Human NK cells differ more in their KIR2DL1-dependent thresholds for HLA-Cw6-mediated inhibition than in their maximal killing capacity (Q34031624)

30 July 2017

title

Human NK cells differ more in their KIR2DL1-dependent thresholds for HLA-Cw6-mediated inhibition than in their maximal killing capacity (English)

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30 July 2017

Catarina R Almeida

1

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Daniel M. Davis

object named as

Daniel M Davis

5

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author name string

Amit Ashkenazi

2

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30 July 2017

Gitit Shahaf

3

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30 July 2017

Deborah Kaplan

4

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30 July 2017

Ramit Mehr

6

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30 July 2017

language of work or name

English

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publication date

19 September 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

9

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30 July 2017

page(s)

e24927

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

19 September 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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A human NK cell activation/inhibition threshold allows small changes in the target cell surface phenotype to dramatically alter susceptibility to NK cells.

5 July 2018

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Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice

5 July 2018

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Effects of MHC class I alleles on licensing of Ly49A+ NK cells.

5 July 2018

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Regulation of human NK-cell cytokine and chemokine production by target cell recognition.

5 July 2018

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Probing natural killer cell education by Ly49 receptor expression analysis and computational modelling in single MHC class I mice

5 July 2018

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NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model

5 July 2018

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HLA alleles determine differences in human natural killer cell responsiveness and potency

5 July 2018

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Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands

5 July 2018

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Intracellular cysteine residues in the tail of MHC class I proteins are crucial for extracellular recognition by leukocyte Ig-like receptor 1.

5 July 2018

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Membranous structures transfer cell surface proteins across NK cell immune synapses

5 July 2018

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Self-tolerance, dendritic cell (DC)-mediated activation and tissue distribution of natural killer (NK) cells

5 July 2018

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Segregation of HLA-C from ICAM-1 at NK cell immune synapses is controlled by its cell surface density

5 July 2018

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Human NK cell education by inhibitory receptors for MHC class I.

5 July 2018

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Impact of FASL-induced apoptosis in the elimination of tumor cells by NK cells

5 July 2018

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The mature activating natural killer cell immunologic synapse is formed in distinct stages

5 July 2018

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Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

5 July 2018

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Using carboxyfluorescein diacetate succinimidyl ester to monitor human NK cell division: analysis of the effect of activating and inhibitory class I MHC receptors

5 July 2018

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HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

5 July 2018

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HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

5 July 2018

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Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis

5 July 2018

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Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules

5 July 2018

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Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand

5 July 2018

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Production of human cells expressing individual transferred HLA-A,-B,-C genes using an HLA-A,-B,-C null human cell line

5 July 2018

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The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells

5 July 2018

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Simulations of the NK cell immune synapse reveal that activation thresholds can be established by inhibitory receptors acting locally

21 January 2018

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Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules

21 January 2018

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Ligand binding to inhibitory killer cell Ig-like receptors induce colocalization with Src homology domain 2-containing protein tyrosine phosphatase 1 and interruption of ongoing activation signals

21 January 2018

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CD107a as a functional marker for the identification of natural killer cell activity.

21 January 2018

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Serial killing of tumor cells by human natural killer cells--enhancement by therapeutic antibodies

21 January 2018

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NK cell education: not an on-off switch but a tunable rheostat.

21 January 2018

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Regulation of FasL expression in natural killer cells

21 January 2018

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IFN-gamma production and cytotoxicity of IL-2-activated murine NK cells are differentially regulated by MHC class I molecules

21 January 2018

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12 December 2020

Purified MHC class I molecules inhibit activated NK cells in a cell-free system in vitro

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12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

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12 December 2020

NK cell receptor calibration: effects of MHC class I induction on killing by Ly49Ahigh and Ly49Alow NK cells

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12 December 2020

Inhibitory Receptor Signals Suppress Ligation-Induced Recruitment of NKG2D to GM1-Rich Membrane Domains at the Human NK Cell Immune Synapse

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12 December 2020

Cytolytic activity of NK cell clones against acute childhood precursor-B-cell leukaemia is influenced by HLA class I expression on blasts and the differential KIR phenotype of NK clones

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0024927

Identifiers

DOI

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release_ihl6xmafpzgejgjajoknicuoqe

30 July 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ihl6xmafpzgejgjajoknicuoqe

24 November 2022

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PMC publication ID

3176315

1 reference

30 July 2017

1 reference