Nucleic acid vaccines: research tool or commercial reality (Q34023547)

30 July 2017

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title

Nucleic acid vaccines: research tool or commercial reality (English)

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30 July 2017

1

Babiuk LA

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30 July 2017

Babiuk SL

2

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30 July 2017

Loehr BI

series ordinal

3

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30 July 2017

van Drunnen Littel-van den Hur

series ordinal

4

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30 July 2017

publication date

1 August 2000

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Veterinary Immunology and Immunopathology

30 July 2017

published in

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30 July 2017

volume

76

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30 July 2017

issue

1-2

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30 July 2017

page(s)

1-23

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PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization

30 July 2017

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7 January 2021

Alphaviruses as vectors for gene delivery

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7 January 2021

Genetic fusion of chemokines to a self tumor antigen induces protective, T-cell dependent antitumor immunity

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7 January 2021

A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA.

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7 January 2021

Particle-mediated DNA immunization of cattle confers long-lasting immunity against bovine herpesvirus-1

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7 January 2021

A strategy to improve the efficacy of vaccination against tuberculosis and leprosy

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7 January 2021

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

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7 January 2021

Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients

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7 January 2021

Ability of insulin and DsRNA to induce interferon system and Hsp 70 in fibroblast and epithelial cells in relation to their effects on cell growth

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7 January 2021

DNA-based immunization by in vivo transfection of dendritic cells

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7 January 2021

Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10.

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7 January 2021

Gene vaccination with naked plasmid DNA: mechanism of CTL priming

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7 January 2021

Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA.

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7 January 2021

DNA vaccination using expression vectors carrying FIV structural genes induces immune response against feline immunodeficiency virus

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7 January 2021

High expression of naked plasmid DNA in muscles of young rodents.

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7 January 2021

Oral somatic transgene vaccination using attenuated S. typhimurium.

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7 January 2021

Bm86 antigen induces a protective immune response against Boophilus microplus following DNA and protein vaccination in sheep

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7 January 2021

Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells

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7 January 2021

Induction of protective immunity to Theileria annulata using two major merozoite surface antigens presented by different delivery systems.

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7 January 2021

Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer.

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7 January 2021

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

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7 January 2021

Factors influencing cellular immune responses to feline immunodeficiency virus induced by DNA vaccination

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Priming of cytotoxic T lymphocytes by DNA vaccines: requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes.

1 reference

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7 January 2021

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

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7 January 2021

Immunogenicity of vector DNA vaccine constructs of pseudorabies virus immediate early gene (IE180) in mice and swine

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7 January 2021

Differential cellular and humoral immune responses to HCV core and HBV envelope proteins after genetic immunizations using chimeric constructs

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7 January 2021

Potency of an experimental DNA vaccine against Aujeszky's disease in pigs

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7 January 2021

Protection of pigs against Aujeszky's disease by DNA vaccination

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization.

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7 January 2021

Vaccination of pigs against pseudorabies virus with plasmid DNA encoding glycoprotein D.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Intramuscular injection of plasmid DNA encoding cottontail rabbit papillomavirus E1, E2, E6 and E7 induces T cell-mediated but not humoral immune responses in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

DNA immunization against herpes simplex virus: enhanced efficacy using a Sindbis virus-based vector

1 reference

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7 January 2021

Vaccination of cattle with a DNA plasmid encoding the bovine viral diarrhoea virus major glycoprotein E2.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Can patents deter innovation? The anticommons in biomedical research

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7 January 2021

A plasmid-based self-amplifying Sindbis virus vector

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7 January 2021

Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells

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7 January 2021

Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human use.

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7 January 2021

Serum and colostrum antibody responses induced by jet-injection of sheep with DNA encoding a Cryptosporidium parvum antigen

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7 January 2021

Nucleic acid immunization protects dogs against challenge with virulent canine parvovirus

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7 January 2021

Genetic to genomic vaccination

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7 January 2021

Poly(DL-lactide-co-glycolide)-encapsulated plasmid DNA elicits systemic and mucosal antibody responses to encoded protein after oral administration.

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7 January 2021

DNA is as effective as protein at inducing antibody in fish

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7 January 2021

Mammalian granulocyte-macrophage colony-stimulating factor and some CpG motifs have an effect on the immunogenicity of DNA and subunit vaccines in fish

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7 January 2021

Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes

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7 January 2021

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

1 reference

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7 January 2021

Lymphocyte activation by CpG dinucleotide motifs in prokaryotic DNA.

1 reference

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7 January 2021

The role of CpG dinucleotides in DNA vaccines

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Antibody and cellular immune responses of swine following immunisation with plasmid DNA encoding the PRRS virus ORF's 4, 5, 6 and 7.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Study of the delivery of the gD gene of pseudorabies virus to one-day-old piglets by adenovirus or plasmid DNA as ways to by-pass the inhibition of immune response by colostral antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Altering the cellular location of an antigen expressed by a DNA-based vaccine modulates the immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Induction of immune responses to bovine herpesvirus type 1 gD in passively immune mice after immunization with a DNA-based vaccine

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Protection against respiratory syncytial virus infection by DNA immunization

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Immunostimulatory DNA: sequence-dependent production of potentially harmful or useful cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Immunization of the female genital tract with a DNA-based vaccine

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Antibody responses to DNA vaccination of horses using the influenza virus hemagglutinin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Immunization of pigs with a particle-mediated DNA vaccine to influenza A virus protects against challenge with homologous virus

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

DNA vaccination with cytokine fusion constructs biases the immune response to ovalbumin.

1 reference

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7 January 2021

Lipid fusion in oligonucleotide and gene delivery with cationic lipids

1 reference

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7 January 2021

Effective priming of neonates born to immune dams against the immunogenic pseudorabies virus glycoprotein gD by replication-incompetent adenovirus-mediated gene transfer at birth

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7 January 2021

Immunization of dogs and cats with a DNA vaccine against rabies virus

1 reference

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7 January 2021

Immunization of dogs with a DNA vaccine induces protection against rabies virus

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Immune response in pigs vaccinated with plasmid DNA encoding ORF5 of porcine reproductive and respiratory syndrome virus

1 reference

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7 January 2021

Manipulation of HIV-1 gp120-specific immune responses elicited via gene gun-based DNA immunization

1 reference

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7 January 2021

Developing recombinant and synthetic vaccines for the treatment of melanoma.

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7 January 2021

Enhancement of feline immunodeficiency virus (FIV) infection after DNA vaccination with the FIV envelope

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Sequential nucleic acid and recombinant adenovirus vaccination induces host-protective immune responses against Taenia ovis infection in sheep

1 reference

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7 January 2021

DNA-mediated immunization with glycoprotein D of equine herpesvirus 1 (EHV-1) in a murine model of EHV-1 respiratory infection

1 reference

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7 January 2021

Protection of chickens from Newcastle disease by vaccination with a linear plasmid DNA expressing the F protein of Newcastle disease virus

1 reference

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7 January 2021

Induction of systemic and mucosal immune responses to human immunodeficiency virus type 1 by a DNA vaccine formulated with QS-21 saponin adjuvant via intramuscular and intranasal routes

1 reference

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7 January 2021

Immunostimulatory DNA sequences necessary for effective intradermal gene immunization

1 reference

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7 January 2021

Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Immunization of cattle with a BHV1 vector vaccine or a DNA vaccine both coding for the G protein of BRSV

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Comparison of DNA application methods to reduce BRSV shedding in cattle

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7 January 2021

Enhanced protective response and immuno-adjuvant effects of porcine GM-CSF on DNA vaccination of pigs against Aujeszky's disease virus.

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7 January 2021

International meeting on the nucleic acid vaccines for the prevention of infectious disease and regulating nucleic acid (DNA) vaccines. Natcher Conference Center NIH, Bethesda, MD 5-8 February, 1996.

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7 January 2021

Intracutaneous vaccination of rabbits with the cottontail rabbit papillomavirus (CRPV) L1 gene protects against virus challenge .

1 reference

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7 January 2021

Genetic immunization is a simple method for eliciting an immune response

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https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

New directions in liposome gene delivery

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7 January 2021

Alphavirus expression vectors and their use as recombinant vaccines: a minireview.

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7 January 2021

Heterologous protection against influenza by injection of DNA encoding a viral protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Intradermal immunization with a bovine herpesvirus-1 DNA vaccine induces protective immunity in cattle

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Immunization of neonates with DNA encoding a bovine herpesvirus glycoprotein is effective in the presence of maternal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Advances in the development and evaluation of bovine herpesvirus 1 vaccines

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7 January 2021

Effect of vaccination route and composition of DNA vaccine on the induction of protective immunity against pseudorabies infection in pigs

1 reference

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7 January 2021

Protection of turkeys against Chlamydia psittaci challenge by gene gun-based DNA immunizations.

1 reference

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7 January 2021

Turkeys are protected from infection with Chlamydia psittaci by plasmid DNA vaccination against the major outer membrane protein

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7 January 2021

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine

1 reference

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7 January 2021

Plasmid DNA encoding replicating foot-and-mouth disease virus genomes induces antiviral immune responses in swine.

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7 January 2021

Analysis of reporter gene expression in ovine dermis and afferent lymph dendritic cells in vitro and in vivo

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7 January 2021

Reduction of antigen expression from DNA vaccines by coadministered oligodeoxynucleotides

1 reference

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7 January 2021

Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

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7 January 2021

Polyvalent vaccination against hepatitis B surface and core antigen using a dicistronic expression plasmid.

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https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Direct gene transfer into mouse muscle in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

The adjuvant effects of mycoviral dsRNA and polyinosinic:polycytidylic acid on the murine immune response

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7 January 2021

Gene transfer facilitated by a cellular targeting molecule, reovirus protein sigma1.

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7 January 2021

Depth-targeted efficient gene delivery and expression in the skin by pulsed electric fields: an approach to gene therapy of skin aging and other diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

Self-replicating Semliki Forest virus RNA as recombinant vaccine

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https://api.crossref.org/works/10.1016%2FS0165-2427%2800%2900198-7

7 January 2021

10.1016/S0165-2427(00)00198-7

Identifiers

DOI

1 reference

30 July 2017

1 reference