Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome (Q34006076)

30 July 2017

title

Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome (English)

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30 July 2017

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Michael V Morabito

1

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30 July 2017

Atheir I Abbas

2

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30 July 2017

Jennifer L Hood

3

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30 July 2017

Robert A Kesterson

4

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30 July 2017

Michelle M Jacobs

5

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30 July 2017

David S Kump

6

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30 July 2017

David L Hachey

7

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30 July 2017

Bryan L Roth

8

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30 July 2017

Ronald B Emeson

9

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30 July 2017

publication date

13 April 2010

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30 July 2017

published in

Neurobiology of Disease

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30 July 2017

volume

39

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30 July 2017

issue

2

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30 July 2017

page(s)

169-180

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describes a project that uses

30 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2906772/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Impact of RNA editing on functions of the serotonin 2C receptor in vivo

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A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism

5 July 2018

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Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait.

5 July 2018

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Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour

5 July 2018

1 reference

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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis

5 July 2018

1 reference

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Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass

5 July 2018

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Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

5 July 2018

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SnoRNA Snord116 (Pwcr1/MBII-85) deletion causes growth deficiency and hyperphagia in mice

5 July 2018

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Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation

5 July 2018

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The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C

5 July 2018

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5 July 2018

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Lack of Pwcr1/MBII-85 snoRNA is critical for neonatal lethality in Prader-Willi syndrome mouse models

5 July 2018

1 reference

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ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs

5 July 2018

1 reference

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Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome

5 July 2018

1 reference

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Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene

5 July 2018

1 reference

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The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis

5 July 2018

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Prader-Willi syndrome: advances in genetics, pathophysiology and treatment

5 July 2018

1 reference

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RNA Editing Induces Variation in Desensitization and Trafficking of 5-Hydroxytryptamine 2c Receptor Isoforms

5 July 2018

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Nervous system targets of RNA editing identified by comparative genomics

5 July 2018

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RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders

5 July 2018

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Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Evidence for the role of PWCR1/HBII-85 C/D box small nucleolar RNAs in Prader-Willi syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Stable isotope ratios using cavity ring-down spectroscopy: determination of 13C/12C for carbon dioxide in human breath

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

5 July 2018

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Genome organization, function, and imprinting in Prader-Willi and Angelman syndromes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria

5 July 2018

1 reference

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RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein

5 July 2018

1 reference

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RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization

5 July 2018

1 reference

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Functions and mechanisms of RNA editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Altered G protein-coupling functions of RNA editing isoform and splicing variant serotonin2C receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Disruption of the mouse necdin gene results in early post-natal lethality

5 July 2018

1 reference

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Fasting regulates hypothalamic neuropeptide Y, agouti-related peptide, and proopiomelanocortin in diabetic mice independent of changes in leptin or insulin

5 July 2018

1 reference

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Messenger RNA editing of the human serotonin 5-HT2C receptor

5 July 2018

1 reference

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A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes

5 July 2018

1 reference

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Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Rodent mutant models of obesity and their correlations to human obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

A mouse model for Prader-Willi syndrome imprinting-centre mutations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Regulation of serotonin-2C receptor G-protein coupling by RNA editing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Identification, molecular cloning, and distribution of a short variant of the 5-hydroxytryptamine2C receptor produced by alternative splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Isotope dilution measurement of breast-milk production in Chilean urban mothers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Alternative production of calcitonin and CGRP mRNA is regulated at the calcitonin-specific splice acceptor

5 July 2018

1 reference

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

5 July 2018

1 reference

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The distribution and cellular localization of the serotonin 1C receptor mRNA in the rodent brain examined by in situ hybridization histochemistry. Comparison with receptor binding distribution.

5 July 2018

1 reference

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Inactivation of the mouse Magel2 gene results in growth abnormalities similar to Prader-Willi syndrome

5 July 2018

1 reference

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5-HT(2C) receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice.

29 October 2018

1 reference

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A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts.

29 October 2018

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How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing.

29 October 2018

1 reference

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Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT(2C) receptor mutant mice

29 October 2018

1 reference

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Activation of central melanocortin pathways by fenfluramine

29 October 2018

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Effects of energy expenditure and Ucp1 on photoperiod-induced weight gain in collard lemmings

29 October 2018

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Small nucleolar RNAs: an abundant group of noncoding RNAs with diverse cellular functions

29 October 2018

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Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.

29 October 2018

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Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome.

29 October 2018

1 reference

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Necdin-deficient mice do not show lethality or the obesity and infertility of Prader-Willi syndrome

29 October 2018

1 reference

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Imprinting of a RING zinc-finger encoding gene in the mouse chromosome region homologous to the Prader-Willi syndrome genetic region

29 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2906772

Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene

29 October 2018

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29 October 2018

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29 October 2018

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Human-milk intake measured by administration of deuterium oxide to the mother: a comparison with the test-weighing technique

29 October 2018

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Theory of use of the turnover rates of body water for measuring energy and material balance

29 October 2018

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12 December 2020

Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2

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Applicability of the D2018 method to the measurement of the total carbon dioxide output of obese mice

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Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide

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A method for the routine assessment of fore- and hindlimb grip strength of rats and mice

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Evidence for genetic modifiers of postnatal lethality in PWS-IC deletion mice

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A candidate mouse model for Prader-Willi syndrome which shows an absence of Snrpn expression

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Measurement of total energy and material balance in rats by means of doubly labeled water

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10.1016/J.NBD.2010.04.004

Identifiers

DOI

1 reference

30 July 2017

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30 July 2017

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