electrophysiologic activity.

1 reference

12 December 2020

Chronic treatment with desipramine facilitates its effect on extracellular noradrenaline in the rat hippocampus: studies on the role of presynaptic alpha2-adrenoceptors

1 reference

12 December 2020

Role of serotonin and noradrenaline in social dysfunction: a review of data on reboxetine and the Social Adaptation Self-evaluation Scale (SASS).

1 reference

12 December 2020

Reboxetine in seasonal affective disorder: an open trial

1 reference

12 December 2020

Reboxetine: the first selective noradrenaline re-uptake inhibitor

1 reference

12 December 2020

Reboxetine modulates the firing pattern of dopamine cells in the ventral tegmental area and selectively increases dopamine availability in the prefrontal cortex.

1 reference

12 December 2020

Gating of human theta oscillations by a working memory task.

1 reference

12 December 2020

Stimulant and anticataplectic effects of reboxetine in patients with narcolepsy: a pilot study.

1 reference

12 December 2020

Progressive attenuation of the firing activity of locus coeruleus noradrenergic neurons by sustained administration of selective serotonin reuptake inhibitors

1 reference

12 December 2020

Pharmacokinetics of reboxetine in healthy volunteers with different ethnic descents

1 reference

12 December 2020

Effect of the selective noradrenergic reuptake inhibitor reboxetine on the firing activity of noradrenaline and serotonin neurons

1 reference

12 December 2020

S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological, and neurochemical profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine

1 reference

12 December 2020

S33005, a novel ligand at both serotonin and norepinephrine transporters: II. Behavioral profile in comparison with venlafaxine, reboxetine, citalopram, and clomipramine.

1 reference

12 December 2020

Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs

1 reference

12 December 2020

'New' and 'old' antidepressants: all equal in the eyes of the lore?

1 reference

12 December 2020

Tricyclic antidepressants: Effects on the firing rate of brain noradrenergic neurons

1 reference

12 December 2020

Acute and chronic effects of desipramine and clorgyline on alpha(2)-adrenoceptors regulating noradrenergic transmission in the rat brain: a dual-probe microdialysis study

1 reference

12 December 2020

Infusion of brain-derived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus

1 reference

12 December 2020

Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication

1 reference

12 December 2020

Effects of noradrenergic activity on temporal information processing in humans

1 reference

12 December 2020

Lack of effect of reboxetine on cardiac repolarization

1 reference

12 December 2020

The effects of reboxetine on autonomic and cognitive functions in healthy volunteers

1 reference

12 December 2020

Theta oscillations in the hippocampus

1 reference

12 December 2020

Effects of reboxetine on Hamilton Depression Rating Scale factors from randomized, placebo-controlled trials in major depression

1 reference

12 December 2020

Neurobiology of depression

1 reference

12 December 2020

Delayed pharmacological effects of antidepressants

1 reference

12 December 2020

Frontal theta activity in humans increases with memory load in a working memory task

1 reference

12 December 2020

Effect of reboxetine on depression in Parkinson's disease patients.

1 reference

12 December 2020

Sequential catecholamine and serotonin depletion in mirtazapine-treated depressed patients.

1 reference

12 December 2020

Stress and depression: possible links to neuron death in the hippocampus

1 reference

12 December 2020

Effects of acute and chronic reboxetine treatment on stress-induced monoamine efflux in the rat frontal cortex

1 reference

12 December 2020

Differential modulation of efficiency in a food-rewarded "differential reinforcement of low-rate" 72-s schedule in rats by norepinephrine and serotonin reuptake inhibitors

1 reference

12 December 2020

Reboxetine: functional inhibition of monoamine transporters and nicotinic acetylcholine receptors

1 reference

12 December 2020

Reboxetine, a new noradrenaline selective antidepressant, is at least as effective as fluoxetine in the treatment of depression

1 reference

12 December 2020

The role of noradrenaline and selective noradrenaline reuptake inhibition in depression

1 reference

12 December 2020

Convergent excitation of dorsal raphe serotonin neurons by multiple arousal systems (orexin/hypocretin, histamine and noradrenaline).

1 reference

12 December 2020

The efficacy of reboxetine in the treatment-refractory patients with panic disorder: an open label study

1 reference

12 December 2020

Noradrenaline reuptake inhibition enhances the antipsychotic-like effect of raclopride and potentiates D2-blockage-induced dopamine release in the medial prefrontal cortex of the rat.

1 reference

12 December 2020

Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder

1 reference

12 December 2020

Reboxetine versus paroxetine versus placebo: effects on cognitive functioning in depressed patients

1 reference

12 December 2020

Comparison of the effects of antidepressants on norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis study

1 reference

12 December 2020

Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.

1 reference

12 December 2020

Rapid habituation of hippocampal serotonin and norepinephrine release and anxiety-related behaviors, but not plasma corticosterone levels, to repeated footshock stress in rats

1 reference

12 December 2020

Norepinephrine-gamma-aminobutyric acid (GABA) interaction in limbic stress circuits: effects of reboxetine on GABAergic neurons

1 reference

12 December 2020

Changes in human in vivo serotonin and dopamine transporter availabilities during chronic antidepressant administration

1 reference

12 December 2020

Norepinephrine but not serotonin reuptake inhibitors enhance theta and gamma activity of the septo-hippocampal system

1 reference

12 December 2020

Influence of reboxetine on salivary MHPG concentration and cognitive symptoms among patients with alcohol-related Korsakoff's syndrome

1 reference

12 December 2020

A microdialysis study of the regulation of endogenous noradrenaline release in the rat hippocampus

1 reference

12 December 2020

Comparison of the disposition and of the metabolic pattern of Reboxetine, a new antidepressant, in the rat, dog, monkey and man.

1 reference

12 December 2020

Feedback Inhibition of Brain Noradrenaline Neurons by Tricyclic Antidepressants: α-Receptor Mediation

1 reference

12 December 2020

The automated Tail Suspension Test: a computerized device which differentiates psychotropic drugs.

1 reference

12 December 2020

Is the forced swimming test a suitable model for revealing antidepressant activity?

1 reference

12 December 2020

Interactions between clonidine and antidepressant drugs: a method for identifying antidepressant-like agents

1 reference

12 December 2020

Differential-reinforcement-of-low-rate 72-second schedule: selective effects of antidepressant drugs.

1 reference

12 December 2020

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

1 reference

12 December 2020

Pharmacokinetics of reboxetine in healthy volunteers. Single oral doses, linearity and plasma protein binding

1 reference

12 December 2020

Gamma (40-100 Hz) oscillation in the hippocampus of the behaving rat

1 reference

12 December 2020

The use of tryptophan depletion to evaluate central serotonin function in depression and other neuropsychiatric disorders.

1 reference

12 December 2020

Evidence that extracellular concentrations of dopamine are regulated by noradrenergic neurons in the frontal cortex of rats

1 reference

12 December 2020

Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo

1 reference

12 December 2020

Cyclic adenosine 3',5'-monophosphate response element binding protein (CREB) and related transcription-activating deoxyribonucleic acid-binding proteins

1 reference

12 December 2020

Noradrenergic modulation of midbrain dopamine cell firing elicited by stimulation of the locus coeruleus in the rat

1 reference

12 December 2020

Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes

1 reference

12 December 2020

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.

1 reference

12 December 2020

Pharmacokinetics of reboxetine in healthy volunteers. Single against repeated oral doses and lack of enzymatic alterations

1 reference

12 December 2020

Efficacy and tolerability of reboxetine compared with imipramine in a double-blind study in patients suffering from major depressive offsodes

1 reference

12 December 2020

Do noradrenaline and serotonin differentially affect social motivation and behaviour?

1 reference

12 December 2020

Transcriptional regulation by cyclic AMP.

1 reference

12 December 2020

Modulation of forebrain electroencephalographic activity and behavioral state by the locus ceruleus-noradrenergic system: involvement of the medial septal area

1 reference

12 December 2020

Activation of the locus ceruleus brain noradrenergic system during stress: circuitry, consequences, and regulation

1 reference

12 December 2020

Brainstem-diencephalo-septohippocampal systems controlling the theta rhythm of the hippocampus.

1 reference

12 December 2020

Noradrenaline-selective versus serotonin-selective antidepressant therapy: differential effects on social functioning

1 reference

12 December 2020

Reboxetine: a review of antidepressant tolerability.

1 reference

12 December 2020

Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test

1 reference

12 December 2020

Regulation of extracellular dopamine by the norepinephrine transporter

1 reference

12 December 2020

The role of locus coeruleus in the regulation of cognitive performance

1 reference

12 December 2020

Consequences of 5-HT re-uptake blockade on postsynaptic 5-HT1A receptor activation: an electrophysiological and neurochemical study in guinea pig dorsal raphe and hippocampus

1 reference

12 December 2020

Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.

1 reference

12 December 2020

10.1111/J.1527-3458.2004.TB00002.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978512%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14978512%20AND%20SRC:MED&resulttype=core&format=json

24 November 2019

PubMed publication ID

14978512

1 reference