Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells (Q34007569)

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English	Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

0 references

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

breast neoplasm

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based on heuristic

inferred from title

author name string

Yu-Dong Zhou

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Yong-Pil Kim

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Kaleem Asjad Mohammed

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Deborah K Jones

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Ilias Muhammad

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

D Chuck Dunbar

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Dale G Nagle

7

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

1 June 2005

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Europe PubMed Central

PubMed publication ID

30 July 2017

Journal of Natural Products

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Europe PubMed Central

PubMed publication ID

30 July 2017

68

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Europe PubMed Central

PubMed publication ID

30 July 2017

6

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Europe PubMed Central

PubMed publication ID

30 July 2017

947-950

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Europe PubMed Central

PubMed publication ID

30 July 2017

Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Exploiting tumour hypoxia in cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

HIF-1 as a target for drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Targeting HIF-1 for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

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The biology of VEGF and its receptors

1 reference

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5 July 2018

The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Effects of emetine and cycloheximide on mitochondrial protein synthesis in different systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

The prevention by inhibitors of brain proptein synthesis of the hyperactivity and hyperpyrexia produced in rats by monoamine oxidase inhibition and the administration of L-tryptophan or 5-methoxy-N,N-dimethyltryptamine

1 reference

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5 July 2018

Toxicity determined in vitro by morphological alterations and neutral red absorption

1 reference

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5 July 2018

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Chemotherapy of Human Intestinal Parasitic Diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

5 July 2018

Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

29 October 2018

Antiparasitic alkaloids from Psychotria klugii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

29 October 2018

Suppression of tumor growth through disruption of hypoxia-inducible transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2907142

29 October 2018

Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: evidence for cytotoxic mechanisms different from inhibition of protein synthesis.

1 reference

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29 October 2018

Mechanisms of cell death in hypoxia/reoxygenation injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15974627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of protein biosynthesis. V. Effects of emetine on protein and nucleic acid biosynthesis in HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15974627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophosphamide plus emetine in lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15974627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of emetine (NSC-33669) in the treatment of solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15974627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/NP050029M

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

0 references

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