In vivo genome editing using Staphylococcus aureus Cas9 (Q34043628)

30 July 2017

In vivo genome editing using Staphylococcus aureus Cas9 (English)

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30 July 2017

Staphylococcus aureus

1 reference

0 references

Jonathan S. Gootenberg

object named as

Jonathan S Gootenberg

5

0 references

Xuebing Wu

object named as

Xuebing Wu

9

0 references

Eugene Koonin

11

object named as

Eugene V Koonin

1 reference

30 July 2017

10

Kira S Makarova

1 reference

30 July 2017

3

Winston X Yan

1 reference

30 July 2017

7

Bernd Zetsche

1 reference

30 July 2017

F Ann Ran

1

1 reference

30 July 2017

Le Cong

2

1 reference

30 July 2017

David A Scott

4

1 reference

30 July 2017

Andrea J Kriz

6

1 reference

30 July 2017

Ophir Shalem

8

1 reference

30 July 2017

Phillip A Sharp

12

1 reference

30 July 2017

Feng Zhang

13

1 reference

30 July 2017

language of work or name

English

0 references

publication date

1 April 2015

1 reference

30 July 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

Nature

1 reference

30 July 2017

520

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30 July 2017

7546

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30 July 2017

186-191

1 reference

https://scigraph.springernature.com/pub.10.1038/nature14299

30 July 2017

0 references

cites work

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5 July 2018

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In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

5 July 2018

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CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox

5 July 2018

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Development and applications of CRISPR-Cas9 for genome engineering

5 July 2018

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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences

5 July 2018

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Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

5 July 2018

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Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

5 July 2018

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Classification and evolution of type II CRISPR-Cas systems

5 July 2018

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Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

5 July 2018

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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

5 July 2018

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Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

5 July 2018

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Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial

5 July 2018

1 reference

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Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

5 July 2018

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High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

5 July 2018

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

5 July 2018

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DNA targeting specificity of RNA-guided Cas9 nucleases

5 July 2018

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

5 July 2018

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The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems

5 July 2018

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Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

5 July 2018

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RNA-guided human genome engineering via Cas9

5 July 2018

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Multiplex genome engineering using CRISPR/Cas systems

5 July 2018

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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

5 July 2018

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Identifying ChIP-seq enrichment using MACS.

5 July 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

5 July 2018

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The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

5 July 2018

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Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

5 July 2018

1 reference

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Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges

5 July 2018

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State-of-the-art gene-based therapies: the road ahead

5 July 2018

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CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

5 July 2018

1 reference

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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

5 July 2018

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Review of the clinical development of alipogene tiparvovec gene therapy for lipoprotein lipase deficiency

5 July 2018

1 reference

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Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

5 July 2018

1 reference

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Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

5 July 2018

1 reference

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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

5 July 2018

1 reference

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Molecular biology of PCSK9: its role in LDL metabolism

5 July 2018

1 reference

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Precise hit: adeno-associated virus in gene targeting

5 July 2018

1 reference

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Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

New recombinant serotypes of AAV vectors.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

WebLogo: A Sequence Logo Generator

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

Mfold web server for nucleic acid folding and hybridization prediction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

RNAMotif, an RNA secondary structure definition and search algorithm

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

Direct RNA motif definition and identification from multiple sequence alignments using secondary structure profiles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

Recent progress in understanding apolipoprotein B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4393360

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14299

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14299

Guide RNA functional modules direct Cas9 activity and orthogonality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14299

Model-based analysis of ChIP-Seq (MACS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14299

21 January 2018

Identifiers

DOI

10.1038/NATURE14299

1 reference

Dimensions Publication ID

30 July 2017

1019168198

0 references

Fatcat ID

release_rppjjhmzn5c4hc7x7ch5onggga

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rppjjhmzn5c4hc7x7ch5onggga

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

4393360

1 reference

30 July 2017

1 reference