Traumatic brain injury: cause or risk of Alzheimer's disease? A review of experimental studies (Q33987844)

30 July 2017

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title

Traumatic brain injury: cause or risk of Alzheimer's disease? A review of experimental studies (English)

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30 July 2017

traumatic brain injury

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O Wirths

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Peter Falkai

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P Falkai

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author name string

J Szczygielski

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30 July 2017

A Mautes

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30 July 2017

W I Steudel

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30 July 2017

T A Bayer

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30 July 2017

15 June 2005

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Journal of Neural Transmission

30 July 2017

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30 July 2017

112

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30 July 2017

11

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30 July 2017

1547-1564

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https://scigraph.springernature.com/pub.10.1007/s00702-005-0326-0

30 July 2017

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cites work

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Assessment of white matter injury following prolonged focal cerebral ischaemia in the rat.

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Increased tau immunoreactivity in oligodendrocytes following human stroke and head injury.

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Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes.

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Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

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Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein

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Complete cerebral ischemia with short-term survival in rats induced by cardiac arrest. I. Extracellular accumulation of Alzheimer's β-amyloid protein precursor in the brain

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Brain trauma in aged transgenic mice induces regression of established abeta deposits

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12 December 2020

Amyloid precursor protein accumulates in regions of neurodegeneration following focal cerebral ischemia in the rat

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APOE epsilon4 allele and amyloid beta-protein deposition in long term survivors of head injury

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Characterization of a distinct set of intra-axonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability

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Chronic cognitive deficits and amyloid precursor protein elevation after selective immunotoxin lesions of the basal forebrain cholinergic system.

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Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury

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Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

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12 December 2020

K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus

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12 December 2020

Regulation of APP cleavage by alpha-, beta- and gamma-secretases

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12 December 2020

The direct effects of graded axonal compression on axoplasm and fast axoplasmic transport

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12 December 2020

Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.

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12 December 2020

Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.

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12 December 2020

Mild head injury increasing the brain's vulnerability to a second concussive impact.

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12 December 2020

A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

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12 December 2020

Molecular pathology of head trauma: altered beta APP metabolism and the aetiology of Alzheimer's disease.

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12 December 2020

Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease

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12 December 2020

A mechanistic analysis of nondisruptive axonal injury: a review

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12 December 2020

Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

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12 December 2020

β-Amyloid precursor protein gene is differentially expressed in axotomized sensory and motor systems

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12 December 2020

Changes in expression of amyloid precursor protein and interleukin-1beta after experimental traumatic brain injury in rats.

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12 December 2020

Early detection of axonal injury after human head trauma using immunocytochemistry for beta-amyloid precursor protein.

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12 December 2020

Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig.

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12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

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12 December 2020

Post-ischemic changes in the expression of Alzheimer's APP isoforms in rat cerebral cortex.

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12 December 2020

Detection of neuritic plaques in Alzheimer's disease by magnetic resonance microscopy

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12 December 2020

Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease

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12 December 2020

Key factors in Alzheimer's disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport

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12 December 2020

Amyloid precursor protein is synthesized by retinal ganglion cells, rapidly transported to the optic nerve plasma membrane and nerve terminals, and metabolized.

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12 December 2020

Rapid appearance of beta-amyloid precursor protein immunoreactivity in damaged axons and reactive glial cells in rat brain following needle stab injury.

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12 December 2020

Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias

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12 December 2020

Traumatic brain injury elevates the Alzheimer's amyloid peptide A beta 42 in human CSF. A possible role for nerve cell injury.

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12 December 2020

Diffuse neuronal perikaryon amyloid precursor protein immunoreactivity in a focal head impact model.

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12 December 2020

Traumatic brain injury as a risk factor for Alzheimer's disease: a review.

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12 December 2020

Imaging of amyloid-beta deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy.

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12 December 2020

Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid ?-protein and tau protein

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12 December 2020

Stalning af amyloid percursor protein to study axonal damage in mild head Injury

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12 December 2020

Microglial interleukin-1 alpha expression in human head injury: correlations with neuronal and neuritic beta-amyloid precursor protein expression

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12 December 2020

Age and damage induced changes in amyloid protein precursor immunohistochemistry in the rat brain.

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12 December 2020

The visualization of a new class of traumatically injured axons through the use of a modified method of microwave antigen retrieval

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12 December 2020

Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system.

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12 December 2020

Ultrastructural evidence of axonal shearing as a result of lateral acceleration of the head in non-human primates.

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12 December 2020

Amyloid precursor protein accumulates in white matter at the margin of a focal ischaemic lesion.

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12 December 2020

Expression of beta-amyloid precursor protein mRNAs following transient focal ischaemia.

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12 December 2020

Long-term intracerebral inflammatory response after traumatic brain injury

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12 December 2020

Tau hyperphosphorylation in apolipoprotein E-deficient and control mice after closed head injury.

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12 December 2020

Development and evaluation of iodinated tracers targeting amyloid plaques for SPECT imaging

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12 December 2020

Expression of APP in the early stage of brain damage.

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12 December 2020

Impact acceleration injury in the rat: evidence for focal axolemmal change and related neurofilament sidearm alteration.

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12 December 2020

Traumatic brain injury as a risk factor for Alzheimer's disease.

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12 December 2020

Neuropathological stageing of Alzheimer-related changes

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12 December 2020

Amyloid β accumulation in axons after traumatic brain injury in humans

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12 December 2020

Cytochemical evidence for redistribution of membrane pump calcium-ATPase and ecto-Ca-ATPase activity, and calcium influx in myelinated nerve fibres of the optic nerve after stretch injury.

1 reference

12 December 2020

Temporal and regional patterns of axonal damage following traumatic brain injury: a beta-amyloid precursor protein immunocytochemical study in rats.

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12 December 2020

Correlation of survival time with size of axonal swellings in diffuse axonal injury

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12 December 2020

Head trauma with loss of consciousness as a risk factor for Alzheimer's disease

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12 December 2020

Twofold overexpression of human beta-amyloid precursor proteins in transgenic mice does not affect the neuromotor, cognitive, or neurodegenerative sequelae following experimental brain injury.

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12 December 2020

Multiple immunostaining methods to detect traumatic axonal injury in the rat fluid-percussion brain injury model.

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12 December 2020

Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1).

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12 December 2020

βA4 amyloid protein deposition in brain after head trauma

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12 December 2020

Accumulation of amyloid precursor protein in neurons after intraventricular injection of colchicine

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12 December 2020

Neurofibrillary tangles, but not Alzheimer-type pathology, in a young boxer.

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12 December 2020

The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion

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12 December 2020

Markers of axonal injury in post mortem human brain

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12 December 2020

Amyloid beta 1-42 and tau in cerebrospinal fluid after severe traumatic brain injury

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12 December 2020

Repetitive mild brain trauma accelerates Abeta deposition, lipid peroxidation, and cognitive impairment in a transgenic mouse model of Alzheimer amyloidosis.

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12 December 2020

Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer disease.

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12 December 2020

Incidence of axonal injury in human brain tissue.

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12 December 2020

Neuronal cytoskeletal changes are an early consequence of repetitive head injury

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12 December 2020

Altered beta-APP metabolism after head injury and its relationship to the aetiology of Alzheimer's disease.

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12 December 2020

Beta-amyloid precursor protein staining of nonaccidental central nervous system injury in pediatric autopsies.

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12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

Topography of Axonal Injury as Defined by Amyloid Precursor Protein and the Sector Scoring Method in Mild and Severe Closed Head Injury

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12 December 2020

Traumatic axonal injury: practical issues for diagnosis in medicolegal cases

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12 December 2020

Traumatically induced altered membrane permeability: its relationship to traumatically induced reactive axonal change

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12 December 2020

Experimental brain injury induces expression of amyloid precursor protein, which may be related to neuronal loss in the hippocampus.

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12 December 2020

Expression of beta-amyloid precursor protein in reactive astrocytes following neuronal damage

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12 December 2020

Traumatic damage to the nodal axolemma: an early, secondary injury

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12 December 2020

Pathobiology of traumatically induced axonal injury in animals and man.

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12 December 2020

Changes in microtubule-associated protein 2 and amyloid precursor protein immunoreactivity following traumatic brain injury in rat: influence of MK-801 treatment

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12 December 2020

Beta-amyloid precursor protein immunohistochemistry in the evaluation of pediatric traumatic optic nerve injury

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12 December 2020

Post-traumatic Alzheimer's disease: preponderance of a single plaque type

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12 December 2020

Traumatic brain injury in young, amyloid-beta peptide overexpressing transgenic mice induces marked ipsilateral hippocampal atrophy and diminished Abeta deposition during aging.

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12 December 2020

The Epidemiology of Traumatic Brain Injury: A Review

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12 December 2020

Beta-amyloid precursor protein localization in the Golgi apparatus in neurons and oligodendrocytes. An immunocytochemical structural and ultrastructural study in normal and axotomized neurons

1 reference

12 December 2020

Expression of APP in brains of transgenic mice containing the entire human APP gene.

1 reference

12 December 2020

Visualization of beta-amyloid plaques in a transgenic mouse model of Alzheimer's disease using MR microscopy without contrast reagents

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12 December 2020

Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex.

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12 December 2020

Emergence of immunoreactivities for phosphorylated tau and amyloid-beta protein in chronic stage of fluid percussion injury in rat brain.

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12 December 2020

Increased numbers of beta APP-immunoreactive neurones in the entorhinal cortex after head injury

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12 December 2020

Is beta-APP a marker of axonal damage in short-surviving head injury?

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12 December 2020

The diagnosis of diffuse axonal injury: implications for forensic practice.

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12 December 2020

Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert

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12 December 2020

Topography and severity of axonal injury in human spinal cord trauma using amyloid precursor protein as a marker of axonal injury

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12 December 2020

Altered expression of amyloid precursors proteins after traumatic brain injury in rats: in situ hybridization and immunohistochemical study

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12 December 2020

Specificity and sensitivity of betaAPP in head injury

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12 December 2020

Tau immunohistochemistry in acute brain injury

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12 December 2020

Traumatic brain injury in rat produces changes of beta-amyloid precursor protein immunoreactivity

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12 December 2020

Alzheimer's amyloid precursor protein accumulates within axonal swellings in human brain lesions

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12 December 2020

Upregulation of amyloid precursor protein messenger RNA in response to traumatic brain injury: an ovine head impact model.

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12 December 2020

Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury.

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12 December 2020

Upregulation of amyloid precursor protein and its mRNA in an experimental model of paediatric head injury

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12 December 2020

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport

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12 December 2020

Redistribution of neurofilaments and accumulation of beta-amyloid protein after brain injury by rotational acceleration of the head

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12 December 2020

Real-time PCR quantitation of FE65 a β-amyloid precursor protein-binding protein after traumatic brain injury in rats

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12 December 2020

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

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12 December 2020

Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid beta-protein of Alzheimer's disease

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12 December 2020

The occult aftermath of boxing

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12 December 2020

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

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12 December 2020

Axonal injury: a universal consequence of fatal closed head injury?

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12 December 2020

Alzheimer amyloid protein precursor in the rat hippocampus: transport and processing through the perforant path

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12 December 2020

Immunohistochemical characterization of alterations in the distribution of amyloid precursor proteins and beta-amyloid peptide after experimental brain injury in the rat.

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12 December 2020

C-tau biomarker of neuronal damage in severe brain injured patients: association with elevated intracranial pressure and clinical outcome.

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12 December 2020

Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury.

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12 December 2020

10.1007/S00702-005-0326-0

Identifiers

DOI

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30 July 2017

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