The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells (Q34002457)

30 July 2017

title

The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells (English)

1 reference

30 July 2017

Romain Roncagalli

2

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Grégory Verdeil

Grégory Verdeil

11

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Nathalie Auphan-Anezin

Nathalie Auphan-Anezin

Anne-Marie Schmitt-Verhulst

9

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Anne-Marie Schmitt-Verhulst

10

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Rudi Beyaert

Rudi Beyaert

7

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Geert van Loo

8

Geert van Loo

1 reference

30 July 2017

Marilyn Giordano

1

1 reference

30 July 2017

Pierre Bourdely

3

1 reference

30 July 2017

Lionel Chasson

4

1 reference

30 July 2017

Michel Buferne

5

1 reference

30 July 2017

Sho Yamasaki

6

1 reference

30 July 2017

language of work or name

English

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publication date

14 July 2014

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30 July 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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30 July 2017

volume

111

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30 July 2017

issue

30

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30 July 2017

page(s)

11115-11120

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Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

A20 in inflammation and autoimmunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

A new look at T cell receptor signaling to nuclear factor-κB

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Epithelial-mesenchymal-transition-like and TGFβ pathways associated with autochthonous inflammatory melanoma development in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

A20 controls macrophage to elicit potent cytotoxic CD4(+) T cell response.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

A20: linking a complex regulator of ubiquitylation to immunity and human disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Crosstalk in NF-κB signaling pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

STAT5-mediated signals sustain a TCR-initiated gene expression program toward differentiation of CD8 T cell effectors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Peripheral tolerance of CD8 T lymphocytes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

A critical requirement of interferon gamma-mediated angiostasis for tumor rejection by CD8+ T cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4121810

The blockade of immune checkpoints in cancer immunotherapy

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells, and systemic autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

IL-17 and TNF-α sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

Tumor-initiated inflammation overrides protective adaptive immunity in an induced melanoma model in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

c-Rel phenocopies PKCtheta but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406259111

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

21 January 2018

1 reference

12 December 2020

An Inducible Mouse Model of Melanoma Expressing a Defined Tumor Antigen

1 reference

12 December 2020

MALT1 directs B cell receptor–induced canonical nuclear factor-κB signaling selectively to the c-Rel subunit

1 reference

12 December 2020

CD8 T Cell Help for Innate Antitumor Immunity

1 reference

12 December 2020

A20 deficiency in B cells enhances B-cell proliferation and results in the development of autoantibodies

1 reference

12 December 2020

Activated STAT5 promotes long-lived cytotoxic CD8+ T cells that induce regression of autochthonous melanoma

1 reference

12 December 2020

Immunosuppression in inflammatory melanoma: can it be resisted by adoptively transferred T cells?

1 reference

12 December 2020

c-Rel is required for chromatin remodeling across the IL-2 gene promoter

1 reference

12 December 2020

Tumor-infiltrating lymphocytes exhibiting high ex vivo cytolytic activity fail to prevent murine melanoma tumor growth in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1406259111

1 reference

30 July 2017

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1 reference

30 July 2017

1 reference