Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori. (Q33980234)

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scientific article published in August 2000

Language	Label	Description	Also known as
English	Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori.	scientific article published in August 2000

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scholarly article

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8 November 2019

Analysis of rdxA and involvement of additional genes encoding NAD(P)H flavin oxidoreductase (FrxA) and ferredoxin-like protein (FdxB) in metronidazole resistance of Helicobacter pylori (English)

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8 November 2019

Helicobacter pylori

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inferred from title

6

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8 November 2019

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D H Kwon

1

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8 November 2019

F A El-Zaatari

2

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8 November 2019

M Kato

3

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8 November 2019

M S Osato

4

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8 November 2019

R Reddy

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8 November 2019

D Y Graham

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8 November 2019

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1 August 2000

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8 November 2019

Antimicrobial Agents and Chemotherapy

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8 November 2019

44

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8 November 2019

8

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8 November 2019

2133-2142

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A systematic review of Helicobacter pylori eradication therapy--the impact of antimicrobial resistance on eradication rates

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Helicobacter pylori porCDAB and oorDABC genes encode distinct pyruvate:flavodoxin and 2-oxoglutarate:acceptor oxidoreductases which mediate electron transport to NADP

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The complete genome sequence of the gastric pathogen Helicobacter pylori

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Isolation of a genetic locus associated with metronidazole resistance in Helicobacter pylori.

1 reference

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5 July 2018

Heterogeneity in susceptibility to metronidazole among Helicobacter pylori isolates from patients with gastritis or peptic ulcer disease.

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5 July 2018

Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with resistance

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Nitroimidazole drugs--action and resistance mechanisms. II. Mechanisms of resistance

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Nucleotide sequence and mutational analysis indicate that two Helicobacter pylori genes encode a P-type ATPase and a cation-binding protein associated with copper transport

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Identification of carboxylation enzymes and characterization of a novel four-subunit pyruvate:flavodoxin oxidoreductase from Helicobacter pylori

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Comparison of agar based media for primary isolation of Helicobacter pylori

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Role of the phosphoroclastic reaction of Clostridium pasteurianum in the reduction of metronidazole

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Construction of isogenic urease-negative mutants of Helicobacter pylori by allelic exchange

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Antitrichomonad action, mutagenicity, and reduction of metronidazole and other nitroimidazoles

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The influence of in vitro nitroimidazole resistance on the efficacy of nitroimidazole-containing anti-Helicobacter pylori regimens: a meta-analysis

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Demonstration of unexpected antibiotic resistance of genotypically identical Helicobacter pylori isolates.

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29 October 2018

Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase.

1 reference

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Antibiotic resistance in Helicobacter pylori infection

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Flavodoxin-dependent pyruvate oxidation, acetate production and metronidazole reduction by Helicobacter pylori

1 reference

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Antimicrobial resistance in Helicobacter pylori: a global overview

1 reference

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Pretreatment antibiotic resistance in Helicobacter pylori infection: results of three randomized controlled studies

1 reference

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12 December 2020

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The role of the rdxA gene in the evolution of metronidazole resistance in Helicobacter pylori

1 reference

https://pubmed.ncbi.nlm.nih.gov/10898687

12 December 2020

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The selective toxicity of antimicrobial nitroheterocyclic drugs

1 reference

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Mode of action of metronidazole on anaerobic bacteria and protozoa

1 reference

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Base specific interaction of reductively activated nitroimidazoles with DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/10898687

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In vitro reductive activation of nitroimidazoles

1 reference

https://pubmed.ncbi.nlm.nih.gov/10898687

12 December 2020

based on heuristic

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Mechanism of reductive activation of a 5-nitroimidazole by flavoproteins: model studies with dithionite

1 reference

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Proposed mechanism for metronidazole resistance in Helicobacter pylori

1 reference

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Antimicrobial susceptibility testing of Helicobacter pylori. Comparison of E-test, broth microdilution, and disk diffusion for ampicillin, clarithromycin, and metronidazole

1 reference

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Oxygen scavenging, NADH oxidase and metronidazole resistance in Helicobacter pylori

1 reference

https://pubmed.ncbi.nlm.nih.gov/10898687

12 December 2020

based on heuristic

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Helicobacter pylori

1 reference

https://pubmed.ncbi.nlm.nih.gov/10898687

12 December 2020

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Identifiers

10.1128/AAC.44.8.2133-2142.2000

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8 November 2019

release_ugppvjo4a5hhzkux7lah2yprje

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24 November 2022

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mapped directly with Wikidata item

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8 November 2019

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8 November 2019

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