A synthetic homing endonuclease-based gene drive system in the human malaria mosquito (Q34026609)

30 July 2017

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito (English)

1 reference

30 July 2017

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Nikolai Windbichler

1

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Blake T. Hovde

Blake T Hovde

7

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David Baker

David Baker

8

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Hui Li

Hui Li

5

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Umut Y Ulge

Umut Y Ulge

Philippos Aris Papathanos

6

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Philippos Aris Papathanos

3

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Andrea Crisanti

11

Andrea Crisanti

1 reference

30 July 2017

10

Austin Burt

1 reference

30 July 2017

2

Miriam Menichelli

1 reference

30 July 2017

Summer B Thyme

4

1 reference

30 July 2017

Raymond J Monnat

9

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30 July 2017

language of work or name

English

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publication date

20 April 2011

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30 July 2017

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30 July 2017

473

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30 July 2017

212-215

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30 July 2017

7346

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https://scigraph.springernature.com/pub.10.1038/nature09937

30 July 2017

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cites work

Site-specific integration and expression of an anti-malarial gene in transgenic Anopheles gambiae significantly reduces Plasmodium infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Activation of Akt signaling reduces the prevalence and intensity of malaria parasite infection and lifespan in Anopheles stephensi mosquitoes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Exploitation of binding energy for catalysis and design

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Heritable targeted mutagenesis in maize using a designed endonuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Engineered I-CreI derivatives cleaving sequences from the human XPC gene can induce highly efficient gene correction in mammalian cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Homing endonuclease I-CreI derivatives with novel DNA target specificities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Computational redesign of endonuclease DNA binding and cleavage specificity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Gene drive systems for insect disease vectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Homing endonuclease structure and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

An anti-Chitinase malaria transmission-blocking single-chain antibody as an effector molecule for creating a Plasmodium falciparum-refractory mosquito

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Homing endonuclease genes: the rise and fall and rise again of a selfish element

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Transgenic anopheline mosquitoes impaired in transmission of a malaria parasite

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Extraordinary sex ratios. A sex-ratio theory for sex linkage and inbreeding has new implications in cytogenetics and entomology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093433

Possible use of translocations to fix desirable genes in insect pest populations.

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

21 January 2018

Extraordinary Sex Ratios

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Malaria control with genetically manipulated insect vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Bee venom phospholipase inhibits malaria parasite development in transgenic mosquitoes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Site-specific selfish genes as tools for the control and genetic engineering of natural populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

An Anopheles transgenic sexing strain for vector control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Outcrossed sex allows a selfish gene to invade yeast populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Direct regulation of rhodopsin 1 by Pax-6/eyeless in Drosophila: evidence for a conserved function in photoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

High efficiency germ-line transformation of mosquitoes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Impact of genetic manipulation on the fitness of Anopheles stephensi mosquitoes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Coevolution of a Homing Endonuclease and Its Host Target Sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Directed evolution and substrate specificity profile of homing endonuclease I-SceI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Macromolecular modeling with rosetta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Protein production by auto-induction in high density shaking cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE09937

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE09937

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference