Role of the gut microbiota in immunity and inflammatory disease (Q34036490)

30 July 2017

Role of the gut microbiota in immunity and inflammatory disease (English)

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30 July 2017

4

Gabriel Núñez

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30 July 2017

Nobuhiko Kamada

1

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30 July 2017

Sang-Uk Seo

series ordinal

2

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30 July 2017

Grace Y Chen

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3

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30 July 2017

language of work or name

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1 May 2013

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Nature Reviews Immunology

30 July 2017

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30 July 2017

13

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30 July 2017

321-335

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30 July 2017

5

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https://scigraph.springernature.com/pub.10.1038/nri3430

30 July 2017

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cites work

Immune adaptations that maintain homeostasis with the intestinal microbiota

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31 March 2020

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Mechanisms controlling pathogen colonization of the gut.

31 March 2020

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Role of the commensal microbiota in normal and pathogenic host immune responses

31 March 2020

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The microbiome in infectious disease and inflammation

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Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine

31 March 2020

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Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.

31 March 2020

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Adaptation of solitary intestinal lymphoid tissue in response to microbiota and chemokine receptor CCR7 signaling

31 March 2020

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Th17 and regulatory T cells in mediating and restraining inflammation

31 March 2020

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ATP drives lamina propria T(H)17 cell differentiation

31 March 2020

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Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine

31 March 2020

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Induction of intestinal Th17 cells by segmented filamentous bacteria

31 March 2020

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The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses

31 March 2020

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Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

31 March 2020

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Gut immune maturation depends on colonization with a host-specific microbiota

31 March 2020

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Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

31 March 2020

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Induction of colonic regulatory T cells by indigenous Clostridium species

31 March 2020

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Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

31 March 2020

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The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

31 March 2020

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Adaptive immune regulation in the gut: T cell-dependent and T cell-independent IgA synthesis

31 March 2020

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The role of secretory antibodies in infection immunity

31 March 2020

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Homeland security: IgA immunity at the frontiers of the body

31 March 2020

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Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

31 March 2020

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Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense

31 March 2020

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IgA response to symbiotic bacteria as a mediator of gut homeostasis

31 March 2020

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The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.

31 March 2020

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Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells

31 March 2020

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Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5.

31 March 2020

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Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells.

31 March 2020

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Prominent role for plasmacytoid dendritic cells in mucosal T cell-independent IgA induction

31 March 2020

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Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut

31 March 2020

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Innate lymphoid cells--how did we miss them?

31 March 2020

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Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease

31 March 2020

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A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

31 March 2020

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The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

31 March 2020

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Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

31 March 2020

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RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

31 March 2020

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RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

31 March 2020

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Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

31 March 2020

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The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine

31 March 2020

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Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

31 March 2020

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Bifidobacteria can protect from enteropathogenic infection through production of acetate

31 March 2020

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Effect of streptomycin on susceptibility of intestinal tract to experimental Salmonella infection

31 March 2020

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In vivo and in vitro antagonism of intestinal bacteria against Shigella flexneri. I. Correlation between various tests

31 March 2020

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Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts

31 March 2020

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Clostridium difficile infection: new developments in epidemiology and pathogenesis

31 March 2020

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Competition for proline between indigenous Escherichia coli and E. coli O157:H7 in gnotobiotic mice associated with infant intestinal microbiota and its contribution to the colonization resistance against E. coli O157:H7.

31 March 2020

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Effect of organic acids on inhibition of Escherichia coli O157:H7 colonization in gnotobiotic mice associated with infant intestinal microbiota.

31 March 2020

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Comparison of carbon nutrition for pathogenic and commensal Escherichia coli strains in the mouse intestine

31 March 2020

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Precolonized human commensal Escherichia coli strains serve as a barrier to E. coli O157:H7 growth in the streptomycin-treated mouse intestine

31 March 2020

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Regulated virulence controls the ability of a pathogen to compete with the gut microbiota.

31 March 2020

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The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal Salmonella diarrhea

31 March 2020

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Fucose sensing regulates bacterial intestinal colonization

31 March 2020

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Sugar metabolism, an additional virulence factor in enterobacteria

31 March 2020

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Enterohaemorrhagic Escherichia coli gains a competitive advantage by using ethanolamine as a nitrogen source in the bovine intestinal content

31 March 2020

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Gut inflammation provides a respiratory electron acceptor for Salmonella

31 March 2020

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Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota

31 March 2020

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The opportunistic pathogen Serratia marcescens utilizes type VI secretion to target bacterial competitors.

31 March 2020

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Promoter swapping unveils the role of the Citrobacter rodentium CTS1 type VI secretion system in interbacterial competition

31 March 2020

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The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

31 March 2020

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Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa

31 March 2020

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Importance and regulation of the colonic mucus barrier in a mouse model of colitis

31 March 2020

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Symbiotic bacteria direct expression of an intestinal bactericidal lectin

31 March 2020

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MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection

31 March 2020

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Toll-like receptor 2 is critical for induction of Reg3 beta expression and intestinal clearance of Yersinia pseudotuberculosis

31 March 2020

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Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice

31 March 2020

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Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

31 March 2020

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NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

31 March 2020

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Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria

31 March 2020

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Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles

31 March 2020

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The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells

31 March 2020

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Microbial exposure during early life has persistent effects on natural killer T cell function

31 March 2020

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A microbial symbiosis factor prevents intestinal inflammatory disease

31 March 2020

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Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-kappaB activation

31 March 2020

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A primitive T cell-independent mechanism of intestinal mucosal IgA responses to commensal bacteria

31 March 2020

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Peripheral education of the immune system by colonic commensal microbiota.

31 March 2020

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Acute gastrointestinal infection induces long-lived microbiota-specific T cell responses

31 March 2020

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Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism

31 March 2020

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Transient TLR activation restores inflammatory response and ability to control pulmonary bacterial infection in germfree mice

31 March 2020

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Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

31 March 2020

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Microbiota regulates immune defense against respiratory tract influenza A virus infection

31 March 2020

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Commensal bacteria calibrate the activation threshold of innate antiviral immunity

31 March 2020

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Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota.

31 March 2020

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Gut commensal bacteria direct a protective immune response against Toxoplasma gondii.

31 March 2020

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Compartmentalized control of skin immunity by resident commensals

31 March 2020

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Metabolism of bile salts in mice influences spore germination in Clostridium difficile

31 March 2020

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Successful transmission of a retrovirus depends on the commensal microbiota

31 March 2020

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Intestinal microbiota promote enteric virus replication and systemic pathogenesis

31 March 2020

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The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

31 March 2020

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Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis

31 March 2020

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Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

31 March 2020

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Role of toll-like receptors in spontaneous commensal-dependent colitis

31 March 2020

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MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

31 March 2020

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Epithelial NEMO links innate immunity to chronic intestinal inflammation

31 March 2020

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Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

31 March 2020

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The genetics and immunopathogenesis of inflammatory bowel disease

31 March 2020

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

31 March 2020

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

31 March 2020

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

31 March 2020

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A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

31 March 2020

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Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

31 March 2020

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Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

31 March 2020

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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

31 March 2020

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ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis

31 March 2020

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Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

31 March 2020

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Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

31 March 2020

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NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

31 March 2020

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Nod2 is required for the regulation of commensal microbiota in the intestine

31 March 2020

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

31 March 2020

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Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

31 March 2020

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Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria.

31 March 2020

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Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic interleukin-2-deficient mice.

31 March 2020

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Host gene expression in the colon of gnotobiotic interleukin-2-deficient mice colonized with commensal colitogenic or noncolitogenic bacterial strains: common patterns and bacteria strain specific signatures

31 March 2020

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Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease

31 March 2020

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Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

31 March 2020

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Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitis

31 March 2020

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The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

31 March 2020

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NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

31 March 2020

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Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice

31 March 2020

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Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer

31 March 2020

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The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis

31 March 2020

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A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

31 March 2020

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Intestinal inflammation targets cancer-inducing activity of the microbiota.

31 March 2020

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Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

31 March 2020

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The keystone-pathogen hypothesis.

31 March 2020

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Dextran sodium sulfate-induced colitis in germ-free IQI/Jic mice

31 March 2020

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Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

31 March 2020

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Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma

31 March 2020

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Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

31 March 2020

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Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

31 March 2020

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B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage.

31 March 2020

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Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis.

31 March 2020

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Toll-like receptor 9-induced type I IFN protects mice from experimental colitis

31 March 2020

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Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

31 March 2020

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An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system

31 March 2020

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Outer membrane vesicles of a human commensal mediate immune regulation and disease protection

31 March 2020

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Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells

31 March 2020

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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

31 March 2020

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Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis

31 March 2020

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Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

31 March 2020

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Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.

31 March 2020

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A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

31 March 2020

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Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

31 March 2020

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IL-17 production from activated T cells is required for the spontaneous development of destructive arthritis in mice deficient in IL-1 receptor antagonist

31 March 2020

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Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

31 March 2020

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

31 March 2020

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Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice.

31 March 2020

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Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice.

31 March 2020

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Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity.

31 March 2020

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Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation

31 March 2020

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Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy.

31 March 2020

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31 March 2020

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Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis

31 March 2020

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Cystic fibrosis transmembrane conductance regulator knockout mice exhibit aberrant gastrointestinal microbiota

31 March 2020

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Fecal microbiota transplantation and emerging applications

31 March 2020

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Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

31 March 2020

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Essential contribution of IRF3 to intestinal homeostasis and microbiota-mediated Tslp gene induction

31 March 2020

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Deletion of TLR5 results in spontaneous colitis in mice

31 March 2020

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12 December 2020

Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis

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12 December 2020

Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli

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12 December 2020

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.

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12 December 2020

Effect of the gastrointestinal microflora on induction and maintenance of oral tolerance to ovalbumin in C3H/HeJ mice

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12 December 2020

IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation

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12 December 2020

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

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12 December 2020

INFECTION OF GERMEREE MICE WITH SHIGELLA FLEXNERI 3A

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12 December 2020

T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment

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12 December 2020

Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice

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12 December 2020

Identifiers

DOI

10.1038/NRI3430

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Dimensions Publication ID

30 July 2017

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