Pharmacokinetic interactions between nelfinavir and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors atorvastatin and simvastatin (Q33983600)

30 July 2017

Pharmacokinetic interactions between nelfinavir and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors atorvastatin and simvastatin (English)

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30 July 2017

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P H Hsyu

1

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30 July 2017

M D Schultz-Smith

2

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30 July 2017

J H Lillibridge

3

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30 July 2017

R H Lewis

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30 July 2017

B M Kerr

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30 July 2017

language of work or name

English

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publication date

1 December 2001

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Antimicrobial Agents and Chemotherapy

30 July 2017

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30 July 2017

45

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30 July 2017

3445-3450

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30 July 2017

12

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HMG-CoA reductase inhibitors (statins) characterized as direct inhibitors of P-glycoprotein

30 July 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Circulating metabolites of the human immunodeficiency virus protease inhibitor nelfinavir in humans: structural identification, levels in plasma, and antiviral activities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

HMG-CoA reductase inhibitors and P-glycoprotein modulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Myolysis and acute renal failure in a heart-transplant recipient receiving lovastatin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=90851

FDA warns of potential protease-inhibitor link to hyperglycaemia

29 October 2018

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12 December 2020

Comparison of pravastatin and lovastatin in renal transplant patients receiving cyclosporine

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12 December 2020

New-onset diabetes mellitus associated with use of protease inhibitor

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12 December 2020

Visceral abdominal-fat accumulation associated with use of indinavir

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12 December 2020

Antiretroviral therapy for HIV infection in 1998: updated recommendations of the International AIDS Society-USA Panel

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12 December 2020

Disorders of fat distribution in HIV infection

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12 December 2020

Atorvastatin for protease inhibitor-related hyperlipidaemia

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12 December 2020

Plasma concentration profiles of simvastatin 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin

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12 December 2020

Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid

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12 December 2020

Drug-interaction-induced rhabdomyolysis

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12 December 2020

Multiple-dose pharmacokinetics, pharmacodynamics, and safety of atorvastatin, an inhibitor of HMG-CoA reductase, in healthy subjects

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12 December 2020

Impact of combination therapy for HIV infection on inpatient census

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12 December 2020

10.1128/AAC.45.12.3445-3450.2001

Identifiers

DOI

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30 July 2017

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30 July 2017

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