Trauma hemorrhagic shock-induced lung injury involves a gut-lymph-induced TLR4 pathway in mice (Q33988264)

30 July 2017

title

Trauma hemorrhagic shock-induced lung injury involves a gut-lymph-induced TLR4 pathway in mice (English)

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30 July 2017

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13

Edwin A Deitch

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30 July 2017

Diego C Reino

1

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30 July 2017

Vadim Pisarenko

2

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30 July 2017

David Palange

3

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30 July 2017

Danielle Doucet

4

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30 July 2017

Robert P Bonitz

5

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30 July 2017

Qi Lu

6

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30 July 2017

Iriana Colorado

7

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30 July 2017

Sharvil U Sheth

8

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30 July 2017

Benjamin Chandler

9

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30 July 2017

Kolenkode B Kannan

10

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30 July 2017

Madhuri Ramanathan

11

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30 July 2017

Da Zhong Xu

12

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30 July 2017

Rena Feinman

14

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30 July 2017

language of work or name

English

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publication date

4 August 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

8

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30 July 2017

page(s)

e14829

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

4 August 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

p53 regulates renal expression of HIF-1{alpha} and pVHL under physiological conditions and after ischemia-reperfusion injury

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5 July 2018

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Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illness

5 July 2018

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Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling

5 July 2018

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The gut is a motor of organ system dysfunction

5 July 2018

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Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage.

5 July 2018

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Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages

5 July 2018

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Regulation of lung injury and repair by Toll-like receptors and hyaluronan

5 July 2018

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Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide.

5 July 2018

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Inferences, questions and possibilities in Toll-like receptor signalling

5 July 2018

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Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses.

5 July 2018

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In vitro activation of murine peritoneal macrophages by ultraviolet B radiation: upregulation of CD18, production of NO, proinflammatory cytokines and a signal transduction pathway.

5 July 2018

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5 July 2018

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Innate immune recognition

5 July 2018

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Factors larger than 100 kd in post-hemorrhagic shock mesenteric lymph are toxic for endothelial cells

5 July 2018

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Gut-derived mesenteric lymph: a link between burn and lung injury.

5 July 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

5 July 2018

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Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

5 July 2018

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Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock

5 July 2018

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A prospective randomized study of end points of resuscitation after major trauma: global oxygen transport indices versus organ-specific gastric mucosal pH

5 July 2018

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Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide

5 July 2018

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The gut origin septic states in blunt multiple trauma (ISS = 40) in the ICU.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Multiple organ failure. Pathophysiology and potential future therapy

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow-derived cells and parenchymal cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Toll-like receptor 4 contributes to microvascular inflammation and barrier dysfunction in thermal injury

29 October 2018

1 reference

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Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Cutting edge: TLR4 deficiency confers susceptibility to lethal oxidant lung injury

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

The role of lymph factors in lung injury, bone marrow suppression, and endothelial cell dysfunction in a primate model of trauma-hemorrhagic shock

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Hemorrhage-induced acute lung injury is TLR-4 dependent

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Injury primes the innate immune system for enhanced Toll-like receptor reactivity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Mesenteric lymph duct ligation provides long term protection against hemorrhagic shock-induced lung injury.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150139

Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set

29 October 2018

1 reference

12 December 2020

Increased intestinal permeability is associated with the development of multiple organ dysfunction syndrome in critically ill ICU patients

1 reference

12 December 2020

The lipid fraction of post-hemorrhagic shock mesenteric lymph (PHSML) inhibits neutrophil apoptosis and enhances cytotoxic potential

1 reference

12 December 2020

Induction of early inflammatory gene expression in a murine model of nonresuscitated, fixed-volume hemorrhage

1 reference

12 December 2020

Signaling for myocardial depression in hemorrhagic shock: roles of Toll-like receptor 4 and p55 TNF-alpha receptor

1 reference

12 December 2020

Trauma-hemorrhagic shock mesenteric lymph from rat contains a modified form of albumin that is implicated in endothelial cell toxicity

1 reference

12 December 2020

Systemic inflammation and remote organ damage following bilateral femur fracture requires Toll-like receptor 4

1 reference

12 December 2020

Gut-lymph hypothesis of systemic inflammatory response syndrome/multiple-organ dysfunction syndrome: validating studies in a porcine model

1 reference

12 December 2020

Folimycin (concanamycin A) inhibits LPS-induced nitric oxide production and reduces surface localization of TLR4 in murine macrophages

1 reference

12 December 2020

Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling

1 reference

12 December 2020

Intestinal permeability is increased in burn patients shortly after injury

1 reference

12 December 2020

Inducible nitric oxide synthase gene knockout mice have increased resistance to gut injury and bacterial translocation after an intestinal ischemia-reperfusion injury

1 reference

12 December 2020

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0014829

Identifiers

DOI

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30 July 2017

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30 July 2017

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