Role of thymidylate synthetase activity in development of methotrexate cytotoxicity (Q33982869)

30 July 2017

title

Role of thymidylate synthetase activity in development of methotrexate cytotoxicity (English)

1 reference

30 July 2017

0 references

1 reference

R. G. Moran

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A160558

18 December 2022

M. Mulkins

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A160558

18 December 2022

C. Heidelberger

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A160558

18 December 2022

language of work or name

English

0 references

publication date

1 November 1979

1 reference

full work available at URL

30 July 2017

https://europepmc.org/articles/PMC411765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A160558

https://europepmc.org/articles/PMC411765?pdf=render

18 December 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A160558

https://pnas.org/doi/pdf/10.1073/pnas.76.11.5924

18 December 2022

1 reference

Crossref

DOI

10.1073/PNAS.76.11.5924

https://api.crossref.org/works/10.1073/PNAS.76.11.5924

Proceedings of the National Academy of Sciences of the United States of America

18 December 2022

published in

1 reference

30 July 2017

volume

76

1 reference

30 July 2017

issue

11

1 reference

30 July 2017

page(s)

5924-5928

1 reference

CONTINUOUS CULTURE OF HUMAN LYMPHOBLASTS FROM PERIPHERAL BLOOD OF A CHILD WITH ACUTE LEUKEMIA.

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Studies on the identification of a folate compound of human serum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Regulation of Mammalian Deoxyribonucleotide Biosynthesis by Nucleotides as Activators and Inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Pyrimidine metabolism in microorganisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Changes of molecular properties associated with the development of resistance against methotrexate in human lymphoblastoid cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Mechanism of growth inhibition by methotrexate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Methotrexate and the need for continued research

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

The prevention of methotrexate toxicity by thymidine infusions in humans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Schedule-dependent antitumor effects of methotrexate and 5-fluorouracil

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Competitive protein binding assay for methotrexate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

A basis for fluoropyrimidine-induced antagonism to methotrexate in Ehrlich ascites tumor cells in vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Reactivation of dihydrofolate reductase inhibited by methotrexate or aminopterin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Human thymidylate synthetase derived from blast cells of patients with acture myelocytic leukemia. Purification and chracterization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

The regulation of thymidylate biosynthesis in Novikoff hepatoma cells and the effects of amethopterin, 5-fluorodeoxyuridine, and 3-deazauridine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Methotrexate inhibition of CCRF-CEM cultures of human lymphoblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Biochemical determinants of tumor sensitivity to 5-fluorouracil: Ultrasensitive methods for the determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthetase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Intrinsic resistance to methotrexate of cultured mammalian cells in relation to the inhibition kinetics of their dihydrololate reductases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

AGAR SUSPENSION CULTURE FOR THE SELECTIVE ASSAY OF CELLS TRANSFORMED BY POLYOMA VIRUS.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Tetrahydrofolate-dependent enzymes in Sarcoma 180 cells sensitive and resistant to amethopterin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

Studies relating to the mode of action of methotrexate. II. Studies on sites of action in L-cells in vitro

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=411765

The reversal of methotrexate toxicity by thymidine with maintenance of antitumour effects

29 October 2018

1 reference

12 December 2020

The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides

1 reference

12 December 2020

Effects of allopurinol on the therapeutic efficacy of methotrexate

1 reference

12 December 2020

Prevention of toxicity of amethopterin for sarcoma-180 cells in tissue culture

1 reference

12 December 2020

The ability of purine and thymine derivatives and of glycine to support the growth of mammalian cells in culture

1 reference

12 December 2020

On the nature of a sparing effect by thymidine on the utilization of deoxycytidine

1 reference

12 December 2020

Studies on the folate compounds of human blood

1 reference

12 December 2020

STUDIES ON THE INHIBITION OF DIHYDROFOLATE REDUCTASE BY THE FOLATE ANTAGONISTS

1 reference

12 December 2020

The turnover of folate coenzymes in murine lymphoma cells

1 reference

12 December 2020

Interaction of drugs inhibiting different steps in the synthesis of DNA

1 reference

12 December 2020

Combination chemotherapy: The interaction of methotrexate and 5-fluorouracil

1 reference

12 December 2020

Studies relating to the mode of action of methotrexate. 3. Inhibition of thymidylate synthetase in tissue culture cells and in cell-free systems

1 reference

12 December 2020

Purineless death as a link between growth rate and cytotoxicity by methotrexate

1 reference

12 December 2020

Growth rate and cell kill

1 reference

12 December 2020

Liver Disease Associated With Methotrexate Treatment of Psoriatic Patients

1 reference

12 December 2020

Cell killing studies on the mode of action of methotrexate on L-cells in vitro

1 reference

12 December 2020

Naturally occurring folates in the blood and liver of the rat

1 reference

12 December 2020

Deoxycytidylate Aminohydrolase. II. Kinetic Properties. The Activatory Effect of Deoxycytidine Triphosphate and the Inhibitory Effect of Deoxythymidine Triphosphate*

1 reference

12 December 2020

The purification and properties of thymidylate synthetase from chick embryo extracts

1 reference

12 December 2020

Deoxycytidylate Aminohydrolase. III. Modifications of the Substrate Sites Caused by Allosteric Effectors*

1 reference

12 December 2020

Potentiation of the antitumor activity of methotrexate by concurrent infusion of thymidine

1 reference

12 December 2020

Inhibition of growth rate and deoxynucleoside triphosphate concentrations in cultured leukemia L1210 cells

1 reference

12 December 2020

Folate metabolism in mammalian cells in culture. I Partial characterization of the folate derivatives present in L1210 mouse leukemia cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.76.11.5924

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference