A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A (Q33976501)

30 July 2017

A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2A (English)

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30 July 2017

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G P Shouse

1

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30 July 2017

Y Nobumori

series ordinal

2

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30 July 2017

X Liu

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

17 May 2010

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30 July 2017

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29

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3933-3941

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27

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https://scigraph.springernature.com/pub.10.1038/onc.2010.161

30 July 2017

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cites work

Modes of p53 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Blinded by the Light: The Growing Complexity of p53

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

From promiscuity to precision: protein phosphatases get a makeover

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Serine 15 phosphorylation of p53 directs its interaction with B56gamma and the tumor suppressor activity of B56gamma-specific protein phosphatase 2A

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

The glycine 90 to aspartate alteration in the Abeta subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Post-translational modification of p53 in tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Role of serine/threonine protein phosphatase 2A in cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Alterations of the PPP2R1B gene in human lung and colon cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

Identification of specific PP2A complexes involved in human cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

Recent Natural Selection Identifies a Genetic Variant in a Regulatory Subunit of Protein Phosphatase 2A that Associates with Altered Cancer Risk and Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

A specific PP2A regulatory subunit, B56gamma, mediates DNA damage-induced dephosphorylation of p53 at Thr55

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

Structure of the protein phosphatase 2A holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

Protein phosphatase 2A regulatory subunits and cancer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900437

Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity

29 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.161

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.161

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Dimensions Publication ID

30 July 2017

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30 July 2017

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