NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs. (Q34009346)

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English	NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.	scientific article

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12 February 2020

NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs (English)

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12 February 2020

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histone acetylation

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based on heuristic

inferred from title

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12 February 2020

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Sangwoon Chung

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12 February 2020

Isaac K Sundar

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12 February 2020

Jae-Woong Hwang

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12 February 2020

Timothy S Blackwell

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12 February 2020

Vuokko L Kinnula

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12 February 2020

Michael Bulger

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12 February 2020

Hongwei Yao

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12 February 2020

Irfan Rahman

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24 August 2011

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12 February 2020

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12 February 2020

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12 February 2020

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12 February 2020

e23488

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12 February 2020

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24 August 2011

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Chronic obstructive pulmonary disease and lung cancer: new molecular insights

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Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease

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5 July 2018

TNFα induced noncanonical NF-κB activation is attenuated by RIP1 through stabilization of TRAF2.

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5 July 2018

Non-canonical NF-κB signaling pathway

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NF-κB inducing kinase: A key regulator in the immune system and in cancer

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5 July 2018

Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylation

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5 July 2018

Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of I{kappa}B kinases in mice: impact on histone acetylation

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Epigenomic alterations and gene expression profiles in respiratory epithelia exposed to cigarette smoke condensate.

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5 July 2018

SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress

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Allosteric regulation of the ubiquitin:NIK and ubiquitin:TRAF3 E3 ligases by the lymphotoxin-beta receptor

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5 July 2018

IKKalpha and IKKbeta each function to regulate NF-kappaB activation in the TNF-induced/canonical pathway

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5 July 2018

Oxidative stress increases phosphorylation of IkappaB kinase-alpha by enhancing NF-kappaB-inducing kinase after transient focal cerebral ischemia

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5 July 2018

Anti-inflammatory effect of a selective IkappaB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke.

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5 July 2018

Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications

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Current concepts on the role of inflammation in COPD and lung cancer

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5 July 2018

Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen

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Epigenetics and dermatological disease

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5 July 2018

New regulators of NF-kappaB in inflammation

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Promotion of lung carcinogenesis by chronic obstructive pulmonary disease-like airway inflammation in a K-ras-induced mouse model

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In utero supplementation with methyl donors enhances allergic airway disease in mice

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5 July 2018

RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke

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5 July 2018

Combinatorial patterns of histone acetylations and methylations in the human genome

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Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction.

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5 July 2018

Control of canonical NF-kappaB activation through the NIK-IKK complex pathway

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5 July 2018

IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung

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5 July 2018

Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD.

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5 July 2018

SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.

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5 July 2018

NF-kappaB-inducing kinase regulates cyclooxygenase 2 gene expression in macrophages by phosphorylation of PU.1.

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5 July 2018

Epigenetic regulation of airway inflammation.

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5 July 2018

Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB

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5 July 2018

COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1.

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5 July 2018

Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells

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5 July 2018

Regulation and function of IKK and IKK-related kinases

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5 July 2018

NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha

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Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase

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5 July 2018

Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-kappaB inducing kinase NIK.

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Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

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5 July 2018

Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles

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NF-kappa B p65 transactivation domain is involved in the NF-kappa B-inducing kinase pathway

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Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus.

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Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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5 July 2018

Histone acetylation in chromatin structure and transcription

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21 January 2018

The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.

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21 January 2018

Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice.

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21 January 2018

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21 January 2018

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IkappaB kinase alpha and p65/RelA contribute to optimal epidermal growth factor-induced c-fos gene expression independent of IkappaBalpha degradation

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21 January 2018

Controlling the fate of NIK: a central stage in noncanonical NF-kappaB signaling

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Oxidative stress and cigarette smoke alter chromatin remodeling but differentially regulate NF-kappaB activation and proinflammatory cytokine release in alveolar epithelial cells

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12 February 2020

2011PLoSO...623488C

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12 February 2020

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