Determination and stability of CP-31398 in plasma from experimental animals by LC-MS/MS. (Q33989650)

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Determination and stability of CP-31398 in plasma from experimental animals by LC-MS/MS. (English)

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Miguel Muzzio

1

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Zhihua Huang

2

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William D Johnson

3

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David L McCormick

4

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Izet M Kapetanovic

5

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22 July 2011

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6

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Journal of Pharmaceutical and Biomedical Analysis

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published in

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56

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4

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809-814

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describes a project that uses

30 July 2017

liquid chromatography–mass spectrometry

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liquid chromatography-tandem mass spectrometry

inferred from title

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Reactivation of p53: from peptides to small molecules.

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cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

Targeting wild-type and mutant p53 with small molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing reactive oxygen species-dependent apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

Mutant p53 targeting by the low molecular weight compound STIMA-1

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

Suppression of familial adenomatous polyposis by CP-31398, a TP53 modulator, in APCmin/+ mice

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3164819

Pharmacological rescue of mutant p53 conformation and function

29 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21831553

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.JPBA.2011.07.013

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30 July 2017

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