Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies (Q33997044)

30 July 2017

title

Loss of the desmosomal protein perp enhances the phenotypic effects of pemphigus vulgaris autoantibodies (English)

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30 July 2017

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pemphigus vulgaris

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Bichchau Nguyen

1

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30 July 2017

Rachel L Dusek

2

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30 July 2017

Veronica G Beaudry

3

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30 July 2017

M Peter Marinkovich

4

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30 July 2017

Laura D Attardi

5

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30 July 2017

language of work or name

English

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publication date

22 January 2009

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Journal of Investigative Dermatology

30 July 2017

published in

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30 July 2017

volume

129

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30 July 2017

issue

7

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30 July 2017

page(s)

1710-1718

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Structure and function of desmosomes

30 July 2017

cites work

1 reference

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5 July 2018

1 reference

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Anti-desmoglein 3 (Dsg3) monoclonal antibodies deplete desmosomes of Dsg3 and differ in their Dsg3-depleting activities related to pathogenicity

5 July 2018

1 reference

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5 July 2018

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p38MAPK inhibition prevents disease in pemphigus vulgaris mice

5 July 2018

1 reference

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Plakophilins: Multifunctional proteins or just regulators of desmosomal adhesion?

5 July 2018

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Desmoglein endocytosis and desmosome disassembly are coordinated responses to pemphigus autoantibodies

5 July 2018

1 reference

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Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display

5 July 2018

1 reference

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Regulation of desmosome assembly and adhesion

5 July 2018

1 reference

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IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model

5 July 2018

1 reference

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Working out the strength and flexibility of desmosomes

5 July 2018

1 reference

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Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability

5 July 2018

1 reference

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Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength

5 July 2018

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5 July 2018

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Desmoplakin is essential in epidermal sheet formation

5 July 2018

1 reference

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Central role of the plakoglobin-binding domain for desmoglein 3 incorporation into desmosomes

5 July 2018

1 reference

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A central role for the armadillo protein plakoglobin in the autoimmune disease pemphigus vulgaris

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Plakophilin 1 interferes with plakoglobin binding to desmoplakin, yet together with plakoglobin promotes clustering of desmosomal plaque complexes at cell-cell borders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Assembly pathway of desmoglein 3 to desmosomes and its perturbation by pemphigus vulgaris-IgG in cultured keratinocytes, as revealed by time-lapsed labeling immunoelectron microscopy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Extracellular domain of pemphigus vulgaris antigen (desmoglein 3) mediates weak homophilic adhesion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Identification of the plakoglobin-binding domain in desmoglein and its role in plaque assembly and intermediate filament anchorage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Isolation and symmetrical splitting of desmosomal structures in 9 M urea.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Biochemical characterization of desmosomal proteins isolated from bovine muzzle epidermis: amino acid and carbohydrate composition.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

CD63 antigen. A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Perp is a p63-regulated gene essential for epithelial integrity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

The armadillo family of structural proteins.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904546

Use of domain-swapped molecules for conformational epitope mapping of desmoglein 3 in pemphigus vulgaris

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19158843

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19158843

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In vitro keratinocyte dissociation assay for evaluation of the pathogenicity of anti-desmoglein 3 IgG autoantibodies in pemphigus vulgaris

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19158843

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/JID.2008.419

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference