Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation (Q34032707)

30 July 2017

title

Rbx1 flexible linker facilitates cullin-RING ligase function before neddylation and after deneddylation (English)

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30 July 2017

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2

Ruth Nussinov

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30 July 2017

Jin Liu

1

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30 July 2017

language of work or name

English

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publication date

1 August 2010

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30 July 2017

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30 July 2017

volume

99

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30 July 2017

issue

3

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30 July 2017

page(s)

736-744

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Molecular dynamics reveal the essential role of linker motions in the function of cullin-RING E3 ligases

30 July 2017

cites work

1 reference

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The role of dynamic conformational ensembles in biomolecular recognition

5 July 2018

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The mechanism of ubiquitination in the cullin-RING E3 ligase machinery: conformational control of substrate orientation

5 July 2018

1 reference

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The origin of allosteric functional modulation: multiple pre-existing pathways

5 July 2018

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Recognition and processing of ubiquitin-protein conjugates by the proteasome

5 July 2018

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Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms

5 July 2018

1 reference

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Regulation of cullin-RING E3 ubiquitin-ligases by neddylation and dimerization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

5 July 2018

1 reference

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Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail

5 July 2018

1 reference

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Regulation of cullin RING ligases

5 July 2018

1 reference

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The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination

5 July 2018

1 reference

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Allostery: absence of a change in shape does not imply that allostery is not at play

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design

5 July 2018

1 reference

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Taking it step by step: mechanistic insights from structural studies of ubiquitin/ubiquitin-like protein modification pathways

5 July 2018

1 reference

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Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases

5 July 2018

1 reference

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Scalable molecular dynamics with NAMD

5 July 2018

1 reference

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The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae

5 July 2018

1 reference

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Is allostery an intrinsic property of all dynamic proteins?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

The SCF ubiquitin ligase: insights into a molecular machine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Folding and binding cascades: dynamic landscapes and population shifts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Folding and binding cascades: shifts in energy landscapes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Folding funnels, binding funnels, and protein function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

VMD: visual molecular dynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

Protein domain movements: detection of rigid domains and visualization of hinges in comparisons of atomic coordinates.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913186

10.1016/J.BPJ.2010.05.021

29 October 2018

Identifiers

DOI

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30 July 2017

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30 July 2017

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