Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology (Q34016431)

30 July 2017

title

Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology (English)

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30 July 2017

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lymphoblastic leukemia

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11

Tariq Enver

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13

Adele K Fielding

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Bella Patel

1

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30 July 2017

Aditi Dey

2

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30 July 2017

Anna Z Castleton

3

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30 July 2017

Claire Schwab

4

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30 July 2017

Edward Samuel

5

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30 July 2017

Janani Sivakumaran

6

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30 July 2017

Brendan Beaton

7

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Nahid Zareian

8

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Christie Yu Zhang

9

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Lena Rai

10

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Anthony V Moorman

12

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language of work or name

English

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publication date

13 May 2014

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30 July 2017

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30 July 2017

volume

124

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issue

1

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30 July 2017

page(s)

96-105

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The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial

30 July 2017

cites work

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Successful engraftment of human acute lymphoblastic leukemia cells in NOD/SCID mice via intrasplenic inoculation

5 July 2018

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Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

5 July 2018

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Modern therapy of acute lymphoblastic leukemia

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Effects of sublethal irradiation on patterns of engraftment after murine bone marrow transplantation

5 July 2018

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Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993.

5 July 2018

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5 July 2018

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

5 July 2018

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Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

5 July 2018

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Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.

5 July 2018

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In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties

5 July 2018

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Creation of "humanized" mice to study human immunity

5 July 2018

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Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95.

5 July 2018

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

5 July 2018

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Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial

5 July 2018

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In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment

5 July 2018

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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

5 July 2018

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Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling

5 July 2018

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Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.

5 July 2018

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The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow.

5 July 2018

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia

29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolid

29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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29 October 2018

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Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia

29 October 2018

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Growth and biologic properties of karyotypically defined subcategories of adult acute lymphocytic leukemia in mice with severe combined immunodeficiency

29 October 2018

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12 December 2020

Survival of human leukaemic B-cell precursors is supported by stromal cells and cytokines: association with the expression of bcl-2 protein

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12 December 2020

Relapse in children with acute lymphoblastic leukemia involving selection of a preexisting drug-resistant subclone

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12 December 2020

Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

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12 December 2020

Comparison of childhood leukemia initiating cell populations in NOD/SCID and NSG mice

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12 December 2020

In vitro drug resistance profiles of adult versus childhood acute lymphoblastic leukaemia

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12 December 2020

Minimal residual disease tests provide an independent predictor of clinical outcome in adult acute lymphoblastic leukemia

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12 December 2020

Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro

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12 December 2020

Successful engraftment by leukemia initiating cells in adult acute lymphoblastic leukemia after direct intrahepatic injection into unconditioned newborn NOD/SCID mice

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12 December 2020

Antigen receptor gene rearrangements reflect on the heterogeneity of adult Acute Lymphoblastic Leukaemia (ALL) with implications of cell-origin of ALL subgroups - a UKALLXII study

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12 December 2020

Good engraftment of B-cell precursor ALL in NOD-SCID mice

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10.1182/BLOOD-2014-01-549352

Identifiers

DOI

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30 July 2017

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30 July 2017

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