The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents. (Q33978099)

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English	The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.	scientific article

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1 November 2019

The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents (English)

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1 November 2019

Candida glabrata

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Dominique Sanglard

1

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F Ischer

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D Calabrese

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P A Majcherczyk

4

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J Bille

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1 November 1999

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Antimicrobial Agents and Chemotherapy

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43

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11

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2753-2765

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1 November 2019

Resistance of clinically important yeasts to antifungal agents

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Multiple resistance mechanisms to azole antifungals in yeast clinical isolates.

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Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans

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Distinct patterns of gene expression associated with development of fluconazole resistance in serial candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis

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5 July 2018

Fluconazole resistance associated with drug efflux and increased transcription of a drug transporter gene, PDH1, in Candida glabrata

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ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p

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Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents

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Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter.

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Dynamics of Candida isolations from humans from 1992-1995 in Greifswald, Germany.

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Molecular biological characterization of an azole-resistant Candida glabrata isolate

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5 July 2018

Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus

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5 July 2018

Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance

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5 July 2018

Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole, and candida infections. Subcommittee on Antifungal Susceptibility Te

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Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.

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Isolation and characterization of fluconazole- and amphotericin B-resistant Candida albicans from blood of two patients with leukemia

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Isolation of a Candida glabrata centromere and its use in construction of plasmid vectors.

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5 July 2018

Reduced accumulation of drug in Candida krusei accounts for itraconazole resistance

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5 July 2018

Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors

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Techniques for investigation of an apparent outbreak of infections with Candida glabrata

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Multiple Pdr1p/Pdr3p binding sites are essential for normal expression of the ATP binding cassette transporter protein-encoding gene PDR5.

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Deletion of the Candida glabrata ERG3 and ERG11 genes: effect on cell viability, cell growth, sterol composition, and antifungal susceptibility

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Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

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Fluconazole resistance in Candida glabrata

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Resistance of Candida albicans to fluconazole during treatment of oropharyngeal candidiasis in a patient with AIDS: documentation by in vitro susceptibility testing and DNA subtype analysis.

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Detection of amphotericin B-resistant Candida isolates in a broth-based system

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Antifungal susceptibility testing of isolates from a randomized, multicenter trial of fluconazole versus amphotericin B as treatment of nonneutropenic patients with candidemia. NIAID Mycoses Study Group and the Candidemia Study Group

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Resistance of Candida species to fluconazole

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29 October 2018

Antifungal drug resistance in pathogenic fungi

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29 October 2018

Post-mortem findings in patients with repeatedly mycological demonstration of Candida glabrata

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29 October 2018

National epidemiology of mycoses survey: a multicenter study of strain variation and antifungal susceptibility among isolates of Candida species

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Selection of Candida glabrata strains with reduced susceptibility to azoles in four liver transplant patients with invasive candidiasis.

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The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance

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based on heuristic

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The epidemiology of hematogenous candidiasis caused by different Candida species

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between in vitro susceptibility of Candida albicans and fluconazole-resistant oropharyngeal candidiasis in HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/10543759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clustered amino acid substitutions in the yeast transcription regulator Pdr3p increase pleiotropic drug resistance and identify a new central regulatory domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10543759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA macrorestriction profiles and antifungal susceptibility of Candida (Torulopsis) glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/10543759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluconazole susceptibility and strain variation of Candida albicans isolates from HIV-infected patients with oropharyngeal candidosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10543759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Persistence and variability of yeasts isolated from hospitalized patients: a comparison of results from Rostock and Dresden]

1 reference

https://pubmed.ncbi.nlm.nih.gov/10543759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to fluconazole and amphotericin in Candida albicans from AIDS patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/10543759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and phenotypic characterization of yeast PDR1 mutants that show hyperactive transcription of various ABC multidrug transporter genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10543759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and verification of fingerprinting probes for Candida glabrata

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition and interaction of cytochrome P450 of Candida krusei with azole antifungal drugs

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida glabrata: in vitro susceptibility of 84 isolates to eight antifungal agents

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.43.11.2753

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1 November 2019

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Europe PubMed Central

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1 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10543759%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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