Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity (Q34030886)

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English	Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity	scientific article

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity (English)

1 reference

Europe PubMed Central

30 July 2017

0 references

1 reference

based on heuristic

inferred from title

immunologic adjuvant

1 reference

based on heuristic

inferred from title

Philippa Marrack

object named as

Philippa Marrack

7

0 references

6

object named as

John W Kappler

1 reference

Europe PubMed Central

30 July 2017

1

object named as

Amy S McKee

1 reference

Europe PubMed Central

30 July 2017

3

object named as

Megan K L MacLeod

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Europe PubMed Central

30 July 2017

author name string

Michael W Munks

2

1 reference

Europe PubMed Central

30 July 2017

Courtney J Fleenor

4

1 reference

Europe PubMed Central

30 July 2017

Nico Van Rooijen

5

1 reference

Europe PubMed Central

30 July 2017

language of work or name

0 references

publication date

4 September 2009

1 reference

Europe PubMed Central

30 July 2017

Journal of Immunology

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Europe PubMed Central

30 July 2017

183

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Europe PubMed Central

30 July 2017

7

1 reference

Europe PubMed Central

30 July 2017

4403-4414

1 reference

Europe PubMed Central

30 July 2017

Basophils trump dendritic cells as APCs for T(H)2 responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Immunological and inflammatory functions of the interleukin-1 family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

CD4 memory T cells divide poorly in response to antigen because of their cytokine profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Gr1+IL-4-producing innate cells are induced in response to Th2 stimuli and suppress Th1-dependent antibody responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Pivotal advance: eosinophils mediate early alum adjuvant-elicited B cell priming and IgM production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

The inflammasome: a danger sensing complex triggering innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

CD8 T cell competition for dendritic cells in vivo is an early event in activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Using bicistronic IL-4 reporter mice to identify IL-4 expressing cells following immunisation with aluminium adjuvant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Naive and memory CD4+ T cell survival controlled by clonal abundance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Chemokines: immunology's high impact factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Mast cells mediate acute inflammatory responses to implanted biomaterials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Role of H1 receptors and P-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Complement activation by aluminium and zirconium compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Eosinophil Response to Alum Adjuvants: Involvement of T Cells in Non-Antigen-Dependent Mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Release of histamine from rat mast cells by the complement peptides C3a and C5a.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

28 July 2018

Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

Defining a link with asthma in mice congenitally deficient in eosinophils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

Potent induction of a neutrophil and eosinophil-rich infiltrate in vivo by human mast cell tryptase: selective enhancement of eosinophil recruitment by histamine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

Role of C3a and C5a in the activation of mast cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

29 October 2018

Interleukin-18 plays a role in both the alum-induced T helper 2 response and the T helper 1 response induced by alum-adsorbed interleukin-12

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

10 December 2018

Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2912728

10 December 2018

A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage 'suicide' technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production, characterisation and use of monoclonal antibodies to human interleukin-5 in an enzyme-linked immunosorbent assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nondegradative route for the removal of endotoxin from exopolysaccharides

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Airway hyperreactivity in exacerbation of chronic asthma is independent of eosinophilic inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of dendritic cells and induction of CD4(+) T cell differentiation by aluminum-containing adjuvants

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-1 enhances T cell-dependent antibody production through induction of CD40 ligand and OX40 on T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors control activation of adaptive immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19734227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0900164

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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