Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth (Q33976179)

30 July 2017

title

Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth (English)

1 reference

30 July 2017

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Indira Jutooru

1

1 reference

30 July 2017

Gayathri Chadalapaka

2

1 reference

30 July 2017

Sandeep Sreevalsan

3

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30 July 2017

Ping Lei

4

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30 July 2017

Rola Barhoumi

5

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30 July 2017

Robert Burghardt

6

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30 July 2017

Stephen Safe

7

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30 July 2017

language of work or name

English

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publication date

8 May 2010

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Experimental Cell Research

30 July 2017

published in

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30 July 2017

volume

316

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30 July 2017

issue

13

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30 July 2017

page(s)

2174-2188

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Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells

30 July 2017

cites work

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5 July 2018

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Reactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosis

5 July 2018

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Arsenic trioxide enhances the therapeutic efficacy of radiation treatment of oral squamous carcinoma while protecting bone

5 July 2018

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Curcumin decreases specificity protein expression in bladder cancer cells

5 July 2018

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The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells

5 July 2018

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The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells.

5 July 2018

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Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide

5 July 2018

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5 July 2018

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Arsenic trioxide-mediated growth inhibition in gallbladder carcinoma cells via down-regulation of Cyclin D1 transcription mediated by Sp1 transcription factor

5 July 2018

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Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors

5 July 2018

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Downregulation of transcription factor, Sp1, during cellular senescence

5 July 2018

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Inhibitory effect of arsenic trioxide on angiogenesis and expression of vascular endothelial growth factor in gastric cancer

5 July 2018

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Synergistic induction of apoptosis by sulindac and arsenic trioxide in human lung cancer A549 cells via reactive oxygen species-dependent down-regulation of survivin

5 July 2018

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Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation

5 July 2018

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5 July 2018

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Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines

5 July 2018

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Regulation of vascular endothelial growth factor receptor-2 expression in pancreatic cancer cells by Sp proteins

5 July 2018

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Mitogen-activated protein kinases mediate arsenic-induced down-regulation of survivin in human lung adenocarcinoma cells

5 July 2018

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Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins

5 July 2018

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Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation.

5 July 2018

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Neovascularization and angiogenic gene expression following chronic arsenic exposure in mice

5 July 2018

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5 July 2018

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Arsenic trioxide represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60.

5 July 2018

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Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer.

5 July 2018

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The inhibition of growth and angiogenesis in heterotransplanted esophageal carcinoma via intratumoral injection of arsenic trioxide

5 July 2018

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Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

5 July 2018

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Regulation of the activity of Sp1-related transcription factors.

5 July 2018

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5 July 2018

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Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells

5 July 2018

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Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis

5 July 2018

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The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells

5 July 2018

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Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells

5 July 2018

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Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations

5 July 2018

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Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis

5 July 2018

1 reference

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Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900380

Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900380

Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900380

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900380

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells

5 July 2018

1 reference

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In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

5 July 2018

1 reference

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Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17

5 July 2018

1 reference

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900380

Sp1 DNA binding efficiency is highly reduced in nuclear extracts from aged rat tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900380

Association between expression of transcription factor Sp1 and increased vascular endothelial growth factor expression, advanced stage, and poor survival in patients with resected gastric cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900380

Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore

29 October 2018

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.027

Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.027

Arsenic trioxide, a novel mitochondriotoxic anticancer agent?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2010.04.027

Arsenic stimulates angiogenesis and tumorigenesis in vivo

7 January 2021

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Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20435036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.YEXCR.2010.04.027

1 reference

30 July 2017

1 reference

30 July 2017

1 reference