Serotonin 2c receptor RNA editing in major depression and suicide (Q33997373)

30 July 2017

title

Serotonin 2c receptor RNA editing in major depression and suicide (English)

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30 July 2017

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4

Larry J Siever

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30 July 2017

Rebecca Lyddon

1

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30 July 2017

Andrew J Dwork

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2

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30 July 2017

Mehdi Keddache

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3

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30 July 2017

Stella Dracheva

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5

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30 July 2017

publication date

9 March 2012

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World Journal of Biological Psychiatry

30 July 2017

published in

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30 July 2017

volume

14

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30 July 2017

issue

8

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30 July 2017

page(s)

590-601

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Functions and regulation of RNA editing by ADAR deaminases

30 July 2017

cites work

1 reference

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Assessing serotonin receptor mRNA editing frequency by a novel ultra high-throughput sequencing method.

28 July 2018

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High-throughput multiplexed transcript analysis yields enhanced resolution of 5-hydroxytryptamine 2C receptor mRNA editing profiles.

28 July 2018

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28 July 2018

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Antidepressants increase neural progenitor cells in the human hippocampus

28 July 2018

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Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait.

28 July 2018

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28 July 2018

1 reference

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RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function

28 July 2018

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Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction

28 July 2018

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Serotonin-dopamine interaction as a focus of novel antidepressant drugs

28 July 2018

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Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies

28 July 2018

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ADAR gene family and A-to-I RNA editing: diverse roles in posttranscriptional gene regulation

28 July 2018

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ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy

28 July 2018

1 reference

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Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

The 5-HT2C receptor as a target for mood disorders

28 July 2018

1 reference

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Liver Disintegration in the Mouse Embryo Caused by Deficiency in the RNA-editing Enzyme ADAR1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Discriminative stimulus effects of m-chlorophenylpiperazine as a model of the role of serotonin receptors in anxiety

28 July 2018

1 reference

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Psychological autopsy studies of suicide: a systematic review

28 July 2018

1 reference

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RNA editing by adenosine deaminases that act on RNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Biochemical evidence that the atypical antipsychotic drugs clozapine and risperidone block 5-HT(2C) receptors in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Functions and mechanisms of RNA editing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2

28 July 2018

1 reference

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Altered G protein-coupling functions of RNA editing isoform and splicing variant serotonin2C receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Messenger RNA editing of the human serotonin 5-HT2C receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Regulation of serotonin-2C receptor G-protein coupling by RNA editing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Relapse of depression after rapid depletion of tryptophan

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Approaching the molecular pathology of suicide

28 July 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

A-to-I pre-mRNA editing of the serotonin 2C receptor: comparisons among inbred mouse strains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Recognition and coupling of A-to-I edited sites are determined by the tertiary structure of the RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Small sample inference for fixed effects from restricted maximum likelihood.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Candidate endophenotypes for genetic studies of suicidal behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Association between a serotonin transporter promoter region polymorphism and mood response during tryptophan depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Cyclic AMP response element-binding protein in post-mortem brain of teenage suicide victims: specific decrease in the prefrontal cortex but not the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Characterisation of agonist binding on human 5-HT2C receptor isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Serotonin 2C Receptor (5-HT2CR) mRNA Editing–Induced Down-Regulation of 5-HT2CR Function in Xenopus Oocytes: the Significance of Site C Editing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.630406

Increased cortical expression of an RNA editing enzyme occurs in major depressive suicide victims.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120662

Neurobiology of suicidal behaviour

29 October 2018

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12 December 2020

Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide

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12 December 2020

Evidence for accelerated desensitisation of 5-HT(2C) receptors following combined treatment with fluoxetine and the 5-HT(1A) receptor antagonist, WAY 100,635, in the rat

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12 December 2020

The stanley foundation brain collection and neuropathology consortium

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12 December 2020

Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication

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12 December 2020

10.3109/15622975.2011.630406

Identifiers

DOI

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30 July 2017

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30 July 2017

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