PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets. (Q33981871)

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6 February 2020

title

PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets (English)

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6 February 2020

7

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6 February 2020

Robert N. Fariss

17

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6 February 2020

J. Silvio Gutkind

20

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13

Sagarika Chakrabarty

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6 February 2020

author name string

Xu Hou

1

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6 February 2020

Anil Kumar

2

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6 February 2020

Chunsik Lee

3

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6 February 2020

Bin Wang

4

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6 February 2020

Pachiappan Arjunan

5

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Lijin Dong

6

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6 February 2020

Zhongshu Tang

8

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6 February 2020

Yang Li

9

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6 February 2020

Fan Zhang

10

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6 February 2020

Shi-Zhuang Zhang

11

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Piotr Wardega

12

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Baoying Liu

14

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6 February 2020

Zhijian Wu

15

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Peter Colosi

16

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Johan Lennartsson

18

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Yihai Cao

21

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Xuri Li

22

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Robert Nussenblatt

19

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language of work or name

English

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publication date

21 June 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566880%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

6 February 2020

published in

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volume

107

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issue

27

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6 February 2020

page(s)

12216-12221

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Pathways mediating VEGF-independent tumor angiogenesis

6 February 2020

cites work

1 reference

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Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies

5 July 2018

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Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.

5 July 2018

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VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

5 July 2018

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Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.

5 July 2018

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Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts

5 July 2018

1 reference

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PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment

5 July 2018

1 reference

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Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression

5 July 2018

1 reference

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Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

5 July 2018

1 reference

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R Regulation of tumor angiogenesis and metastasis by FGF and PDGF signaling pathways

5 July 2018

1 reference

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VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma

5 July 2018

1 reference

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Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors

5 July 2018

1 reference

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A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling

5 July 2018

1 reference

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Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

5 July 2018

1 reference

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Angiogenesis stimulated by PDGF-CC, a novel member in the PDGF family, involves activation of PDGFR-alphaalpha and -alphabeta receptors

5 July 2018

1 reference

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PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor

5 July 2018

1 reference

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A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF.

5 July 2018

1 reference

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Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

5 July 2018

1 reference

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Imatinib buys time for brain after stroke

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004143107

PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004143107

Comparative evaluation of apoptotic activity in photoreceptor cells after intravitreal injection of bevacizumab and pegaptanib sodium in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004143107

Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004143107

Testing intravitreal toxicity of bevacizumab (Avastin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004143107

Akt regulates the survival of vascular smooth muscle cells via inhibition of FoxO3a and GSK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004143107

Platelet-Derived Growth Factor CC — A Clinically Useful Angiogenic Factor at Last?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1004143107

A new member of an old family

21 January 2018

1 reference

12 December 2020

A potential role for PDGF-C in experimental and clinical proliferative vitreoretinopathy

1 reference

12 December 2020

Ultrastructural findings in the primate eye after intravitreal injection of bevacizumab

1 reference

12 December 2020

Tumor-associated fibroblasts as "Trojan Horse" mediators of resistance to anti-VEGF therapy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1004143107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566880%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566880%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

20566880

1 reference