Selective targeting of topoisomerase IV and DNA gyrase in Staphylococcus aureus: different patterns of quinolone-induced inhibition of DNA synthesis (Q33980255)

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scientific article published in August 2000

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English	Selective targeting of topoisomerase IV and DNA gyrase in Staphylococcus aureus: different patterns of quinolone-induced inhibition of DNA synthesis	scientific article published in August 2000

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10898691%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Selective targeting of topoisomerase IV and DNA gyrase in Staphylococcus aureus: different patterns of quinolone-induced inhibition of DNA synthesis (English)

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8 November 2019

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Staphylococcus aureus

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8 November 2019

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B Fournier

1

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8 November 2019

T Lu

3

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8 November 2019

K Drlica

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8 November 2019

D C Hooper

5

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8 November 2019

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1 August 2000

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8 November 2019

Antimicrobial Agents and Chemotherapy

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8 November 2019

44

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8 November 2019

8

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8 November 2019

2160-2165

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8 November 2019

Action of quinolones against Staphylococcus aureus topoisomerase IV: basis for DNA cleavage enhancement.

1 reference

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5 July 2018

Mechanism of fluoroquinolone action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Activities of trovafloxacin compared with those of other fluoroquinolones against purified topoisomerases and gyrA and grlA mutants of Staphylococcus aureus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Effect of fluoroquinolone concentration on selection of resistant mutants of Mycobacterium bovis BCG and Staphylococcus aureus

1 reference

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5 July 2018

Primary targets of fluoroquinolones in Streptococcus pneumoniae.

1 reference

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5 July 2018

DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae.

1 reference

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5 July 2018

Topoisomerase mutations in trovafloxacin-resistant Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Effects of mutations in GrlA of topoisomerase IV from Staphylococcus aureus on quinolone and coumarin activity

1 reference

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5 July 2018

Killing of Staphylococcus aureus by C-8-methoxy fluoroquinolones

1 reference

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5 July 2018

Mutations in topoisomerase IV and DNA gyrase of Staphylococcus aureus: novel pleiotropic effects on quinolone and coumarin activity

1 reference

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5 July 2018

DNA topoisomerase targets of the fluoroquinolones: a strategy for avoiding bacterial resistance

1 reference

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5 July 2018

DNA gyrase, topoisomerase IV, and the 4-quinolones

1 reference

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5 July 2018

Increased expression of fibronectin-binding proteins by fluoroquinolone-resistant Staphylococcus aureus exposed to subinhibitory levels of ciprofloxacin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Differential behaviors of Staphylococcus aureus and Escherichia coli type II DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Quinolone resistance mutations in topoisomerase IV: relationship to the flqA locus and genetic evidence that topoisomerase IV is the primary target and DNA gyrase is the secondary target of fluoroquinolones in Staphylococcus aureus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Topoisomerase IV is a target of quinolones in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Analysis of gyrA and grlA mutations in stepwise-selected ciprofloxacin-resistant mutants of Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Confirmation of protoplast fusion-derived linkages in Staphylococcus aureus by transformation with protoplast DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Differential effects of antibiotics inhibiting gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

DNA gyrase on the bacterial chromosome: possibility of two levels of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Mechanism of Action of Nalidixic Acid on Escherichia coli III. Conditions Required for Lethality

1 reference

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5 July 2018

Studies on plasmid replication. I. Plasmid incompatibility and establishment in Staphylococcus aureus

1 reference

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5 July 2018

Association between early inhibition of DNA synthesis and the MICs and MBCs of carboxyquinolone antimicrobial agents for wild-type and mutant [gyrA nfxB(ompF) acrA] Escherichia coli K-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Mechanisms of action of and resistance to ciprofloxacin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90029

5 July 2018

Rapid development of ciprofloxacin resistance in methicillin-susceptible and -resistant Staphylococcus aureus.

1 reference

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5 July 2018

A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus

1 reference

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Survival of recombination-deficient mutants of Escherichia coli during incubation with nalidixic acid

1 reference

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DNA gyrase on the bacterial chromosome: DNA cleavage induced by oxolinic acid

1 reference

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Sedimentation analysis of bacterial nucleoid structure

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The mechanism of inhibition of topoisomerase IV by quinolone antibacterials

1 reference

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DNA strand cleavage is required for replication fork arrest by a frozen topoisomerase-quinolone-DNA ternary complex.

1 reference

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DNA gyrase and topoisomerase IV on the bacterial chromosome: quinolone-induced DNA cleavage.

1 reference

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1 reference

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29 October 2018

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10898691

12 December 2020

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10.1128/AAC.44.8.2160-2165.2000

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8 November 2019

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8 November 2019

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8 November 2019

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