Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders. (Q34039895)

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English	Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.	scientific article

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16 January 2020

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders (English)

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Michael William Vogel

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Y Ayhan

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B Abazyan

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R Kim

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B Ladenheim

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I N Krasnova

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A Sawa

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R L Margolis

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J L Cadet

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S Mori

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C A Ross

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M V Pletnikov

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Molecular Psychiatry

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293-306

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16 January 2020

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Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

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Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

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Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

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Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia

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New genes associated with schizophrenia in neurite formation: a review of cell culture experiments

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PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation

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5 July 2018

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5 July 2018

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5 July 2018

A review of MRI findings in schizophrenia

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5 July 2018

Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia.

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5 July 2018

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5 July 2018

Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia.

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5 July 2018

Structural abnormalities of subicular dendrites in subjects with schizophrenia and mood disorders: preliminary findings

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5 July 2018

Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method

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5 July 2018

A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.

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21 January 2018

Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1).

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21 January 2018

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

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21 January 2018

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

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21 January 2018

Enhanced BDNF signaling is associated with an antidepressant-like behavioral response and changes in brain monoamines

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21 January 2018

Effects of genetic background on neonatal Borna disease virus infection-induced neurodevelopmental damage. I. Brain pathology and behavioral deficits

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Behavioral phenotypes of Disc1 missense mutations in mice.

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Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

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21 January 2018

Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling.

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21 January 2018

Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice

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21 January 2018

Phospholipase C-beta1 knockout mice exhibit endophenotypes modeling schizophrenia which are rescued by environmental enrichment and clozapine administration.

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21 January 2018

Locomotor reactivity to a novel environment and sensitivity to MK-801 in five strains of mice

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21 January 2018

Progressive cortical change during adolescence in childhood-onset schizophrenia. A longitudinal magnetic resonance imaging study.

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21 January 2018

Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia

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21 January 2018

Dendritic spine density in schizophrenia and depression

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21 January 2018

Differential expression of disrupted-in-schizophrenia (DISC1) in bipolar disorder.

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21 January 2018

Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.

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21 January 2018

The development of parvalbumin-immunoreactivity in the neocortex of the mouse.

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21 January 2018

Heritability of changes in brain volume over time in twin pairs discordant for schizophrenia.

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Longitudinal MRI study in schizophrenia patients and their healthy siblings.

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21 January 2018

Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development.

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21 January 2018

Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment.

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21 January 2018

Association of DISC1 and TSNAX genes and affective disorders in the depression case-control (DeCC) and bipolar affective case-control (BACCS) studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914807

28 October 2018

A selective reduction in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2914807

28 October 2018

Schizophrenia genes - famine to feast

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiology of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular administration of substance P increases dopamine content in the brain of 6-hydroxydopamine-lesioned rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/20048751

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MP.2009.144

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20048751%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20048751%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20048751%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

ResearchGate publication ID

0 references

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