Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine. (Q34020879)

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English	Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine.	scientific article

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scholarly article

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19 January 2020

Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine (English)

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19 January 2020

nitrososulfamethoxazole

1 reference

ChEBI release 2020-05-28

sulfamethoxazole hydroxylamine

1 reference

ChEBI release 2020-05-28

6

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19 January 2020

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Sachin Bhusari

1

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19 January 2020

Mahmoud Abouraya

2

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19 January 2020

Marcia L Padilla

3

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19 January 2020

Marie E Pinkerton

4

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19 January 2020

Nicholas J Drescher

5

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19 January 2020

Lauren A Trepanier

7

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19 January 2020

publication date

11 March 2010

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19 January 2020

Archives of Toxicology

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19 January 2020

84

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19 January 2020

8

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19 January 2020

597-607

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19 January 2020

"Danger" conditions increase sulfamethoxazole-protein adduct formation in human antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Cotrimoxazole prophylaxis for opportunistic infections in adults with HIV

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Plasma cysteine deficiency and decreased reduction of nitrososulfamethoxazole with HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

The enzymes of glutathione synthesis: gamma-glutamylcysteine synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Oxidative stress and thiol depletion in plasma and peripheral blood lymphocytes from HIV-infected patients: toxicological and pathological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Adverse reactions to trimethoprim-sulfamethoxazole in hospitalized patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Adverse Reactions to Trimethoprim-Sulfamethoxazole in Patients with the Acquired Immunodeficiency Syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Comparative studies on the influence of L-ascorbate, D-arabino-ascorbate and 5-oxo-D-gluconate on the amounts of cytochromes P-450 and b5 in liver microsomes of guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Influence of L-ascorbate on the contents of cytochromes P-450 and b5 in several organs of guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Adverse reactions to sulfisoxazole, sulfamethoxazole, and nitrofurantoin. Manifestations and specific reaction rates during 2,118 courses of therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Glutathione deficiency decreases tissue ascorbate levels in newborn rats: ascorbate spares glutathione and protects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

Hepatic microsomal metabolism of sulfamethoxazole to the hydroxylamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

28 July 2018

A randomized trial of N-acetylcysteine for prevention of trimethoprim-sulfamethoxazole hypersensitivity reactions in Pneumocystis carinii pneumonia prophylaxis (CTN 057). Canadian HIV Trials Network 057 Study Group

1 reference

https://api.crossref.org/works/10.1007%2FS00204-010-0530-Z

21 January 2018

Covalent binding of the nitroso metabolite of sulfamethoxazole is important in induction of drug-specific T-cell responses in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

NADH cytochrome b5 reductase and cytochrome b5 catalyze the microsomal reduction of xenobiotic hydroxylamines and amidoximes in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Haptenation of sulfonamide reactive metabolites to cellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Prophylaxis for human immunodeficiency virus-related Pneumocystis carinii pneumonia: using simulation modeling to inform clinical guidelines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Efficacy of trimethoprim-sulfamethoxazole for the prevention of bacterial infections in a randomized prophylaxis trial of patients with advanced HIV infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Erythrocytic glutathione and plasma cysteine status of human immunodeficient patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Status of selected nutrients and progression of human immunodeficiency virus type 1 infection

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29 October 2018

A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions.

1 reference

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29 October 2018

Discontinuation of Primary Prophylaxis againstPneumocystis cariniiPneumonia in HIV-1–Infected Adults Treated with Combination Antiretroviral Therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910208

29 October 2018

Association of drug-serum protein adducts and anti-drug antibodies in dogs with sulphonamide hypersensitivity: a naturally occurring model of idiosyncratic drug toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221587

12 December 2020

based on heuristic

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Adverse reactions to cotrimoxazole in HIV-infected patients: predictive factors and subsequent HIV disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depletion of glutathione in vivo as a method of improving the therapeutic ratio of misonidazole and SR 2508

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylation phenotype and cutaneous hypersensitivity to trimethoprim-sulphamethoxazole in HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythrocyte glutathione deficiency in symptom-free HIV infection is associated with decreased synthesis rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20221587

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1007/S00204-010-0530-Z

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19 January 2020

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19 January 2020

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19 January 2020

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