The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemical libraries (Q34024345)

30 July 2017

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title

The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemical libraries (English)

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30 July 2017

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Charles A Lessman

1

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30 July 2017

1 September 2011

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Birth Defects Research Part C: Embryo Today Reviews

30 July 2017

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30 July 2017

93

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30 July 2017

3

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30 July 2017

268-280

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Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism

30 July 2017

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Pentylenetetrazole induced changes in zebrafish behavior, neural activity and c-fos expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish offer the potential for a primary screen to identify a wide variety of potential anticonvulsants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Swimming into the future of drug discovery: in vivo chemical screens in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

A behavioral screen for isolating zebrafish mutants with visual system defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish: a complete animal model for in vivo drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Modeling cardiovascular disease in the zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Chemical screening for hair cell loss and protection in the zebrafish lateral line

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

A high-throughput chemically induced inflammation assay in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish as a model for vertebrate hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Anxiolytic effects of erythrinian alkaloids from Erythrina mulungu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

High-throughput behavioral screens: the first step towards finding genes involved in vertebrate brain function using zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Image-based fluidic sorting system for automated Zebrafish egg sorting into multiwell plates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Using zebrafish to assess the impact of drugs on neural development and function

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.20212

In vivo structure-activity relationship study of dorsomorphin analogues identifies selective VEGF and BMP inhibitors.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.20212

Large-scale small-molecule screen using zebrafish embryos

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.20212

Acute neuroactive drug exposures alter locomotor activity in larval zebrafish.

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.20212

A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Chemical genetic screening in the zebrafish embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Drug screening in a zebrafish model of Duchenne muscular dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

21 January 2018

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https://api.crossref.org/works/10.1002%2FBDRC.20212

Hemostasis in Danio rerio: is the zebrafish a useful model for platelet research?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

In vivo imaging of embryonic vascular development using transgenic zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Oocyte maturation: converting the zebrafish oocyte to the fertilizable egg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Computer-aided meiotic maturation assay (CAMMA) of zebrafish (danio rerio) oocytes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Use of flatbed transparency scanners in zebrafish research: versatile and economical adjuncts to traditional imaging tools for the Danio rerio laboratory

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Acute effects of alcohol on larval zebrafish: a genetic system for large-scale screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Technology for high-throughput screens: the present and future using zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Significance of the zebrafish model in the discovery of bioactive molecules from nature

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Generation of FGF reporter transgenic zebrafish and their utility in chemical screens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

A chemical genetic screen for cell cycle inhibitors in zebrafish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Small molecule screening in the zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Forward genetic analysis of visual behavior in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

A chemical screen to identify novel inhibitors of fin regeneration in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

High-throughput in vivo vertebrate screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Novel chemical suppressors of long QT syndrome identified by an in vivo functional screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

A novel high-throughput imaging system for automated analyses of avoidance behavior in zebrafish larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish as a model organism to evaluate drugs potentially able to modulate sirtuin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

SCORE imaging: specimen in a corrected optical rotational enclosure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Leukemic cell xenograft in zebrafish embryo for investigating drug efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish: an integrative system for neurogenomics and neurosciences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Molecular cloning and expression analysis of P-selectin from Zebrafish (Danio rerio).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Automated image-based phenotypic analysis in zebrafish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Simple vertebrate models for chemical genetics and drug discovery screens: lessons from zebrafish and Xenopus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Multi-step usage of in vivo models during rational drug design and discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

Zebrafish embryos as models for embryotoxic and teratological effects of chemicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBDRC.20212

21 January 2018

Identifiers

DOI

10.1002/BDRC.20212

1 reference

30 July 2017

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PubMed ID

21932435