Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation (Q34014502)

30 July 2017

title

Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation (English)

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30 July 2017

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April L Colosimo

4

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author name string

Koren K Mann

1

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30 July 2017

Alessandra M S Padovani

2

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30 July 2017

Qi Guo

3

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30 July 2017

Ho-Young Lee

5

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30 July 2017

Jonathan M Kurie

6

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30 July 2017

Wilson H Miller

7

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30 July 2017

language of work or name

English

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publication date

22 September 2005

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Journal of Clinical Investigation

30 July 2017

published in

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30 July 2017

volume

115

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30 July 2017

issue

10

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30 July 2017

page(s)

2924-2933

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Retinoic acid and arsenic trioxide cooperate for apoptosis through phosphorylated RXR alpha.

30 July 2017

cites work

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All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia

5 July 2018

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5 July 2018

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JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells

5 July 2018

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5 July 2018

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5 July 2018

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Arsenic trioxide is a potent inhibitor of the interaction of SMRT corepressor with Its transcription factor partners, including the PML-retinoic acid receptor alpha oncoprotein found in human acute promyelocytic leukemia

5 July 2018

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5 July 2018

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Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Arsenic trioxide as an inducer of apoptosis and loss of PML/RAR alpha protein in acute promyelocytic leukemia cells

5 July 2018

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Phosphorylation of activation functions AF-1 and AF-2 of RAR alpha and RAR gamma is indispensable for differentiation of F9 cells upon retinoic acid and cAMP treatment

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

5 July 2018

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Different ways to regulate the PPARalpha stability.

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Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide

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Combined effect of all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia cells in vitro and in vivo

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Identifiers

DOI

10.1172/JCI23628

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30 July 2017

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30 July 2017

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