Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa (Q34044604)

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English	Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa	scientific article

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12 October 2019

Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa (English)

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12 October 2019

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Rajewsky K

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Zou YR

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12 October 2019

Takeda S

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1 March 1993

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12 October 2019

The EMBO Journal

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12 October 2019

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12 October 2019

811-820

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12 October 2019

B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Organization of four mouse lambda light chain immunoglobulin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Human immunoglobulin kappa light-chain genes are deleted or rearranged in lambda-producing B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

High frequency of lambda gene activation in bone marrow pre-B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Somatic generation of antibody diversity

1 reference

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5 July 2018

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

A uniform deleting element mediates the loss of kappa genes in human B cells.

1 reference

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5 July 2018

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Ig lambda-producing B cells do not show feedback inhibition of gene rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Structure of a third murine immunoglobulin lambda light chain variable region that is expressed in laboratory mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Detection of normal B-cell precursors that give rise to colonies producing both kappa and lambda light immunoglobulin chains

1 reference

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5 July 2018

A new variable region in mouse immunoglobulin lambda light chains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

The human kappa deleting element and the mouse recombining segment share DNA sequence homology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

The human CK gene segment and the kappa deleting element are closely linked

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Frequent lambda light chain gene rearrangement and expression in a Ly-1 B lymphoma with a productive kappa chain allele

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Regulation of genome rearrangement events during lymphocyte differentiation

1 reference

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5 July 2018

Active lambda and kappa antibody gene rearrangement in Abelson murine leukemia virus-transformed pre-B cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Identification of a monoclonal antibody specific for a murine T3 polypeptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Ordered activation of the Ig lambda locus in Abelson B cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Light-chain gene expression before heavy-chain gene rearrangement in pre-B cells transformed by Epstein-Barr virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

A critique of the Cohn-Langman protection theory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

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The protecton: the unit of humoral immunity selected by evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Immunoglobulin lambda gene rearrangement can precede kappa gene rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Murine lambda gene rearrangements: the stochastic model prevails over the ordered model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Lack of feedback inhibition of V kappa gene rearrangement by productively rearranged alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Establishment of a germ-line competent C57BL/6 embryonic stem cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Independent rearrangement of Ig lambda genes in tissue culture-derived murine B cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Most peripheral B cells in mice are ligand selected

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Recombinase-mediated gene activation and site-specific integration in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Ongoing V kappa-J kappa recombination after formation of a productive V kappa-J kappa coding joint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

The murine kappa light chain shift

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

5 July 2018

Estimate of the light chain repertoire size of fetal and adult BALB/cJ and CBA/J mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

28 October 2018

Novel kappa light-chain gene rearrangements in mouse lambda light chain-producing B lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

28 October 2018

Sets of immunoglobulin V kappa genes homologous to ten cloned V kappa sequences: implications for the number of germline V kappa genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

28 October 2018

The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

28 October 2018

A new V gene expressed in lambda-2 light chains of the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413278

28 October 2018

Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lambda chain expression at different stages of ontogeny in C57BL/6, BALB/c and SJL mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

kappa/lambda Shifts do not occur during maturation of murine B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface membrane kappa and lambda light chain expression on spleen cells of neonatal and maturing normal and immune-defective CBA/NB mice: the kappa:lambda ratio is constant

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface antigen expression and immunoglobulin gene rearrangement during mouse pre-B cell development

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The level of λ1 light chain expression in the mouse reflects the probability of rearrangement of the relevant gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kappa/lambda ratio in surface immunoglobulin molecules on B lymphocytes differentiating from DHJH-rearranged murine pre-B cell clones in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of immunoglobulin heavy chain expression results in altered kappa/lambda light chain ratios

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The frequency of multiple recombination events occurring at the human Ig kappa L chain locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/8458339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1993.TB05721.X

1 reference

Europe PubMed Central

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12 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8458339%20AND%20SRC:MED&resulttype=core&format=json

12 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8458339%20AND%20SRC:MED&resulttype=core&format=json

12 October 2019

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