FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver (Q34037648)

30 July 2017

title

FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver (English)

1 reference

30 July 2017

0 references

Michelle E Marcus

1

1 reference

30 July 2017

Joshua N Leonard

series ordinal

2

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30 July 2017

publication date

1 January 2013

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

5

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30 July 2017

page(s)

659-680

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

29 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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miR-1289 and "Zipcode"-like Sequence Enrich mRNAs in Microvesicles

5 July 2018

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Activated human T cells secrete exosomes that participate in IL-2 mediated immune response signaling

5 July 2018

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Exosome-mediated delivery of siRNA in vitro and in vivo

5 July 2018

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Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension.

5 July 2018

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Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells

5 July 2018

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Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft model

5 July 2018

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Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth

5 July 2018

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Immune surveillance properties of human NK cell-derived exosomes.

5 July 2018

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Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery

5 July 2018

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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

5 July 2018

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Exosome mimetics: a novel class of drug delivery systems

5 July 2018

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Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes.

5 July 2018

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Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth

5 July 2018

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Activated T cell exosomes promote tumor invasion via Fas signaling pathway

5 July 2018

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Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Tumor cell-derived exosomes: a message in a bottle

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials.

5 July 2018

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Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Altering the immune response with lipid-based nanoparticles.

5 July 2018

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Competitive interactions of cancer cells and normal cells via secretory microRNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

EBV-gp350 confers B-cell tropism to tailored exosomes and is a neo-antigen in normal and malignant B cells--a new option for the treatment of B-CLL

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Increasing vaccine potency through exosome antigen targeting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Targeted drug delivery using immunoconjugates: principles and applications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

ExoCarta 2012: database of exosomal proteins, RNA and lipids

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: prediction and prevention

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Interaction and uptake of exosomes by ovarian cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Protein targeting to exosomes/microvesicles by plasma membrane anchors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Microvesicle-mediated RNA molecule delivery system using monocytes/macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Human tumor virus utilizes exosomes for intercellular communication.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Secretory microRNAs as a versatile communication tool

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Secretory mechanisms and intercellular transfer of microRNAs in living cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Functional delivery of viral miRNAs via exosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Subcellular targeting strategies for drug design and delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Microenvironmental pH is a key factor for exosome traffic in tumor cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Silencing by small RNAs is linked to endosomal trafficking

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Membrane vesicles as conveyors of immune responses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Biological gene delivery vehicles: beyond viral vectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Prospects for exosomes in immunotherapy of cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

RETRACTED: Pregnancy-associated exosomes and their modulation of T cell signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Immature dendritic cell-derived exosomes can mediate HIV-1 trans infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

The Trojan exosome hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Differential secretion of Fas ligand- or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Mast cell-dependent B and T lymphocyte activation is mediated by the secretion of immunologically active exosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

B lymphocytes secrete antigen-presenting vesicles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Uptake of liposomes by cultured mouse bone marrow macrophages: influence of liposome composition and size

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3722064

Exfoliation of membrane ecto-enzymes in the form of micro-vesicles

5 July 2018

1 reference

Antigen-loaded exosomes alone induce Th1-type memory through a B-cell-dependent mechanism.

21 January 2018

1 reference

Fragments of antigen-loaded dendritic cells (DC) and DC-derived exosomes induce protective immunity against Leishmania major.

21 January 2018

1 reference

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury.

21 January 2018

1 reference

Dendritic Cells Recruit T Cell Exosomes via Exosomal LFA-1 Leading to Inhibition of CD8+ CTL Responses through Downregulation of Peptide/MHC Class I and Fas Ligand-Mediated Cytotoxicity

21 January 2018

1 reference

Exosome isolation for proteomic analyses and RNA profiling.

21 January 2018

1 reference

Production and characterization of clinical grade exosomes derived from dendritic cells.

21 January 2018

1 reference

Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

21 January 2018

1 reference

Enhancement of immunostimulatory properties of exosomal vaccines by incorporation of fusion-competent G protein of vesicular stomatitis virus

21 January 2018

1 reference

Galectin-5 is bound onto the surface of rat reticulocyte exosomes and modulates vesicle uptake by macrophages

21 January 2018

1 reference

Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59.

21 January 2018

1 reference

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

21 January 2018

1 reference

Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells

21 January 2018

1 reference

12 December 2020

Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo

1 reference

12 December 2020

Exosomes from bone marrow dendritic cells pulsed with diphtheria toxoid preferentially induce type 1 antigen-specific IgG responses in naive recipients in the absence of free antigen

1 reference

12 December 2020

Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express IL-4

1 reference

12 December 2020

Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive

1 reference

12 December 2020

Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer

1 reference

12 December 2020

Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis

1 reference

12 December 2020

Identifiers

DOI

10.3390/PH6050659

1 reference

30 July 2017

1 reference

30 July 2017

1 reference