Live or let die - retinal ganglion cell death and survival during development and in the lesioned adult CNS. (Q34046206)

30 July 2017

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title

Live or let die - retinal ganglion cell death and survival during development and in the lesioned adult CNS. (English)

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30 July 2017

retinal ganglion cell

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Bähr M

1

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30 July 2017

1 October 2000

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30 July 2017

Trends in Neurosciences

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30 July 2017

23

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30 July 2017

10

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30 July 2017

483-490

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A sensitive period for ganglion cell degeneration and the formation of aberrant retino-fugal connections following tectal lesions in rats.

30 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

The visual response of retinal ganglion cells is not altered by optic nerve transection in transgenic mice overexpressing Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

1 reference

7 January 2021

Neuronal cell death: a demise with different shapes.

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7 January 2021

Pathobiology of ischaemic stroke: an integrated view

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7 January 2021

Neuronal apoptosis in acute necrotic insults: why is this subject such a mess?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Defects in regulation of apoptosis in caspase-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Retinal ganglion cell loss after the period of naturally occurring cell death in bcl-2-/- mice

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https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice

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https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Bcl-xL is an antiapoptotic regulator for postnatal CNS neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Physiological and induced neuronal death are not affected in NSE-bax transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Neurotrophins in cell survival/death decisions.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Caspases: killer proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Regulated targeting of BAX to mitochondria.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Cytochrome c: can't live with it--can't live without it.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

A comparison of the cytoplasmic domains of the Fas receptor and the p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Neurotrophic survival molecules for motoneurons: an embarrassment of riches

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Neurotrophin-3 antibodies disrupt the normal development of the chick retina

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Survival and Axonal Elongation of Adult Rat Retinal Ganglion Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Short communication: protection of axotomized retinal ganglion cells by adenovirally delivered BDNF in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Both the neuronal and inducible isoforms contribute to upregulation of retinal nitric oxide synthase activity by brain-derived neurotrophic factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells In vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Structural and functional properties of the TRK family of neurotrophin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Insulin-Like Growth Factor-I Protects Axotomized Rat Retinal Ganglion Cells from Secondary Death via PI3-K-Dependent Akt Phosphorylation and Inhibition of Caspase-3

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Role of MAP kinase in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Raf revealed in life-or-death decisions

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Retinal ganglion cells lose trophic responsiveness after axotomy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Expression of p75 neurotrophin receptor in the injured and regenerating rat retina

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Axonal transport blockade in the neonatal rat optic nerve induces limited retinal ganglion cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculus.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

Transduction of axotomized retinal ganglion cells by adenoviral vector administration at the optic nerve stump: an in vivo model system for the inhibition of neuronal apoptotic cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2800%2901637-4

7 January 2021

10.1016/S0166-2236(00)01637-4

Identifiers

DOI

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30 July 2017

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PubMed ID

11006465