Delivery of ubiquitinated substrates to protein-unfolding machines (Q33989072)

30 July 2017

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title

Delivery of ubiquitinated substrates to protein-unfolding machines (English)

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30 July 2017

main subject

protein ubiquitination

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Suzanne Elsasser

1

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30 July 2017

Daniel Finley

series ordinal

2

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30 July 2017

publication date

1 August 2005

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30 July 2017

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30 July 2017

volume

7

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30 July 2017

issue

8

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30 July 2017

page(s)

742-749

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When ubiquitin meets ubiquitin receptors: a signalling connection

30 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Ubiquitin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Arabidopsis MBP1 gene encodes a conserved ubiquitin recognition component of the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Rad23 and Rpn10: perennial wallflowers join the melee

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Rad23 links DNA repair to the ubiquitin/proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Proteins containing the UBA domain are able to bind to multi-ubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Recognition of specific ubiquitin conjugates is important for the proteolytic functions of the ubiquitin-associated domain proteins Dsk2 and Rad23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Proteasome subunit Rpn1 binds ubiquitin-like protein domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Rad23 promotes the targeting of proteolytic substrates to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Involvement of the DNA repair protein hHR23 in p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

A genome-wide screen identifies Yos9p as essential for ER-associated degradation of glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Recognition of the polyubiquitin proteolytic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Rad23 ubiquitin-associated domains (UBA) inhibit 26 S proteasome-catalyzed proteolysis by sequestering lysine 48-linked polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Multiple interactions of rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The DNA damage-inducible UbL-UbA protein Ddi1 participates in Mec1-mediated degradation of Ho endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Structure and Ubiquitin Binding of the Ubiquitin-interacting Motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Structural determinants for the binding of ubiquitin-like domains to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Developmentally regulated, alternative splicing of the Rpn10 gene generates multiple forms of 26S proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Identification of ubiquitin-like protein-binding subunits of the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Uch2/Uch37 is the major deubiquitinating enzyme associated with the 26S proteasome in fission yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Sequence elements that contribute to the degradation of yeast G alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Ubiquitin-like proteins and Rpn10 play cooperative roles in ubiquitin-dependent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

UBA domains of DNA damage-inducible proteins interact with ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Proteasome-mediated degradation of cotranslationally damaged proteins involves translation elongation factor 1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of HHR23A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Localization to the proteasome is sufficient for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The Ubx2 and Ubx3 cofactors direct Cdc48 activity to proteolytic and nonproteolytic ubiquitin-dependent processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The UBX domain: a widespread ubiquitin-like module

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Evolutionary history and higher order classification of AAA+ ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Ubiquitin interactions of NZF zinc fingers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Binding of Cdc48p to a ubiquitin-related UBX domain from novel yeast proteins involved in intracellular proteolysis and sporulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Proteasomes and their kin: proteases in the machine age

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

How the ubiquitin-proteasome system controls transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Cdc48-Ufd1-Npl4: stuck in the middle with Ub.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Cdc48p is required for the cell cycle commitment point at Start via degradation of the G1-CDK inhibitor Far1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

The crystal structure of murine p97/VCP at 3.6A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Structure of the AAA ATPase p97

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

AAA ATPase p97/valosin-containing protein interacts with gp78, a ubiquitin ligase for endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Physical association of ubiquitin ligases and the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Multiple associated proteins regulate proteasome structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Multiple binding proteins suggest diverse functions for the N-ethylmaleimide sensitive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Non-traditional functions of ubiquitin and ubiquitin-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

Protein degradation: recognition of ubiquitinylated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

The DNA repair protein rad23 is a negative regulator of multi-ubiquitin chain assembly

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

Ubiquitin binding proteins protect ubiquitin conjugates from disassembly

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

Solution conformation of Lys63-linked di-ubiquitin chain provides clues to functional diversity of polyubiquitin signaling

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

p97, a protein coping with multiple identities

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FNCB0805-742

7 January 2021

Identifiers

DOI

10.1038/NCB0805-742

1 reference

Dimensions Publication ID

30 July 2017

1017758127

0 references

1 reference