Recombinant VP1, an Akt inhibitor, suppresses progression of hepatocellular carcinoma by inducing apoptosis and modulation of CCL2 production (Q33986185)

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English	Recombinant VP1, an Akt inhibitor, suppresses progression of hepatocellular carcinoma by inducing apoptosis and modulation of CCL2 production	scientific article

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9 February 2020

Recombinant VP1, an Akt inhibitor, suppresses progression of hepatocellular carcinoma by inducing apoptosis and modulation of CCL2 production (English)

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9 February 2020

hepatocellular carcinoma

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inferred from title

6

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9 February 2020

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Tai-An Chen

1

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9 February 2020

Jui-Ling Wang

2

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9 February 2020

Shao-Wen Hung

3

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9 February 2020

Chiao-Li Chu

4

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9 February 2020

Yung-Chih Cheng

5

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9 February 2020

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3 August 2011

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9 February 2020

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9 February 2020

6

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9 February 2020

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9 February 2020

e23317

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9 February 2020

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Creative Commons Attribution 4.0 International

3 August 2011

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0 references

Monocyte chemoattractant protein-1 blockade inhibits lung cancer tumor growth by altering macrophage phenotype and activating CD8+ cells

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Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization

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CCR2 expression correlates with prostate cancer progression

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CCL2 (Monocyte Chemoattractant Protein-1) in cancer bone metastases

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28 July 2018

Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion.

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The survival kinases Akt and Pim as potential pharmacological targets

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28 July 2018

Transactivation of MCP-1/CCL2 by beta-catenin/TCF-4 in human breast cancer cells

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Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation

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Comparative studies of the capsid precursor polypeptide P1 and the capsid protein VP1 cDNA vectors for DNA vaccination against foot-and-mouth disease virus.

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PI3K-Akt pathway: its functions and alterations in human cancer

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Signaling to NF-kappaB

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28 July 2018

Hepatocellular carcinoma

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28 July 2018

The CC chemokine MCP-1/CCL2 in pancreatic cancer progression: regulation of expression and potential mechanisms of antimalignant activity.

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Ku70 suppresses the apoptotic translocation of Bax to mitochondria.

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Chemokine receptor CCR2 is expressed by human multiple myeloma cells and mediates migration to bone marrow stromal cell-produced monocyte chemotactic proteins MCP-1, -2 and -3.

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VP1 of foot-and-mouth disease virus induces apoptosis via the Akt signaling pathway

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Postoperative hepatitis status as a significant risk factor for recurrence in cirrhotic patients with small hepatocellular carcinoma

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Vaccination with dendritic cells pulsed with apoptotic cells elicits effective antitumor immunity in murine hepatoma models

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Downregulation of proapoptotic proteins Bax and Bcl-X(S) in p53 overexpressing hepatocellular carcinomas

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Postresection recurrence of hepatocellular carcinoma treated by arterial embolization: analysis of prognostic factors

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10.1371/JOURNAL.PONE.0023317

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9 February 2020

2011PLoSO...623317C

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9 February 2020

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9 February 2020

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