What causes the build-up of ubiquitin-containing inclusions in Parkinson's disease? (Q34033999)

30 July 2017

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title

What causes the build-up of ubiquitin-containing inclusions in Parkinson's disease? (English)

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30 July 2017

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Andersen JK

1

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PubMed ID

10989121

30 July 2017

language of work or name

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1 September 2000

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Mechanisms of Ageing and Development

30 July 2017

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30 July 2017

118

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30 July 2017

1-2

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30 July 2017

15-22

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Ubiquitin, cellular inclusions and their role in neurodegeneration

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Use of genetically engineered mice as models for exploring the role of oxidative stress in neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

The ubiquitin-mediated proteolytic pathway: mechanisms of recognition of the proteolytic substrate and involvement in the degradation of native cellular proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

A Drosophila model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Resistance to cadmium mediated by ubiquitin-dependent proteolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Multicatalytic proteinase is present in Lewy bodies and neurofibrillary tangles in diffuse Lewy body disease brains.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

The ubiquitin pathway in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Endosome-lysosomes, ubiquitin and neurodegeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Alpha synuclein in neurodegenerative disorders: murderer or accomplice?

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Ubiquitin in homeostasis, development and disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Production of anti-polyubiquitin and anti-ubiquitin carboxyl terminal hydrolase antibodies and immunohistochemically assessment of them on brain sections of Alzheimer's disease and Lewy body disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Immunoelectron microscopic localization of ubiquitin in hepatoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Changes in heat shock protein 70 and ubiquitin mRNA levels in C1300 N2A mouse neuroblastoma cells following treatment with iron

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

Regulation of ubiquitin-dependent processes by deubiquitinating enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900150-0

7 January 2021

10.1016/S0047-6374(00)00150-0

Identifiers

DOI

1 reference

30 July 2017

1 reference

PubMed ID

10989121